NCTN Deep South Research Consortium

阿拉巴马大学伯明翰综合癌症中心 (UAB CCC) 拥有悠久的历史 参与国家癌症相关临床试验合作组的历史 计划。具体来说，UAB 是 GOG 的创始成员，并且一直是 RTOG、ECOG、ACRIN。 CALGB、NSABP 和 SWOG。 UAB CCC 是该协会的现任成员 ALLIANCE、ECOG-ACRIN、NRG 和 SWOG 合作团体。 UAB NCTN 深南 研究联盟 (DSRC) 目前是 NCI 的主要学术参与网站 国家临床试验网络 (NCTN) 计划，现提交此提案以继续 以此身份为 NCI 服务。我们打算继续作为科学领域的主要贡献者 美国尤其是美国 NCTN 项目的领导者和临床试验参与者 东南。为实现这一总体愿景，我们提出以下具体目标： 1) 进一步 加强现有 UAB CCC 科学领导层对 NCTN 合作小组的参与 相关临床和转化研究并开发下一代 NCTN UAB CCC 内的合作小组科学领导者，以及 2) 进一步完善临床试验 DSRC 内优化潜在合格癌症患者和患者应计的流程 有癌症风险参加 NCTN 合作组临床试验，以及 3) 进一步增加少数群体 NCTN 合作组试验的应计费用。我们在此提案中详细描述了 我们的 DSRC 合作小组科学和患者应计贡献和成就， 我们联盟的领导和组织结构，以及我们打算如何利用现有的 DSRC 基础设施可实现我们的目标。此外，我们还详细描述了我们的 初级研究员招募和指导计划。

The University of Alabama at Birmingham Comprehensive Cancer Center (UAB CCC) has a long history of participation within the nation's cancer related Clinical Trials Cooperative Group Program. Specifically, UAB was a founding member of the GOG, and has been a member of RTOG, ECOG, ACRIN. CALGB, NSABP, and SWOG. UAB CCC is a current member of the ALLIANCE, ECOG-ACRIN, NRG and SWOG cooperative groups. The UAB NCTN Deep South Research Consortium (DSRC) is currently a Lead Academic Participating Site in the NCI's National Clinical Trials Network (NCTN) Program, and now submits this proposal to continue to serve the NCI in this capacity. It is our intention to continue as a leading contributor of scientific leaders and clinical trial participants to the NCTN Program in the U.S. and particularly in the Southeast. To accomplish this overall vision, we propose the following specific aims: 1) To further enhance the involvement of existing UAB CCC scientific leadership in NCTN Cooperative Group related clinical and translational research and to develop the next generation of NCTN Cooperative group scientific leaders within the UAB CCC, and 2) To further refine a clinical trials process within the DSRC that optimizes accrual of potentially eligible cancer patients and patients at risk for cancer to NCTN Cooperative Group clinical trials, and 3) To further increase minority accrual to NCTN Cooperative Group trials. We include in this proposal a detailed description of our DSRC cooperative group scientific and patient accrual contributions and accomplishments, a leadership and organizational structure for our Consortium, and how we intend to utilize existing DSRC infrastructure to achieve our aims. Further, we also include a detailed description of our Junior Investigator Recruitment and Mentoring Program.