Tai Chi intervention to improve chronic pain management for adults with HIV

太极拳干预可改善成人艾滋病毒感染者的慢性疼痛管理

基本信息

批准号：
9910366
负责人：
Eugene M Dunne
金额：
$ 9.75万
依托单位：
MIRIAM HOSPITAL
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-04-15 至 2020-10-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9910366
关键词：
AIDS-Related Opportunistic Infections Acquired Immunodeficiency Syndrome Acute Pain Address Adult Advertisements Alcohol or Other Drugs use Applications Grants Award Behavior Behavior Therapy Behavioral Medicine Benchmarking Biological Boston Caring Chronic Clinic Clinical Clinical Research Clinical Trials Collaborations Communicable Diseases Complementary Medicine Control Groups Data Data Analyses Data Collection Development Disease Progression Environment Evaluation Fostering Funding Glean Goals Grant HIV HIV antiretroviral Health Health Care Costs Health Psychology Health education Home environment Hospitals Human Immunology Individual Injury Integrative Medicine Intervention Interview Joints K-Series Research Career Programs Knowledge Language Life Medical Medicine Mental Health Mentored Patient-Oriented Research Career Development Award Mentors Mentorship Meta-Analysis Methods Mind-Body Intervention Mind-Body Method NIH Office of AIDS Research Nervous system structure Nurses Opioid Pain Pain Research Pain management Patient Self-Report Patients Persons Pharmaceutical Preparations Physicians Pilot Projects Population Prevalence Preventive Medicine Provider Psychiatry Qi Gong Qualitative Methods Quality of life Randomized Randomized Controlled Trials Research Research Personnel Resources Schedule Science Scientist Self Management Series Stigmatization Tai Ji Tissues Training Transportation United States United States National Institutes of Health Universities Video Recording Virus Vulnerable Populations Withholding Treatment base body-mind career career development chronic pain chronic pain management chronic pain patient chronic painful condition comorbidity coping cost design disability efficacy testing evidence base experience faculty support immune function implementation research improved insight medical specialties neglect non-cancer chronic pain opioid misuse pain patient pain perception pain symptom pilot trial prescription opioid professor programs protocol development psychologic recruit response retention rate side effect skills therapy design

项目摘要

PROJECT SUMMARY/ABSTRACT Candidate. I am excited to submit this application to NCCIH for a K23 Award. To date, I have received quality training as a scientist-practitioner in clinical health psychology, emphasizing research with HIV populations. To become an independent investigator with a research program focused on the use of mind-body interventions to manage chronic conditions, I require additional training in intervention design, implementation, and evaluation. Training Plan. My training goals for this K23 award include: 1) extend my knowledge of mind-body interventions for chronic pain management; 2) develop expertise regarding treatment for adults living with HIV and chronic pain; 3) cultivate advanced skills in clinical trial methods; 4) develop, implement, and evaluate a pilot trial of Tai Chi for chronic pain management among persons living with HIV; and 5) continue my professional development toward a successful career as an independently-funded investigator. Environment. During the award period, I will be an Assistant Professor in the Department of Psychiatry and Human Behavior (DPHB) at Brown University and Research Scientist at the Centers for Behavioral and Preventive Medicine (CBPM) of The Miriam Hospital. DPHB is among the top academic departments of psychiatry in the United States, with approximately 200 ongoing studies and $50 million in externally sponsored research. DPHB has an impressive track record of providing a suitable environment for the successful completion of K awards. CBPM provides an outstanding research environment that supports faculty in developing state-of-the-science, programmatic research by fostering a stimulating intellectual environment that encourages collaboration. Miriam Hospital is home to the Immunology Center, an urban HIV-clinic that provides comprehensive primary and specialty care for 1,700 HIV-infected patients, and is a major component of the Centers for AIDS Research (CFAR), a joint research effort between Brown and Boston Universities. Mentors. I have constructed an expert mentorship team, with leading scientists in the fields of mind-body research, behavioral interventions, HIV medicine, chronic pain management, and qualitative methods. Proposed Research. Consistent with the strategic priorities of NCCIH, the Office of AIDS Research, and NIH’s Federal Pain Research Strategy (FPRS), the proposed research addresses gaps in non-pharmacological chronic pain management in a neglected chronic pain group [i.e., people living with HIV (PLWH)]. I propose three research aims: 1) to understand perceived access, barriers, facilitators, and benefits related to Tai Chi for chronic pain among patients with HIV, in-depth qualitative interviews will be conducted with PLWH (N≈12-18) and providers (N≈6-10) at the Immunology Center; 2) optimize recruitment material for Tai Chi intervention and determine best format to deliver intervention based on information learned in qualitative study; and 3) to examine the feasibility and acceptability of Tai Chi for chronic pain management for PLWH, we will conduct a randomized pilot study (N = 40) of Qigong/Tai Chi Easy compared to a health education control group.

项目摘要/摘要候选人。我很高兴将此申请提交NCCIH获得K23奖。迄今为止，我已经收到了质量作为临床健康心理学的科学家培训，强调了艾滋病毒群体的研究。到成为一名独立研究者，研究计划的研究计划着重于使用思维方式干预措施管理慢性条件，我需要在干预设计，实施和评估方面进行额外的培训。培训计划。我对K23奖的培训目标包括：1）扩展我对身心的知识慢性疼痛管理的干预措施； 2）开发有关艾滋病毒患者治疗的专业知识和慢性疼痛； 3）在临床试验方法中培养高级技能； 4）开发，实施和评估太极拳对艾滋病毒患者的慢性疼痛管理的试点试验； 5）继续我的作为独立资助的调查员成功职业生涯的专业发展。环境。在颁奖期间，我将担任精神病学系的助理教授布朗大学的人类行为（DPHB）和行为中心的研究科学家 Miriam医院的预防医学（CBPM）。 DPHB是顶级学术部门之一美国的精神病学，大约200次正在进行的研究和5000万美元的外部研究赞助研究。 DPHB具有令人印象深刻的记录，可为该环境提供合适的环境成功完成K奖。 CBPM提供了一个杰出的研究环境，以支持教师通过培养刺激的智力环境，在发展最先进的科学研究中这鼓励了合作。 Miriam医院是免疫学中心的所在地，这是一个城市的HIV-Clinic 为1,700名HIV感染患者提供全面的初级和专业护理，是主要组成部分艾滋病研究中心（CFAR）是布朗大学和波士顿大学之间的共同研究工作。导师。我已经建立了一个专业的精明团队研究，行为干预，艾滋病毒医学，慢性疼痛管理和定性方法。拟议的研究。与NCCIH的战略重点，艾滋病研究办公室以及 NIH的联邦疼痛研究策略（FPRS），拟议的研究解决了非药物的差距在一个负面发达的慢性疼痛组中，慢性疼痛治疗[即患有艾滋病毒（PLWH）]。我建议三个研究目的：1）了解感知到的访问，障碍，促进者以及与太极拳有关的福利 HIV患者的慢性疼痛将使用PLWH进行（N≈12-18）进行。以及免疫学中心的提供者（N≈6-10）； 2）优化用于太极干预和的招聘材料根据定性研究中学到的信息确定最佳格式以提供干预；和3）到检查太极拳对PLWH的慢性疼痛管理的可行性和可接受性，我们将进行一次与健康教育对照组相比，气功/太极拳的随机试验研究（n = 40）容易。