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Advancing the technology readiness level of rapid additive manufacturing microfluidic technology for personalised medicine and organ-on-a-chip applications.

Advancing the technology readiness level of rapid additive manufacturing microfluidic technology for personalised medicine and organ-on-a-chip applications.
提高用于个性化医疗和芯片器官应用的快速增材制造微流体技术的技术准备水平。
批准号:
10044406
负责人:
金额:
$6.31万
依托单位国家:
英国
项目类别:
Grant for R&D
财政年份:
2022
资助国家:
英国
项目状态:
已结题
起止时间:
2022 至 --

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中文摘要
翻译
前沿空间技术使生物医学和制药研究能够在太空中进行,以造福于地球上的生命科学应用。在这种情况下,我们的主要产品是空间实验室,这是一个能够在太空进行各种生物医学研究活动的微型实验室。每个空间实验室都是完全自主的、远程控制的,大约有鞋盒大小。它搭载了一系列科学硬件,包括32个多腔样品盘、显微镜、微流体系统以及温度、压力和大气成分传感器。由于太空中存在的自然栖息地,主要是微重力和高辐射,进行这种研究有很多好处。这意味着,在太空中进行个性化医学、单芯片器官、药物开发、器官和组织3D打印、干细胞研究和蛋白质结晶等领域的科学研究将大大便利。同样的技术可以被带到地球上,作为一种自我驱动的医疗保健和分散的医疗保健的诊断工具。这项研究的结果最初将使地球和地球上的应用程序受益。在Innovate UK项目中,Frontier公司决心进行为期6个月的研究,旨在利用生物兼容的3D打印机推进个性化医学和芯片器官所需硬件的TRL。除此之外,该项目还将允许Frontier进入与这些领域和资金相关的新市场。
英文摘要
Frontier Space Technologies enable biomedical and pharmaceutical research in space for the benefit of life science applications on Earth.In this context, our main product is Space Lab, a miniaturized lab is capable of performing a wide variety of biomedical research activities in space. Each Space Lab is fully autonomous, remotely controlled, and approximately the size of a shoe box. It has a range of scientific hardware onboard including a 32 multi-chambered sample disc, a microscope, a microfluidics system and temperature, pressure and atmospheric composition sensors.Performing this kind of research has numerous benefits thanks to the natural habitat present in space, mainly microgravity and high radiation. This means that scientific research in the fields of personalized medicine, organ-on-a-chip, drug development, organ and tissue 3D printing, stem cell study, and protein crystallization is greatly facilitated when performed in space. The same technology can be brought down to Earth as a diagnostic tool for self-driven health care and de-centralised health careThe outcome of this research will initially benefit Earth and terrestrial applications.Within the Innovate UK project, Frontier is determined to perform a 6 months research period aimed at advancing the TRL of the hardware needed for personalised medicine and organ-on-a-chip, using a biocompatible 3D printer. In addition to this, this project will also allow Frontier to access new markets related to these field and funding.
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