Administrative Core

摘要：行政核心 美国印第安人和阿拉斯加原住民肝癌的管理核心及其差异(LI-CAD) P20方案将有助于通过以下方式优化P20项目和核心开展的发现工作 行政支助、加强沟通、数据传播和结构化监督。这个 行政核心将为以下小组及其之间提供指导和加强沟通： ·LI-CAD执行委员会 ·LI-CAD外部和内部咨询委员会 ·参与机构(华盛顿大学[华盛顿大学]；弗雷德·哈钦森癌症研究中心 阿拉斯加土著部落健康联盟；切罗基民族健康服务[CNHS]； 德克萨斯大学西南分校；熊本大学，日本) ·人工智能/人工智能领导委员会(ANTHC和CNHS) ·发现团队(研究项目；发展研究计划；生物信息库；生物统计学) ·教育和宣传小组(AI/AN宣传委员会、教育和会议委员会； 职业提升计划) ·国家卫生研究院(NIH)和国家癌症研究所(NCI)的代表 LI-CAD P20由多个实体的独特协作组成(图1)。来自两国的调查人员 实体已经在协作研究方面证明了以前的成功，并将在此计划中合作建立 基础设施，以开发高度创新、多产和有意义的发现计划，其目标是 是减少阿拉斯加原住民和美洲印第安人之间的肝癌预后差异。《核心》 有以下具体目标： 具体目标1：提供支持LI-CAD P20主要目标的组织结构和 促进人工智能/人工智能--适当的研究目标、社区参与和研究成果的传播 具体目标2：将LI-CAD P20与主办机构(UW、FHCRC、ANTHC、CNHS和 UTSW)以及ANTHC和CNHS的AI/AN部落和研究组织。 具体目标3：通过以下方式监督LI-CAD P20计划研究项目和核心 对所有P20项目活动进行系统和透明的评估，并准备过渡到P50孢子项目。

ABSTRACT: ADMINISTRATIVE CORE The Administrative Core of our Liver Cancer in American Indians and Alaska Natives and Disparities (Li-CAD) P20 program will serve to optimize the work of discovery conducted by the P20 Projects and Cores through administrative support, enhancement of communication, data dissemination and structured oversight. The Administrative Core will provide guidance and enhance communication for and between the following groups: • Li-CAD Executive Committee • Li-CAD External and Internal Advisory Boards • Participating Institutions (University of Washington [UW]; Fred Hutchinson Cancer Research Center [FHCRC]; Alaska Native Tribal Health Consortium [ANTHC]; Cherokee Nation Health Service [CNHS]; University of Texas Southwestern [UTSW]; Kumamoto University, Japan) • AI/AN Leadership Council (ANTHC and CNHS) • Discovery Team (Research Projects; Developmental Research Program; Biorepository; Biostatistics) • Education and Advocacy Team (AI/AN Advocacy Committee, Education and Conference Committee; Career Enhancement Program) • National Institutes of Health (NIH) and National Cancer Institute (NCI) representatives The Li-CAD P20 is comprised of a unique collaboration of multiple entities (Figure 1). Investigators from each entity have demonstrated prior success in collaborative research and will partner in this program to establish the infrastructure to develop a highly innovative, productive and significant program of discovery whose aim it is to reduce disparities in liver cancer outcomes among Alaska Native and American Indian people. The Core has the following Specific Aims: Specific Aim 1: To provide the organizational structure for supporting the key objectives of the Li-CAD P20 and to promote AI/AN-appropriate research objectives, community involvement and dissemination of findings Specific Aim 2: To integrate the Li-CAD P20 with the host institutions (UW, FHCRC, ANTHC, CNHS and UTSW) and AI/AN Tribal and Research organizations at ANTHC and CNHS. Specific Aim 3: To provide oversight for the Li-CAD P20 Program Research Projects and Cores through structured and transparent evaluation of all P20 Program activities and prepare the transition to P50 SPORE.