Inner Strength and Influencing Factors in Persons Newly Diagnosed with Mild Cognitive Impairment and their Family Care Partners

项目摘要/摘要： 个人国家研究服务奖(NRSA)申请的目的是提供 受过基本研究培训的申请者将成为一名专注于优势的独立调查员 对轻度认知障碍(MCI)患者的干预，特别是那些改善生活质量的干预 通过增强内心的力量来生活。此NRSA将确保申请人具备建立 对内在力量的概念性理解，培养启动道德计划的基础技能 对MCI患者的弱势群体及其家庭护理进行严格的独立研究 合作伙伴，并获得专业发展技能，在严格的学术环境中取得进步。这次培训将 在资源丰富的环境中进行，并由世界知名的咨询团队提供支持，非常适合 申请者的主题和培训计划。从她当护士的临床经验来看，应聘者有第一手经验。 了解将一个人的长处纳入其护理计划的重要性和必要性。 每五个60岁及以上的人中就有一个患有MCI。绝大多数针对人的干预措施 对于MCI，专注于最大限度地减少赤字，而不是增强实力来提高生活质量。这一差距是 由于文献中对MCI患者的优势描述不足。填补这一空白的一个机会 是从MCI患者的角度来描述内心的力量。内在力量的定义是 一个人在充满挑战的环境中积极前进的内在过程，并与改进有关 生活质量。患有癌症和心脏病等严重疾病的成年人可以很好地描述内心的力量，但 在MCI中不是很好的特征。这项研究建议通过以下目标来填补这一知识空白：1) 描述新诊断的MCI患者的内在力量体验，2)探索家庭如何 护理伙伴影响新诊断的MCI患者的内在力量体验，3)识别 影响新诊断MCI患者内在力量的外部因素。这项研究将使用现实主义者， 注重个体体验的定性方法论。这项研究建议使用主位 采用以语音为中心的分析方法对MCI患者及其 家庭护理伙伴。这项研究有可能提供关于人的内在力量的新知识。 并阐明影响因素和家庭护理伙伴的作用。这项拟议的研究与 NINR的战略计划，旨在改善像MCI这样患有慢性病的个人的生活质量，就像这项工作所做的那样 释放机会的潜力，以增强内心的力量，从而提高生活质量。通过铺设一个强大的 有了内在力量的基础知识，我们可以更好地设计干预措施，这些干预措施基于对 MCI患者和他们的护理伙伴。未来的实施研究有可能有一个 对生活质量有重大影响。

Project Summary/Abstract: The purpose of this individual National Research Service Award (NRSA) application is to provide the applicant with essential research training to become an independent investigator focusing on strengths-based interventions for people living with Mild Cognitive Impairment (MCI), specifically those that improve quality of life by enhancing inner strength. This NRSA will ensure that the applicant achieves competence in establishing a conceptual understanding of inner strength, develops foundational skills to commence a program of ethical and rigorous independent research with the vulnerable population of persons with MCI and their family care partners, and gains professional development skills to advance in a rigorous academic setting. This training will occur in a resource rich environment with support from a world-renowned advising team ideally suited to the applicant’s topic and training plan. From her clinical experience as a nurse, the applicant has first-hand knowledge of the importance of and need to incorporate a person’s strengths into their plan of care. One in five people age 60 and older are living with MCI. The vast majority of interventions for persons with MCI focus on minimizing deficits rather than augmenting strengths to improve quality of life. This gap is due to under-characterization of strengths of persons with MCI in the literature. One opportunity to fill this gap is to describe inner strength from the perspective of the person living with MCI. Inner strength is defined as one’s internal process of moving positively through challenging circumstances and is associated with improved quality of life. Inner strength is well described in adults with serious illnesses like cancer and heart disease but is not well characterized in MCI. This study proposes to fill this gap in knowledge through the following aims: 1) To describe the experience of inner strength in persons newly diagnosed with MCI, 2) To explore how family care partners impact the experience of inner strength for persons newly diagnosed with MCI, 3) To identify external factors that influence inner strength for persons newly diagnosed with MCI. This study will use realist, qualitative methodology to focus on the experience of the individual. This study proposes to use thematic analysis that employs voice-centered methods of analysis applied to interviews of persons with MCI and their family care partners. This study has the potential to provide new knowledge about inner strength in persons with MCI and elucidate influencing factors and the role of family care partners. The proposed study aligns with NINR’s strategic plan to improve quality of life for individuals with chronic conditions, like MCI, as this work has the potential to unlock opportunities to enhance inner strength and thereby quality of life. By laying a strong foundational knowledge of inner strength, we can better design interventions that are based in what matters to persons with MCI and their care partners. Future implementation research has the potential to have a significant impact for quality of life.