Tai Chi intervention to improve chronic pain management for adults with HIV

项目摘要/摘要 候选人。我很高兴能向NCCIH提交K23奖项的申请。到目前为止，我收到了高质量的 作为临床健康心理学的科学家和实践者进行培训，强调对艾滋病毒人群的研究。至 成为一名独立的调查员，拥有一个研究项目，重点是使用身心干预来 管理慢性病，我需要在干预设计、实施和评估方面的额外培训。 培训计划。我参加K23大奖的训练目标包括：1)扩展我的身心知识 慢性疼痛管理的干预措施；2)发展成人艾滋病毒携带者治疗方面的专门知识 和慢性疼痛；3)培养临床试验方法的高级技能；4)开发、实施和评估 太极治疗艾滋病毒携带者慢性疼痛的试点试验；以及5)继续我的 作为一名独立资助的调查员，向成功的职业生涯发展。 环境在获奖期间，我将担任精神病学系的助理教授和 布朗大学的人类行为(DPHB)和行为和研究中心的研究科学家 Miriam医院的预防医学(CBPM)。DPHB是中国最顶尖的学术机构之一 美国的精神病学，有大约200项正在进行的研究和5000万美元的外部资金 赞助的研究。公共房屋局在为市民提供合适环境方面，成绩斐然。 圆满完成K个奖项。CBPM提供了一个出色的研究环境，支持教师 在发展最先进的科学研究方面，通过培养激励的智力环境来进行规划研究 这鼓励了合作。米里亚姆医院是免疫中心的所在地，这是一家城市艾滋病毒诊所 为1700名感染艾滋病毒的患者提供全面的初级和专科护理，是主要组成部分 这是布朗大学和波士顿大学的联合研究成果。 导师。我已经建立了一个专家指导团队，由心身领域的顶尖科学家组成。 研究、行为干预、艾滋病毒药物、慢性疼痛管理和定性方法。 建议的研究。与NCCIH、艾滋病研究办公室和 NIH的联邦疼痛研究战略(FPR)，拟议的研究解决了非药理学方面的空白 被忽视的慢性疼痛群体[即艾滋病毒携带者(PLWH)]的慢性疼痛管理。我建议 三个研究目标：1)了解与太极相关的感知途径、障碍、促进者和好处 对于艾滋病毒患者的慢性疼痛，将使用公共卫生研究所进行深入的定性访谈(N≈12-18) 和提供者(N≈6-10)在免疫中心；2)优化太极干预招募材料和 根据定性研究中获得的信息确定实施干预的最佳形式；以及3) 研究太极治疗长沙湾医院慢性疼痛的可行性和可接受性，我们会进行 气功/太极拳简易组与健康教育对照组的随机先导研究(N=40)。

PROJECT SUMMARY/ABSTRACT Candidate. I am excited to submit this application to NCCIH for a K23 Award. To date, I have received quality training as a scientist-practitioner in clinical health psychology, emphasizing research with HIV populations. To become an independent investigator with a research program focused on the use of mind-body interventions to manage chronic conditions, I require additional training in intervention design, implementation, and evaluation. Training Plan. My training goals for this K23 award include: 1) extend my knowledge of mind-body interventions for chronic pain management; 2) develop expertise regarding treatment for adults living with HIV and chronic pain; 3) cultivate advanced skills in clinical trial methods; 4) develop, implement, and evaluate a pilot trial of Tai Chi for chronic pain management among persons living with HIV; and 5) continue my professional development toward a successful career as an independently-funded investigator. Environment. During the award period, I will be an Assistant Professor in the Department of Psychiatry and Human Behavior (DPHB) at Brown University and Research Scientist at the Centers for Behavioral and Preventive Medicine (CBPM) of The Miriam Hospital. DPHB is among the top academic departments of psychiatry in the United States, with approximately 200 ongoing studies and $50 million in externally sponsored research. DPHB has an impressive track record of providing a suitable environment for the successful completion of K awards. CBPM provides an outstanding research environment that supports faculty in developing state-of-the-science, programmatic research by fostering a stimulating intellectual environment that encourages collaboration. Miriam Hospital is home to the Immunology Center, an urban HIV-clinic that provides comprehensive primary and specialty care for 1,700 HIV-infected patients, and is a major component of the Centers for AIDS Research (CFAR), a joint research effort between Brown and Boston Universities. Mentors. I have constructed an expert mentorship team, with leading scientists in the fields of mind-body research, behavioral interventions, HIV medicine, chronic pain management, and qualitative methods. Proposed Research. Consistent with the strategic priorities of NCCIH, the Office of AIDS Research, and NIH’s Federal Pain Research Strategy (FPRS), the proposed research addresses gaps in non-pharmacological chronic pain management in a neglected chronic pain group [i.e., people living with HIV (PLWH)]. I propose three research aims: 1) to understand perceived access, barriers, facilitators, and benefits related to Tai Chi for chronic pain among patients with HIV, in-depth qualitative interviews will be conducted with PLWH (N≈12-18) and providers (N≈6-10) at the Immunology Center; 2) optimize recruitment material for Tai Chi intervention and determine best format to deliver intervention based on information learned in qualitative study; and 3) to examine the feasibility and acceptability of Tai Chi for chronic pain management for PLWH, we will conduct a randomized pilot study (N = 40) of Qigong/Tai Chi Easy compared to a health education control group.