Iowa Cochlear Implant Clinical Research Center VII
爱荷华州人工耳蜗临床研究中心七
基本信息
- 批准号:10308170
- 负责人:
- 金额:$ 247.26万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:1985
- 资助国家:美国
- 起止时间:1985-09-09 至 2023-05-14
- 项目状态:已结题
- 来源:
- 关键词:18 year oldAcoustic NerveAcousticsAddressAdultAffectAmericanAuditoryAuditory PerceptionAuditory systemBehaviorBehavioralBrainClinical ResearchCochlear ImplantsCognitionCognitiveCommunicationCuesDataDetectionEEG-based imagingEarEcologyElectric StimulationElectroencephalographyElectrophysiology (science)EnvironmentEnvironmental Risk FactorEtiologyFrequenciesGoalsHearingHearing AidsHumanImplantIndividualIndividual DifferencesIowaLeadLearningLifeMapsMeasuresMediatingMethodologyNational Institute on Deafness and Other Communication DisordersNoiseOutcomeOutcome MeasureParticipantPatient CarePatientsPerceptionPeripheralPersonsPhysiologicalPositron-Emission TomographyPrincipal InvestigatorProcessQuality of lifeRegistriesRequest for ApplicationsResearchResearch Project GrantsResidual stateRunningSemanticsSocial InteractionSocializationSourceSpeechStructureSystemTechnologyTimeUnited States National Institutes of HealthVariantauditory processingbasecognitive neurosciencedensityexperiencegroup interventionhearing impairmenthearing preservationhearing rangeimprovedimproved outcomeindividual variationinsightintervention effectlanguage processinglexical processingnoise perceptionnormal hearingobject recognitionpreservationprogramsremediationspeech in noisespeech processingstatisticsweb site
项目摘要
Program Director/Principal Investigator (Last, First, Middle): Gantz, Bruce J.
PROJECT SUMMARY - OVERVIEW
Hearing loss is a pervasive problem and, according to statistics from the NIDCD/NIH website, it is estimated
that it affects nearly 37.5 million Americans aged 18 years and older. While remediation with hearing aids and
cochlear implants has assisted those with moderate to profound loss, noise interferes with the ability to
understand speech. Our research has identified the important advantage of combining acoustic+electric
speech processing (A+E) to facilitate improved hearing in noise. Application of A+E processing has improved
outcomes of cochlear implants in quiet and noise, but there is significant individual variability in outcome
measures among subjects. To address these issues, this application requests continuation of the Iowa
Cochlear Implant Clinical Research Center. In this proposal we will investigate hearing and auditory perception
using studies that explore the mechanisms of electrical, acoustic, and A+E hearing from the auditory periphery
to the cortex, including measures of cortical (re)organization and higher order language processing. Equally
important, we also explore human ecology—factors in the person and in the environment that can mediate or
impede successful communication and can be modified by A+E speech processing. Our overarching goal of
this competitive renewal is to apply basic and cognitive neuroscience methodologies to assist us in addressing
these fundamental questions about how individuals use both acoustic and electric auditory information. Four
research projects, Human Ecology, Peripheral Electrophysiology, Central Auditory Integration and Cognitive
Dynamics of Language Processing, an administrative and patient care/technical support cores are proposed.
The overall objectives are to examine the impact that A+E processing function has on real-life socialization,
cognition and quality of life issues, and to evaluate auditory processing from the periphery to cortical and
higher level processing. We plan to study 200 newly implanted adult subjects with A+E hearing preservation
implants, 50 subjects that use a hearing aid, 50 normal hearing subjects, and a combination of 300 previously
implanted subjects with A+E, bimodal or single CIs that participate in our research registry. The four research
projects are highly integrated and depend on data from each other to answer the experimental questions
proposed.
项目负责人/主要研究者(最后一位、第一位、中间一位):J. J. J.布鲁斯。
项目概要-概述
听力损失是一个普遍的问题,根据NIDCD/NIH网站的统计数据,
它影响了近3750万18岁及以上的美国人。助听器的选配
人工耳蜗已经帮助那些中度到重度损失的人,噪音干扰了他们的能力,
理解演讲。我们的研究已经确定了结合声学+电学的重要优势
语音处理(A+E),以促进改善噪音中的听力。A+E处理的应用有所改善
人工耳蜗植入在安静和噪音环境中的结果,但结果存在显着的个体差异
主体之间的措施。为了解决这些问题,本申请要求继续爱荷华州
髋关节植入物临床研究中心。在这个建议中,我们将研究听力和听觉感知
通过研究探索听觉周边的电、声和A+E听觉机制,
包括皮质(重组)组织和高阶语言处理的措施。同样
重要的是,我们还探讨了人类生态因素的人和环境,可以调解或
阻碍了成功的交流,并且可以通过A+E语音处理来修改。我们的首要目标是
这种竞争性的更新是应用基本的和认知神经科学的方法来帮助我们解决
这些基本问题是关于个体如何使用声学和电听觉信息的。四
研究项目,人类生态学,外周电生理学,中央听觉整合和认知
动态语言处理,行政和病人护理/技术支持的核心。
总体目标是检验A+E加工功能对现实社会化的影响,
认知和生活质量问题,并评估从外周到皮层的听觉处理,
更高层次的处理。我们计划研究200名新植入A+E听力保留的成年受试者
植入物,50名使用助听器的受试者,50名听力正常的受试者,以及300名先前使用助听器的受试者。
参与我们研究登记的A+E、双峰或单一CI的植入受试者。四项研究
项目高度集成,并依赖于彼此的数据来回答实验问题
提出了
项目成果
期刊论文数量(0)
专著数量(0)
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会议论文数量(0)
专利数量(0)
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Bruce Jay Gantz其他文献
Bruce Jay Gantz的其他文献
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{{ truncateString('Bruce Jay Gantz', 18)}}的其他基金
Patient Management, Signal Processing, and Technical Support
患者管理、信号处理和技术支持
- 批准号:
8072656 - 财政年份:2010
- 资助金额:
$ 247.26万 - 项目类别:
Patient Management, Signal Processing, and Technical Support
患者管理、信号处理和技术支持
- 批准号:
7619261 - 财政年份:2008
- 资助金额:
$ 247.26万 - 项目类别:
Patient Management, Signal Processing, and Technical Support
患者管理、信号处理和技术支持
- 批准号:
7424007 - 财政年份:2007
- 资助金额:
$ 247.26万 - 项目类别:
Patient Management, Signal Processing, and Technical Support
患者管理、信号处理和技术支持
- 批准号:
7269220 - 财政年份:2006
- 资助金额:
$ 247.26万 - 项目类别: