Tai Chi intervention to improve chronic pain management for adults with HIV

项目概要/摘要 候选人我很高兴向NCCIH提交K23奖的申请。到目前为止，我已经收到了质量 作为临床健康心理学的科学家从业者接受培训，强调对艾滋病毒人群的研究。到 成为一名独立的调查员，其研究项目专注于使用身心干预， 如果我想管理慢性病，我需要在干预设计、实施和评估方面接受额外培训。 培训计划。我这次K23奖的培训目标包括：1）扩展我的身心知识 慢性疼痛管理的干预措施; 2）发展有关艾滋病毒感染者治疗的专业知识 和慢性疼痛; 3）培养临床试验方法的高级技能; 4）开发，实施和评估 在艾滋病毒感染者中进行太极拳治疗慢性疼痛的试验;以及5）继续我的 专业发展走向一个成功的职业生涯作为一个独立资助的调查。 环境在获奖期间，我将在精神病学系担任助理教授， 布朗大学的人类行为（DPHB）和行为和 Miriam医院的预防医学（CBPM）DPHB是顶尖的学术部门之一， 精神病学在美国，大约有200个正在进行的研究和5000万美元的外部 赞助的研究。DPHB在提供合适的环境方面有着令人印象深刻的记录， 成功获得K奖。CBPM提供了一个优秀的研究环境，支持教师 在发展国家的科学，通过培养一个刺激的智力环境的方案研究 鼓励合作。米里亚姆医院是免疫学中心的所在地，免疫学中心是一家城市艾滋病诊所， 为1,700名艾滋病毒感染者提供全面的初级和专科护理， 艾滋病研究中心（CFAR），布朗大学和波士顿大学之间的联合研究工作。 导师我已经建立了一个专家指导团队，与领先的科学家在该领域的身心 研究，行为干预，艾滋病药物，慢性疼痛管理和定性方法。 提议的研究。根据国家儿童健康咨询委员会、艾滋病研究办公室和 根据NIH的联邦疼痛研究战略（FPRS），拟议的研究解决了非药物治疗的空白。 被忽视的慢性疼痛组中的慢性疼痛管理[即，艾滋病毒感染者（PLWH）。我提议 三个研究目标：1）了解感知的访问，障碍，促进者，和利益相关的太极拳， 艾滋病毒感染者的慢性疼痛，将与PLWH（N 12-18）进行深入的定性访谈 和提供者（N 106 -10）在免疫学中心; 2）优化太极干预的招聘材料， 根据定性研究中获得的信息确定提供干预的最佳形式;以及3） 为研究太极拳治疗爱滋病病毒感染者慢性疼痛的可行性和可接受性，我们会进行一项 气功/太极容易的随机试点研究（N = 40）相比，健康教育对照组.

PROJECT SUMMARY/ABSTRACT Candidate. I am excited to submit this application to NCCIH for a K23 Award. To date, I have received quality training as a scientist-practitioner in clinical health psychology, emphasizing research with HIV populations. To become an independent investigator with a research program focused on the use of mind-body interventions to manage chronic conditions, I require additional training in intervention design, implementation, and evaluation. Training Plan. My training goals for this K23 award include: 1) extend my knowledge of mind-body interventions for chronic pain management; 2) develop expertise regarding treatment for adults living with HIV and chronic pain; 3) cultivate advanced skills in clinical trial methods; 4) develop, implement, and evaluate a pilot trial of Tai Chi for chronic pain management among persons living with HIV; and 5) continue my professional development toward a successful career as an independently-funded investigator. Environment. During the award period, I will be an Assistant Professor in the Department of Psychiatry and Human Behavior (DPHB) at Brown University and Research Scientist at the Centers for Behavioral and Preventive Medicine (CBPM) of The Miriam Hospital. DPHB is among the top academic departments of psychiatry in the United States, with approximately 200 ongoing studies and $50 million in externally sponsored research. DPHB has an impressive track record of providing a suitable environment for the successful completion of K awards. CBPM provides an outstanding research environment that supports faculty in developing state-of-the-science, programmatic research by fostering a stimulating intellectual environment that encourages collaboration. Miriam Hospital is home to the Immunology Center, an urban HIV-clinic that provides comprehensive primary and specialty care for 1,700 HIV-infected patients, and is a major component of the Centers for AIDS Research (CFAR), a joint research effort between Brown and Boston Universities. Mentors. I have constructed an expert mentorship team, with leading scientists in the fields of mind-body research, behavioral interventions, HIV medicine, chronic pain management, and qualitative methods. Proposed Research. Consistent with the strategic priorities of NCCIH, the Office of AIDS Research, and NIH’s Federal Pain Research Strategy (FPRS), the proposed research addresses gaps in non-pharmacological chronic pain management in a neglected chronic pain group [i.e., people living with HIV (PLWH)]. I propose three research aims: 1) to understand perceived access, barriers, facilitators, and benefits related to Tai Chi for chronic pain among patients with HIV, in-depth qualitative interviews will be conducted with PLWH (N≈12-18) and providers (N≈6-10) at the Immunology Center; 2) optimize recruitment material for Tai Chi intervention and determine best format to deliver intervention based on information learned in qualitative study; and 3) to examine the feasibility and acceptability of Tai Chi for chronic pain management for PLWH, we will conduct a randomized pilot study (N = 40) of Qigong/Tai Chi Easy compared to a health education control group.