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Advancing the technology readiness level of rapid additive manufacturing microfluidic technology for personalised medicine and organ-on-a-chip applications.

Advancing the technology readiness level of rapid additive manufacturing microfluidic technology for personalised medicine and organ-on-a-chip applications.
提高用于个性化医疗和芯片器官应用的快速增材制造微流体技术的技术准备水平。
批准号:
10044406
负责人:
金额:
$6.31万
依托单位国家:
英国
项目类别:
Grant for R&D
财政年份:
2022
资助国家:
英国
项目状态:
已结题
起止时间:
2022 至 --

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中文摘要
翻译
Frontier Space Technologies致力于在太空开展生物医学和制药研究,以造福地球上的生命科学应用。在这方面,我们的主要产品是Space Lab,这是一个小型化的实验室,能够在太空中进行各种生物医学研究活动。每个太空实验室都是完全自主的,远程控制的,大约有一个鞋盒大小。它搭载了一系列科学硬件,包括32个多室样品盘、显微镜、微流体系统以及温度、压力和大气成分传感器。由于太空中存在的自然栖息地,主要是微重力和高辐射,进行这种研究有许多好处。这意味着在太空中进行个性化医疗、器官芯片、药物开发、器官和组织3D打印、干细胞研究和蛋白质结晶等领域的科学研究将得到极大的促进。同样的技术也可以作为一种诊断工具应用于自我驱动的医疗保健和去中心化的医疗保健这项研究的结果将首先有利于地球和陆地应用。在英国创新项目中,Frontier决定进行为期6个月的研究,旨在使用生物相容性3D打印机推进个性化医疗和器官芯片所需硬件的TRL。除此之外,该项目还将使Frontier进入与这些领域和资金相关的新市场。
英文摘要
Frontier Space Technologies enable biomedical and pharmaceutical research in space for the benefit of life science applications on Earth.In this context, our main product is Space Lab, a miniaturized lab is capable of performing a wide variety of biomedical research activities in space. Each Space Lab is fully autonomous, remotely controlled, and approximately the size of a shoe box. It has a range of scientific hardware onboard including a 32 multi-chambered sample disc, a microscope, a microfluidics system and temperature, pressure and atmospheric composition sensors.Performing this kind of research has numerous benefits thanks to the natural habitat present in space, mainly microgravity and high radiation. This means that scientific research in the fields of personalized medicine, organ-on-a-chip, drug development, organ and tissue 3D printing, stem cell study, and protein crystallization is greatly facilitated when performed in space. The same technology can be brought down to Earth as a diagnostic tool for self-driven health care and de-centralised health careThe outcome of this research will initially benefit Earth and terrestrial applications.Within the Innovate UK project, Frontier is determined to perform a 6 months research period aimed at advancing the TRL of the hardware needed for personalised medicine and organ-on-a-chip, using a biocompatible 3D printer. In addition to this, this project will also allow Frontier to access new markets related to these field and funding.
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