Function Assessment Core

摘要/摘要 保持晚年的行动能力，定义为安全和独立行走的能力，是维持 高质量的生活，是许多日常生活活动的关键，也是 保持身体独立。因此，工具的持续开发和标准化 能够可靠地评估身体功能和残疾状况对于解决日益增长的 随着老年人口的不断增加，世界各地的社会都将面临挑战。身体机能 评估核心寻求继续提供必要的基础设施，以执行标准化、有效和 肌肉骨骼损伤、身体功能和残疾的可靠测量 嵌入、支持或与波士顿OIAC相关的观察性研究和临床试验。 这一核心的领导层在过去的项目期内进行了广泛的合作，在 这些测量在老年人广泛的横断面和干预性研究中的应用 成人，并一直处于开发和改进新仪器和 评估身体功能和残疾领域的技术。 我们建议研究以下具体目标： 目标1：我们将为FAC支持的程序和活动提供一个有组织的基础设施 老龄化人类营养研究中心和布里格姆妇女医院运动实验室 生理和身体功能，并作为OAIC跨学科合作的焦点 开发、评估和应用新的和现有的工具和工具的调查人员 评估老年人的肌肉骨骼损伤、身体功能和残疾，以评估 功能促进疗法。 目标2：我们将提供直接测量和咨询服务，并协助提出建议 由OAIC主题支持的或与OAIC主题相关的需要采取措施的临床研究的发展 肌肉骨骼损伤、身体功能和/或残疾。所有核心服务将使用标准化的 用于评估肌肉功能和功能限制的设备和操作规程 人体研究，并将维持广泛的质量控制程序，包括：人员培训和 认证；设备维护；以及质量控制。 目标3：我们将开发新的和创新的方法来评估肌肉骨骼损伤，体检 老年人的功能和残疾。FAC还将支持旨在实现以下目标的创新发展项目 开发或进一步验证评估肌肉骨骼损伤、身体功能、 以及老年人的残疾。

SUMMARY / ABSTRACT Preserving late-life mobility, defined as the ability to walk safely and independently, is central to maintaining a high quality of life, is critical for the performance of many activities of daily living and is necessary for maintaining physical independence. Therefore, the continued development and standardization of tools that can reliably assess physical functioning and disability status will be important for addressing the growing challenge that societies worldwide will face with the expanding older population. The physical function assessment core seeks to continue to provide the necessary infrastructure to perform standardized, valid and reliable measures of musculoskeletal impairments, physical function, and disability across the spectrum of observational studies and clinical trials embedded within, supported by, or associated with the Boston-OIAC. The leadership of this core has collaborated extensively over the past project period, has unique experience in the application of these measurements across a wide range of cross-sectional and intervention studies in older adults, and has been on the leading edge of the development and refinement of new instruments and technologies to assess domains of physical function and disability. We propose to examine the following specific aims: Aim 1: We will provide an organized infrastructure for FAC-supported procedures and activities across Tufts’ Human Nutrition Research Center on Aging, and Brigham and Women’s Hospital Laboratory of Exercise Physiology and Physical Function and serve as focal point for interdisciplinary collaboration by OAIC investigators in the development, evaluation, and application of new and existing tools and instruments to assess musculoskeletal impairments, physical function, and disability in older adults to evaluate the efficacy of function promoting therapies. Aim 2: We will provide direct measurement and consultative services, as well as assist with proposal development for clinical studies supported by, or associated with, the theme of the OAIC that require measures of musculoskeletal impairments, physical function, and/or disability. All Core services will use standardized equipment and operating protocols for the assessment of muscle performance and functional limitations in human studies, and will maintain extensive quality control procedures including: personnel training and certification; equipment maintenance; and quality control. Aim 3: We will develop novel and innovative approaches to assess musculoskeletal impairments, physical function, and disability in older adults. The FAC will also support innovative developmental projects that seek to develop or further validate innovative approaches to assess musculoskeletal impairments, physical function, and disability in older adults.