Genomic Applications in Prevention and Practice (GAPPNET) A Scientific Foundation for Implementing Genomics and Precision Medicine Applications in Cancer Control and Prevention

基因组学在预防和实践中的应用 (GAPPNET) 在癌症控制和预防中实施基因组学和精准医学应用的科学基础

• 批准号: 10281510
• 负责人: Michael Bowen
• 金额: $ 17.5万
• 依托单位: NATIONAL CANCER INSTITUTE
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10281510
• 关键词: Advanced Malignant Neoplasm; Affect; Agreement; Benchmarking; Cancer Burden; Cancer Control; Centers for Disease Control and Prevention (U.S.); Clinical; Collaborations; Communication; Consultations; Division of Cancer Control and Population Sciences; Division of Cancer Prevention; Ensure; Evaluation; Family member; Foundations; Funding; General Population; Genomic medicine; Genomics; Germ-Line Mutation; Health; Health Personnel; Health system; Healthcare; Hereditary Malignant Neoplasm; Hereditary Nonpolyposis Colorectal Neoplasms; Intervention; Learning; Malignant Neoplasms; Needs Assessment; Oncology; Output; Persons; Pharmacology; Population; Prevention; Prevention strategy; Public Health; Recommendation; Research; Resources; Science; Testing; Training; Translating; cancer genetics; cancer genomics; cancer prevention; evidence base; implementation strategy; mortality; population health; practical application; precision medicine; precision oncology; programs; tool

The purpose of this agreement is to effectively translate and responsibly advance cancer genomics and precision medicine into clinical and public health programs that can reduce the burden of cancer occurrence and mortality in the US. Under the terms of this agreement, OGPPH will provide technical assistance and collaborations to DCCPS to 1) identify and disseminate information about emerging cancer genomic and precision medicine applications; 2) strengthen healthcare-public health collaborations and partnerships in translating evidence into clinical and public health action; 3) develop and disseminate tools and resources to help integrate cancer genomics into programs, 4) conduct evidence-based evaluations and health impact analyses for best practices and ways of implementation; 5) develop population metrics and indicators for successful integration of cancer precision medicine and genomics into population health programs; 6) provide training and consultation to public health departments and health care providers; 7) develop communication products for public health and healthcare providers and for the general public. Under this agreement, DCCPS will transfer 175K to OGPPH in FY2020. The terms of the agreement will be revisited every year and evaluated on the basis of benefits to DCCPS.

该协议的目的是有效地将癌症基因组学和精准医学转化为临床和公共卫生计划，以减少美国癌症发生和死亡的负担。根据协议条款，OGPPH将为DCCPS提供技术援助和合作，以1）识别和传播有关新兴癌症基因组和精准医学应用的信息; 2）加强医疗保健-公共卫生合作和伙伴关系，将证据转化为临床和公共卫生行动; 3）开发和传播工具和资源，以帮助将癌症基因组学纳入计划，4）进行基于证据的评估和健康影响分析，以获得最佳实践和实施方式; 5）制定人口指标和指标，将癌症精准医学和基因组学成功整合到人口健康计划中; 6）为公共卫生部门和医疗保健提供者提供培训和咨询; 7）为公共卫生和医疗保健提供者以及公众开发通信产品。 根据该协议，DCCPS将在2020财年向OGPPH转移175 K。协议的条款将每年重新审查，并根据对DCCPS的好处进行评估。