Mentoring Patient-Oriented Research to Prevent Injury in Older Adults

指导以患者为导向的研究以防止老年人受伤

• 批准号: 10532744
• 负责人: Sarah Dyer Berry
• 金额: $ 12.08万
• 依托单位: HEBREW REHABILITATION CENTER FOR AGED
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-12-15 至 2025-11-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10532744
• 关键词: Accidental Injury; Advisory Committees; Aging; Alzheimer' s disease patient; Alzheimer' s disease related dementia; American; Anticoagulants; Antihypertensive Agents; Award; Benefits and Risks; Caring; Cause of Death; Characteristics; Clinical; Clinical Investigator; Clinical Trials; Collaborations; Competence; Data; Development; Discipline; Dislocations; Elderly; Emergency department visit; Exercise; Feedback; Fellowship; Fracture; Funding; Future; Genetic; Geriatrics; Goals; Grant; Health; Healthcare; Hip Fractures; Hospitalization; Hypoglycemic Agents; Ingestion; Injury; Institute of Medicine (U.S.); Intervention; Intracranial Hemorrhages; Investigation; K-Series Research Career Programs; Lead; Leadership; Link; Literature; Medical; Mentors; Mentorship; Mid-Career Clinical Scientist Award (K24); Multi-Institutional Clinical Trial; Nursing Homes; Observational Study; Operative Surgical Procedures; Osteoporosis; Overdose; Patients; Performance; Persons; Pharmaceutical Preparations; Physicians; Physiological; Reading; Reporting; Research; Research Personnel; Research Project Grants; Research Training; Resources; Risk Factors; Role; Scientific Inquiry; Scientist; Specialist; Surgical complication; Syndrome; Testing; Testosterone; Time; Training; Training Programs; Translational Research; Work; age related; attributable mortality; burnout; career; design; experience; fall injury; falls; feasibility trial; health care service utilization; implementation science; improved; interest; investigator training; large datasets; medical schools; modifiable risk; neglect; novel; older patient; older women; patient oriented; patient oriented research; prevent; programs; shared decision making; skills; success; trend; vehicular accident

There is a real shortage of clinicians trained in geriatric principles, with even fewer clinicians with geriatric competencies also trained in patient-oriented research. My overarching goal is to grow the field of young investigators properly trained in patient-oriented aging research, and to improve the health of frail, older adults through my research efforts focused on unintentional injury. For more than ten years I have had funding from the NIA to study injurious falls in frail, older adults, and for the past six years I have served as the Program Director for the Harvard Multicampus Geriatric Medicine Fellowship. The current proposal will capitalize on my strengths as an independent clinical investigator with expertise in injurious falls and program leader to enhance my capacity to mentor early investigators in aging research. The specific aims of the current proposal are to 1) conduct high-quality research on preventing unintentional injuries in frail, older adults that will serve as a platform to engage early investigators in patient-oriented aging research; 2) grow the number of well-trained investigators skilled in studying unintentional injury in older adults; and 3) enhance my skills to lead and mentor early clinical investigators by completing formal didactic training focused on implementation science and leadership. Ongoing funded research projects that could serve as a platform to engage research trainees include a large observational study to determine the risks and benefits of antihypertensive, antihyperglycemic, and anticoagulant drugs in older adults with Alzheimer’s Disease and Related Dementias (ADRD), as well as a feasibility trial to develop and implement an intervention to prevent injurious falls in older nursing home residents. Additionally I have conducted research and continue to collaborate with investigators using several large datasets that will serve as an excellent resource for trainees. Potential mentees will be identified from a pipeline of existing training programs at Harvard Medical School including the Geriatric Medicine Fellowship, Translational Research in Aging Programs (T32), and others. I will develop an individualized mentoring plan with all trainees, including the design of an original hypothesis-driven research project, plan for individualized and group mentorship, and opportunities for coursework/didactics to enhance research training. Finally, I will boost my own mentoring skills through 1) formal didactics and directed reading on implementation science; 2) directed reading/coursework on mentorship; 3) a leadership course; 4) a course on preventing burnout; and 5) additional coursework (e.g., introduction to genetics) to expand my scientific inquiry. A Senior Advisory panel will provide feedback on my performance as a mentor and leader. In summary, this Career Development Award will provide me with the practical experience and formal didactic training to expand my capacity as a researcher, leader, and mentor in patient-oriented research on unintentional injury, including patients with ADRD. At the end of this 5-year award, I will have equipped at least 18 early investigators in the study of unintentional injury, many of whom will enter the field of aging research.

接受过老年病学原理培训的临床医生确实很短缺，接受过老年病学原理培训的临床医生就更少了。 还接受了以患者为导向的研究方面的能力培训。我的首要目标是拓展年轻人的领域 研究人员接受了以患者为导向的衰老研究方面的适当培训，并改善体弱老年人的健康 通过我的研究工作，重点关注意外伤害。十多年来，我一直得到来自以下机构的资助： NIA 致力于研究体弱老年人的跌倒伤害，在过去的六年里，我一直担任该项目的负责人 哈佛多校区老年医学奖学金主任。当前的提案将利用我的 作为独立临床研究者的优势，具有伤害性跌倒方面的专业知识和项目领导者的优势，以增强 我指导衰老研究早期研究者的能力。当前提案的具体目标是 1) 开展高质量研究，预防体弱老年人的意外伤害，这将作为 吸引早期研究人员参与以患者为导向的衰老研究的平台； 2）增加训练有素的人员数量 擅长研究老年人意外伤害的调查人员； 3）增强我的领导和指导技能 早期临床研究人员通过完成专注于实施科学和 领导。正在进行的资助研究项目可以作为吸引研究实习生的平台 包括一项大型观察性研究，以确定抗高血压、抗高血糖、 患有阿尔茨海默病和相关痴呆症 (ADRD) 的老年人服用抗凝药物，以及 制定和实施预防老年疗养院伤害性跌倒干预措施的可行性试验 居民。此外，我还进行了研究，并继续与研究人员合作，使用了多种方法 大型数据集将成为学员的绝佳资源。潜在的受训者将从中确定 哈佛医学院现有培训项目的管道，包括老年医学奖学金， 老龄化项目的转化研究（T32）等。我将制定个性化的指导计划 与所有学员一起设计一个原创的假设驱动的研究项目，制定个性化的计划 和小组指导，以及课程作业/教学的机会，以加强研究培训。最后，我会 通过以下方式提高我自己的指导技能：1）关于实施科学的正式教学和定向阅读； 2） 有关指导的定向阅读/课程作业； 3）领导力课程； 4）预防倦怠课程；和 5) 额外的课程作业（例如，遗传学导论）来扩展我的科学探究。高级顾问小组 将对我作为导师和领导者的表现提供反馈。综上所述，本职业发展 该奖项将为我提供实践经验和正式的教学培训，以扩展我作为一名 以患者为导向的意外伤害研究的研究员、领导者和导师，包括患有以下疾病的患者 ADRD。在这个 5 年奖励结束时，我将配备至少 18 名早期研究人员来研究 无意的伤害，其中许多人将进入衰老研究领域。