Life Course Perspective on Alcohol and Drug Use Trajectories from Adolescence into Adulthood

摘要/摘要 青年时期是一个充满挑战的时期，专注于做出重要的决定，这些决定可能会促进或阻碍 在不同领域的独立性。种族多样性的选择研究（CHOICE-STRATA Study） 成人过渡期的酒精和其他药物使用）评估了酒精和其他药物（AOD）的使用和功能， 许多域（例如，社会、经济、健康），跨越10岁至24岁青年的13波数据 （R 01 AA 016577、R 01 AA 020883、R 01 AA 025848），12个波的平均保留率为84% 到目前为止完成，从18岁开始（第8-12波）91%。拟议的研究，STRATA-XP（扩展），提供 这是一个重要的机会，可以跟踪这一庞大的种族/民族多样化的群体进入青年期（年龄 25-28），一个独特的发展时期，很少有当代纵向研究的AOD使用。 此应用程序响应NOT-AA-20-017：酒精研究中的流行病学和预防，重点是 了解酒精使用、危险饮酒和酒精使用障碍的发展轨迹， 与酗酒的“成熟”有关。我们建议从25岁开始每年进行4次额外的调查- 28（N= 2，500），并解决以下目标：目标1a：确定酒精使用的轨迹（以及烟草， 大麻和其他毒品使用）从10岁到年轻的成年。1b.检查个别因素的影响（例如， 抵抗自我效能），同伴因素（例如，周围的同龄人谁使用的时间）和邻里因素（两者 主观和客观，包括酒精和大麻出口密度）对AOD使用轨迹。目标二： 研究AOD如何使用青春期和成年期的轨迹来预测年龄的结果 28在三个核心领域：1）风险行为（例如，AOD的使用和紊乱，危险性行为，犯罪），2） 健康相关的生活质量（例如，心理的、身体的、社会的），以及3）成人角色功能和转变（例如， 就业、关系和家庭组成、生活满意度）。目标3：检查成人角色如何运作 和过渡，如追求职业和养育子女，纵向预测随后的变化，在AOD使用 和其他危险行为，以及与健康相关的生活质量。目标4：提供 了解可能发生在整个种族/民族，性别和教育程度的潜力 气溶胶光学厚度轨迹及与这些轨迹相关的因素。继续这项工作将使该领域 通过更好地理解AOD的发展模式、前因和后果， 在今天的年轻人中使用，因为他们过渡到年轻的成年人。

Summary/Abstract Young adulthood is a challenging time focused on making important decisions that can either facilitate or hinder independence across a variety of domains. The CHOICE-STRATA Study (CHOICE STudy of Racial diversity in AOD use during the Transition to Adulthood) has assessed alcohol and other drug (AOD) use and functioning in numerous domains (e.g., social, economic, health) across 13 waves of data in youth from age 10 to age 24 (R01AA016577, R01AA020883, R01AA025848), with retention rates averaging 84% across the 12 waves completed to date, and 91% from age 18 (waves 8-12). The proposed study, STRATA-XP (eXPanded), provides an important opportunity to follow this large and racially/ethnically diverse cohort into young adulthood (ages 25-28), a unique developmental period for which there are few contemporary longitudinal studies of AOD use. This application responds to NOT-AA-20-017: Epidemiology and Prevention in Alcohol Research, focused on understanding the developmental trajectories of alcohol use, risky drinking, and alcohol use disorders and the correlates of "maturing out" of heavy drinking. We propose to conduct 4 additional annual surveys from age 25- 28 (N=2,500) and address the following aims: Aim 1a: Identify trajectories of alcohol use (as well as tobacco, cannabis, and other drug use) from age 10 into young adulthood. 1b.Examine effects of individual factors (e.g., resistance self-efficacy), peer factors (e.g., time spent around peers who use) and neighborhood factors (both subjective and objective, including alcohol and cannabis outlet density) on AOD use trajectories. Aim 2: Examine how AOD use trajectories across adolescence and emerging adulthood predict outcomes through age 28 in three core domains: 1) risk behaviors (e.g., AOD use and disorder, risky sexual behavior, delinquency), 2) health-related quality of life (e.g., mental, physical, social), and 3) adult role functioning and transitions (e.g., employment, relationships and family formation, life satisfaction). Aim 3:Examine how adult role functioning and transitions, such as pursuing a career and parenting, longitudinally predict subsequent changes in AOD use and other risk behaviors, as well as health-related quality of life, in young adulthood. Aim 4: Provide an understanding of potential across race/ethnicity, gender, and educational attainment that may occur across the AOD trajectories and the factors associated with these trajectories. Continuing this work will move the field forward by providing a better understanding of developmental patterns, antecedents, and consequences of AOD use among today's young people as they transition into young adulthood.