Core B - Training Core

项目摘要/摘要MDSRC培训核心的总体目标是增加严格培训和科学能力的研究人员的数量，能够维持生产性基础科学，转化和/或临床研究计划在肌营养不良症。为了实现这一中心目标，核心将确定和招募合格的基础科学和临床博士前和博士后候选人谁表现出真正的兴趣，并有潜力，独立的基础科学，转化和/或临床研究肌营养不良症。将特别重视从在种族、族裔、性别、社会经济地位和残疾方面代表性不足的群体中征聘受训人员。培训核心和相关的配套资金将支持至少三名博士前学员在MDSRC教师实验室在任何时候，加上至少一名博士后学员和一名临床实习生。在UF和加州大学洛杉矶分校的培训核心将监督和协调培训活动的核心和配套资金支持的学员的频谱，以及从事肌肉萎缩症研究的研究人员的实验室通过MDSRC的项目支持的博士前，博士后和临床研究员。每个学员将根据他们过去的培训和他们的主要导师和论文委员会的建议准备一份个人发展计划。根据受训者的职业阶段，个性化计划可能包括结构化的教学计划，研讨会和指导的赠款写作经验。所有博士前学员将被要求在各自的机构，涵盖肌肉健康和疾病，赠款写作和负责任的研究行为的课程报名。临床研究的受训人员还将被要求参加与临床试验的设计和实施有关的课程。用友和加州大学洛杉矶分校都提供肌肉营养不良的具体课程-肌肉营养不良和肌病用友和机制和治疗肌肉营养不良在加州大学洛杉矶分校。加州大学洛杉矶分校的课程是完全在线，并提供给整个加州系统和超越大学的任何学生，UF课程录制将在2021年春季完成，并提供给学员在三个网站。培训核心将进一步加强培训环境，支持1）年度学员在UF和加州大学洛杉矶分校主办的研讨会，2）前往参加年度NCH/俄勒冈州立大学肌肉学课程，并为那些参加课程的学员，一个学员介绍晚上从UF，加州大学洛杉矶分校和NU和，3）前往我们的井石中心目前对齐肌肉生物学和疾病的新方向（新方向）国际会议。此外，MDSRC中心将继续组织两个专注于肌肉健康和疾病的国际会议-新方向会议和健康与疾病会议中的骨骼肌生物学进展。在新方向会议上，培训核心将为不同Wellstone中心的学员举办学员数据闪电战，以促进互动和数据共享。

Project Summary/Abstract The overall objective of the MDSRC Training Core is to increase the number of rigorously trained and scientifically competent researchers capable of sustaining productive basic science, translational and/or clinical research programs in muscular dystrophy. To meet this central objective, the core will identify and recruit qualified basic science and clinical predoctoral and postdoctoral candidates who demonstrate a genuine interest in, and potential for, independent basic science, translational and/or clinical research in muscular dystrophy. Particular emphasis will be placed on the recruitment of trainees from underrepresented groups with respect to race, ethnicity, gender, socio-economic status and disabilities. The Training Core and associated matching funds will support at least three predoctoral trainees in MDSRC faculty labs at any one time, plus at least one postdoctoral trainee and one clinical trainee. The Training Cores at UF and UCLA will oversee and coordinate a spectrum of training activities for trainees supported by the core and matching funds, as well as the predoctoral, postdoctoral and clinical fellow researchers engaged in muscular dystrophy research in the labs of researchers supported through the projects of the MDSRC. Each trainee will prepare an Individual Development Plan, based on their past training and recommendations from their primary mentor and thesis committee. Depending on the career stage of the trainee, the individualized plan may consist of a structured didactic program, seminars, and mentored grant writing experiences. All predoctoral trainees will be required to enroll in courses at their respective institutions that cover muscle health and disease, grant writing and responsible conduct of research. Trainees in clinical research will further be required to enroll in courses related to the design and conduct of clinical trials. Both UF and UCLA offer specific courses on muscular dystrophies - Muscular Dystrophy and Myopathies at UF and Mechanisms and Therapies for Muscular Dystrophies at UCLA. The UCLA course is fully online and available to any student across the University of California system and beyond, and the UF course recording will be complete in Spring 2021, and made available to trainees across the three sites. The Training Cores will further enhance the training environment by supporting 1) annual trainee hosted seminars at UF and UCLA, 2) travel to attend the Annual NCH/OSU Myology Course and, for those attending the course, a trainee presentation evening for trainees from UF, UCLA and NU and, 3) travel to present at our Wellstone Center aligned New Directions in Muscle Biology and Disease (New Directions) international conference. In addition, the MDSRC Center will continue to organize two international conferences focused on muscle health and disease – the New Directions Conference, and Advances in Skeletal Muscle Biology in Health & Disease Conference. At the New Directions Conference, the Training Core will host a Trainee Data Blitz for trainees across the different Wellstone Centers to facilitate interactions and data sharing.