The Administrative Core of Prefrontal Cortex, Cognition, and Speech Symptoms in Parkinson’s disease (PRECIS-PD)

帕金森病的前额皮质、认知和言语症状的管理核心 (PRECIS-PD)

• 批准号: 10283242
• 负责人: Nandakumar Narayanan
• 金额: $ 10.67万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-17 至 2023-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10283242
• 关键词: Address; Administrator; Archives; Benchmarking; Biometry; Budgets; Clinical; Clinical Sciences; Code; Cognition; Cognitive; Communication; Communication Research; Communities; Data; Data Analyses; Data Set; Ensure; Environment; Feedback; Fostering; Functional disorder; Funding; Future; General Population; Goals; Grant; Institutes; Iowa; Leadership; Link; National Institute of Neurological Disorders and Stroke; Neurology; Neurosciences; Parkinson Disease; Patients; Persons; Prefrontal Cortex; Preparation; Principal Investigator; Publications; Randomized; Reproducibility; Research; Research Design; Research Personnel; Research Project Grants; Speech; Symptoms; Translational Research; Universities; Vision; data analysis pipeline; data sharing; epidemiology study; experience; improved; innovation; meetings; member; neuroinformatics; neurophysiology; programs; relating to nervous system; synergism

Abstract The Administrative Core of Prefrontal Cortex, Cognition, and Speech Symptoms in Parkinson’s disease (PRECIS-PD) will facilitate new collaborative projects that will advance our understanding of the prefrontal cortex (PFC) in cognitive and speech dysfunction in Parkinson’s disease (PD). Led by Dr. Nandakumar Narayanan (Program Director/Principal Investigator), this core will provide the leadership, oversight, and project management that will form the organizational basis for the proposed Exploratory Grant, as well as for a future NINDS Udall Center P50 application. The Administrative Core will promote research integration and synergies across projects and cultivate communication among our researchers and our internal and external committees. The University of Iowa will provide funding for a dedicated and experienced Research Administrator to manage the proposed Exploratory Grant. These efforts will be heavily buttressed by the outstanding research organizations at UI, including the Department of Neurology, the Iowa Neuroscience Institute (INI), and the Institute for Clinical and Translational Sciences (ICTS). The Administrative Core will provide focus, leadership, and vision for PRECIS-PD, foster open and effective research communication, develop pipelines for data analysis and data sharing, and ensure our research is robust, rigorous, and reproducible. This Administrative Core will manage all P20 projects to collect innovative preliminary data towards supporting a future P50 application. Our focus will be on communication and organization around high-quality neurophysiological data, and on cultivating an environment of transformational discovery that will inspire meaningful impact in the lives of PD patients.

抽象的 帕金森氏病前额叶皮层，认知和语音症状的行政核心 （PRECIS-PD）将促进新的合作项目，以提高我们对 帕金森氏病（PD）的认知和语音功能障碍的前额叶皮层（PFC）。由博士领导 Nandakumar Narayanan（计划总监/首席研究员），该核心将提供领导 监督和项目管理将构成拟议探索的组织基础 赠款以及未来的Ninds Udall Center P50应用程序。行政核心将促进 研究整合和跨项目的协同作用，并在研究人员之间培养沟通 以及我们的内部和外部委员会。爱荷华大学将为专门的和 经验丰富的研究管理员管理拟议的探索赠款。这些努力将是 由UI的杰出研究组织大力支撑，包括 爱荷华州神经科学研究所（INI）神经病学和临床和转化科学研究所 （ICT）。 行政核心将为Precis-PD提供重点，领导和愿景，寄养开放和 有效的研究沟通，开发用于数据分析和数据共享的管道，并确保我们的 研究是强大，严格且可重复的。此行政核心将管理所有P20项目 收集创新的初步数据，以支持未来的P50应用程序。我们的重点会放在 围绕高质量神经生理数据的沟通和组织 变革性发现的环境将激发对PD患者生活的有意义影响。