A Mobile Tai Chi Platform for Fall Prevention in Older Adults

项目摘要 最近的研究表明，基于免疫的干预措施具有很大的保护和恢复潜力。 老年人的认知功能。在这种背景下，太极拳获得了研究人员和临床医生的兴趣 因为它在同一活动中包含了身体、认知、社会和冥想的成分。等 多模式运动方式有望对老年人的执行力和整体认知能力产生积极影响 功能，包括注意力控制，计划，抑制反应和工作记忆。所以，太极拳- 的干预措施可以帮助研究人员和临床医生解决老年人的认知能力下降和痴呆症。 成年人了在这项拟议的研究中，我们将招募一小群年龄在65-85岁之间的老年人， 残疾，并要求他们参加为期12周的家庭太极计划。这项研究将依赖于 远程医疗系统，我们的团队最近开发的家长奖（#R42AG059491）的一部分。受试者将 在干预前和干预后使用一系列测试进行评估，以评估干预的影响 执行和整体认知功能，身体功能和生活质量。这组测试将包括， 作为主要的结果指标，连线测试（评估远程太极拳干预对 认知功能）和双任务步幅时间变异性（DSTV）测试（以评估远程太极拳的影响 综合身体和认知功能的干预）。此外，这组测试将包括， 次要结局指标，身体功能的标准评估，如定时起身和行走试验， 握力、老年人体力活动量表和活动特定平衡信心 (ABC)问卷将使用SF-12评估健康相关生活质量。抑郁症状会 用流行病学中心修订的抑郁量表进行评估。自我报告功能 能力将与日常生活的工具性活动进行评估。这些数据将在术前与术后进行比较。 干预后得出效应量估计值，并为未来更大规模的研究提供动力。

Project Summary Exercise-based interventions have been recently shown to have great potential for preserving and restoring cognitive function in older adults. In this context, Tai Chi has gained the interest of researchers and clinicians because it incorporates physical, cognitive, social, and meditative components within the same activity. Such multimodal exercise modality is expected to have a positive effect on older adults’ executive and global cognitive function, including attentional control, planning, response to inhibition, and working memory. Hence, Tai Chi- based interventions could help researchers and clinicians to address cognitive decline and dementia in older adults. In the proposed study, we will recruit a small cohort of older adults, 65-85 years of age, with mild cognitive impairments, and ask them to participate in a 12-week home-based Tai Chi program. The study will rely on a tele-health system that our team recently developed as part of the parent award (#R42AG059491). Subjects will be evaluated pre- and post-intervention using a battery of tests chosen to assess the impact of the intervention on executive and global cognitive function, physical function, and quality of life. This battery of tests will include, as primary outcome measures, the Trail Making Test (to assess the impact of the tele-Tai Chi intervention on cognitive function) and the Dual task Stride Time Variability (DSTV) test (to assess the impact of the tele-Tai Chi intervention on combined physical and cognitive function). In addition, this battery of tests will include, as secondary outcome measures, standard assessments of physical function such as the Timed Up-and-Go test, handgrip strength, the Physical Activity Scale for the Elderly, and the Activities Specific Balance Confidence (ABC) questionnaire. Health-related quality-of-life will be assessed using the SF-12. Depressive symptoms will be assessed with the Center of Epidemiology Studies-Depression Scale Revised. Self-reported functional capacity will be assessed with the Instrumental Activities of Daily Living. These data will be compared pre- vs. post-intervention to derive effect size estimates and power a future, larger scale study.