Core B - Training Core

项目总结/摘要 MDSRC培训核心的总体目标是增加经过严格培训的 科学能力强的研究人员能够维持生产基础科学，转化和/或临床 肌肉萎缩症的研究项目。为了实现这一中心目标，核心小组将确定和征聘 合格的基础科学和临床博士前和博士后候选人谁表现出真正的兴趣 在肌营养不良症的独立基础科学，转化和/或临床研究中的潜力。 将特别强调从任职人数不足的群体中征聘受训人员， 种族、民族、性别、社会经济地位和残疾。培训核心基金和相关配套基金 将支持至少三个博士前学员在MDSRC教师实验室在任何时候，加上至少一个 博士后研究生和一名临床实习生。 在UF和加州大学洛杉矶分校的培训核心将监督和协调培训活动的频谱， 核心和配套资金支持的学员以及博士前、博士后和临床研究员 在项目支持的研究人员实验室从事肌营养不良症研究的研究人员 在MDSRC。每位学员将根据其过去的培训情况制定个人发展计划， 他们的主要导师和论文委员会的建议。根据受训者的职业阶段， 个性化的计划可能包括结构化的教学计划、研讨会和指导性的资助写作 经验所有博士前学员将被要求在各自的机构，包括课程注册 肌肉健康和疾病，资助写作和负责任的研究行为。临床研究的受训人员将 此外，还必须参加与临床试验的设计和实施有关的课程。UF和UCLA 提供肌肉萎缩症的具体课程-肌肉萎缩症和肌病在UF和机制 和肌营养不良症的治疗。加州大学洛杉矶分校的课程是完全在线和提供给任何学生 整个加州系统和超越大学，UF课程录制将在春季完成 2021年，并提供给三个地点的学员。 培训核心将通过支持1）每年举办的培训生， 在UF和加州大学洛杉矶分校的研讨会，2）前往参加年度NCH/俄勒冈州立大学肌肉课程，并为那些参加 课程，学员介绍晚上从UF，加州大学洛杉矶分校和NU学员，3）前往目前在我们的 Wellstone Center aligned New Directions in Muscle Biology and Disease（肌肉生物学和疾病新方向） 会议此外，MDSRC中心将继续组织两次国际会议，重点是 肌肉健康和疾病-新方向会议，以及健康中的骨骼肌生物学进展 疾病会议。在新方向会议上，培训中心将举办一次培训生数据闪电战， 培训生在不同的Wellstone中心，以促进互动和数据共享。

Project Summary/Abstract The overall objective of the MDSRC Training Core is to increase the number of rigorously trained and scientifically competent researchers capable of sustaining productive basic science, translational and/or clinical research programs in muscular dystrophy. To meet this central objective, the core will identify and recruit qualified basic science and clinical predoctoral and postdoctoral candidates who demonstrate a genuine interest in, and potential for, independent basic science, translational and/or clinical research in muscular dystrophy. Particular emphasis will be placed on the recruitment of trainees from underrepresented groups with respect to race, ethnicity, gender, socio-economic status and disabilities. The Training Core and associated matching funds will support at least three predoctoral trainees in MDSRC faculty labs at any one time, plus at least one postdoctoral trainee and one clinical trainee. The Training Cores at UF and UCLA will oversee and coordinate a spectrum of training activities for trainees supported by the core and matching funds, as well as the predoctoral, postdoctoral and clinical fellow researchers engaged in muscular dystrophy research in the labs of researchers supported through the projects of the MDSRC. Each trainee will prepare an Individual Development Plan, based on their past training and recommendations from their primary mentor and thesis committee. Depending on the career stage of the trainee, the individualized plan may consist of a structured didactic program, seminars, and mentored grant writing experiences. All predoctoral trainees will be required to enroll in courses at their respective institutions that cover muscle health and disease, grant writing and responsible conduct of research. Trainees in clinical research will further be required to enroll in courses related to the design and conduct of clinical trials. Both UF and UCLA offer specific courses on muscular dystrophies - Muscular Dystrophy and Myopathies at UF and Mechanisms and Therapies for Muscular Dystrophies at UCLA. The UCLA course is fully online and available to any student across the University of California system and beyond, and the UF course recording will be complete in Spring 2021, and made available to trainees across the three sites. The Training Cores will further enhance the training environment by supporting 1) annual trainee hosted seminars at UF and UCLA, 2) travel to attend the Annual NCH/OSU Myology Course and, for those attending the course, a trainee presentation evening for trainees from UF, UCLA and NU and, 3) travel to present at our Wellstone Center aligned New Directions in Muscle Biology and Disease (New Directions) international conference. In addition, the MDSRC Center will continue to organize two international conferences focused on muscle health and disease – the New Directions Conference, and Advances in Skeletal Muscle Biology in Health & Disease Conference. At the New Directions Conference, the Training Core will host a Trainee Data Blitz for trainees across the different Wellstone Centers to facilitate interactions and data sharing.