Mentoring Patient-Oriented Research to Prevent Injury in Older Adults

指导以患者为导向的研究以防止老年人受伤

• 批准号: 10312142
• 负责人: Sarah Dyer Berry
• 金额: $ 12.08万
• 依托单位: HEBREW REHABILITATION CENTER FOR AGED
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-12-15 至 2025-11-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10312142
• 关键词: Accidental Injury; Advisory Committees; Aging; Alzheimer' s Disease; Alzheimer' s disease related dementia; American; Anticoagulants; Antihypertensive Agents; Award; Benefits and Risks; Caring; Cause of Death; Characteristics; Clinical; Clinical Investigator; Clinical Trials; Competence; Data; Development; Discipline; Disease; Dislocations; Elderly; Emergency department visit; Exercise; Feedback; Fellowship; Fracture; Frail Elderly; Funding; Future; Genetic; Geriatrics; Goals; Grant; Health; Healthcare; Hip Fractures; Hospitalization; Hypoglycemic Agents; Ingestion; Injury; Institute of Medicine (U.S.); Intervention; Intracranial Hemorrhages; Investigation; K-Series Research Career Programs; Lead; Leadership; Link; Literature; Medical; Mentors; Mentorship; Mid-Career Clinical Scientist Award (K24); Multi-Institutional Clinical Trial; Nursing Homes; Observational Study; Operative Surgical Procedures; Osteoporosis; Overdose; Patients; Performance; Persons; Pharmaceutical Preparations; Physicians; Physiological; Reading; Reporting; Research; Research Personnel; Research Project Grants; Research Training; Resources; Risk Factors; Role; Scientific Inquiry; Scientist; Specialist; Surgical complication; Syndrome; Testing; Testosterone; Time; Training; Training Programs; Translational Research; Work; age related; attributable mortality; burnout; design; experience; fall injury; falls; feasibility trial; health care service utilization; implementation science; improved; interest; investigator training; large datasets; medical schools; modifiable risk; neglect; novel; older patient; older women; patient oriented; patient oriented research; prevent; programs; shared decision making; skills; success; trend; vehicular accident

There is a real shortage of clinicians trained in geriatric principles, with even fewer clinicians with geriatric competencies also trained in patient-oriented research. My overarching goal is to grow the field of young investigators properly trained in patient-oriented aging research, and to improve the health of frail, older adults through my research efforts focused on unintentional injury. For more than ten years I have had funding from the NIA to study injurious falls in frail, older adults, and for the past six years I have served as the Program Director for the Harvard Multicampus Geriatric Medicine Fellowship. The current proposal will capitalize on my strengths as an independent clinical investigator with expertise in injurious falls and program leader to enhance my capacity to mentor early investigators in aging research. The specific aims of the current proposal are to 1) conduct high-quality research on preventing unintentional injuries in frail, older adults that will serve as a platform to engage early investigators in patient-oriented aging research; 2) grow the number of well-trained investigators skilled in studying unintentional injury in older adults; and 3) enhance my skills to lead and mentor early clinical investigators by completing formal didactic training focused on implementation science and leadership. Ongoing funded research projects that could serve as a platform to engage research trainees include a large observational study to determine the risks and benefits of antihypertensive, antihyperglycemic, and anticoagulant drugs in older adults with Alzheimer’s Disease and Related Dementias (ADRD), as well as a feasibility trial to develop and implement an intervention to prevent injurious falls in older nursing home residents. Additionally I have conducted research and continue to collaborate with investigators using several large datasets that will serve as an excellent resource for trainees. Potential mentees will be identified from a pipeline of existing training programs at Harvard Medical School including the Geriatric Medicine Fellowship, Translational Research in Aging Programs (T32), and others. I will develop an individualized mentoring plan with all trainees, including the design of an original hypothesis-driven research project, plan for individualized and group mentorship, and opportunities for coursework/didactics to enhance research training. Finally, I will boost my own mentoring skills through 1) formal didactics and directed reading on implementation science; 2) directed reading/coursework on mentorship; 3) a leadership course; 4) a course on preventing burnout; and 5) additional coursework (e.g., introduction to genetics) to expand my scientific inquiry. A Senior Advisory panel will provide feedback on my performance as a mentor and leader. In summary, this Career Development Award will provide me with the practical experience and formal didactic training to expand my capacity as a researcher, leader, and mentor in patient-oriented research on unintentional injury, including patients with ADRD. At the end of this 5-year award, I will have equipped at least 18 early investigators in the study of unintentional injury, many of whom will enter the field of aging research.

有一个真实的短缺的临床医生在老年人的原则培训，甚至更少的临床医生与老年人 能力也在以病人为导向的研究培训。我的首要目标是发展年轻人的领域 研究人员在以病人为导向的老龄化研究中得到适当的培训，并改善体弱老年人的健康状况。 通过我对意外伤害的研究十多年来，我一直得到来自 NIA研究虚弱的老年人的伤害性福尔斯，在过去的六年里，我一直担任该计划 哈佛多校区老年医学奖学金主任。目前的提案将利用我的 作为一名具有伤害性福尔斯专业知识的独立临床研究者和项目负责人， 我在老龄化研究中指导早期研究者的能力。本提案的具体目标是：1） 进行高质量的研究，以防止身体虚弱的老年人意外伤害，这将作为一个 让早期研究人员参与以患者为导向的老龄化研究的平台; 2）增加训练有素的人员数量 熟练研究老年人意外伤害的调查人员; 3）提高我的领导和指导技能 通过完成以实施科学为重点的正式教学培训， 领导正在进行的资助研究项目，可作为吸引研究学员的平台 包括一项大型观察性研究，以确定抗高血压，抗高血糖， 和抗凝药物治疗老年阿尔茨海默病和相关痴呆症（ADRD），以及 制定和实施干预措施以预防老年疗养院中的伤害性福尔斯跌倒的可行性试验 居民此外，我还进行了研究，并继续与调查人员合作， 大型数据集，将作为学员的优秀资源。潜在的学员将从一个 哈佛医学院现有培训项目的管道，包括老年医学奖学金， 老龄化项目转化研究（T32）等。我会制定一个个性化的指导计划 与所有学员，包括设计一个原始的假设驱动的研究项目，计划个性化 和小组指导，以及课程/教学法的机会，以加强研究培训。最后要 通过1）正式的教学法和关于实施科学的指导性阅读来提高我自己的指导技能; 2） 指导性阅读/辅导课程; 3）领导力课程; 4）预防倦怠课程;以及5） 额外的课程作业（例如，遗传学导论（Introduction to Genetics）来扩展我的科学探究。高级咨询小组 将对我作为导师和领导者的表现提供反馈。总之，这个职业发展 该奖项将为我提供实践经验和正式的教学培训，以扩大我作为一个 研究人员，领导者，并在以病人为导向的研究无意中受伤，包括患者的导师 ADRD。在这个为期5年的奖励结束时，我将配备至少18名早期研究人员， 意外伤害，其中许多人将进入老龄化研究领域。