ACR Basic and Clinical Research Conference: Rheumatologic Complications of Emerging Viral Infections / SARS-CoV-2

项目摘要-摘要 美国流变学学院（ACR）一直是促进双向交流的领导者。 风湿病科学家和研究人员之间的前沿科学信息交流 通过其年度基础和临床研究会议。从历史上看，这些科学研讨会 在ACR年会召开之前，在会议现场进行。去年，根据 由于大流行病的限制，这些专题讨论会实际上是作为年会的一项后续活动举办的。 ACR年度会议ACR Convergence每年吸引超过15，000名与会者， 提供一个论坛，就研究、教育、病人护理、 实践管理和宣传问题。因为基础和临床研究会议是在... ACR Convergence的会议活动，ACR已经能够吸引著名的科学家和研究人员， 否则可能不会出席。 2021年，基础和临床研究会议将联合举行，以吸引科学家和研究人员 来自基础、临床和转化研究界。会议的名称将是 新发病毒感染的流变学并发症/ SARS-CoV-2。这一综合办法将侧重于 新出现的病毒感染，特别是与SARS-CoV-2有关的病毒感染。这种致命的全球流行病 为风湿病学家提供了大量的相关数据。流变学家不仅要面对 管理她/他自己的风湿性疾病患者的各种抗风湿治疗，但病毒，如 SARS-CoV-2是引发相当数量的人中的风湿性并发症的原因。 感染的人。流变学家在诊断和治疗这些疾病方面发挥着重要作用。 并发症此外，风湿病学家在许多正在使用的生物疗法方面拥有专业知识 治疗严重的SARS-CoV-2感染。分享来自病毒大流行的不断扩大的知识是很重要的 与风湿病学家谁是不可或缺的照顾感染者在世界各地。 临床研究会议将重点讨论COVID-19疫苗对人类健康的影响等主题。 免疫受损宿主、细胞因子风暴综合征和COVID-19的皮肤病学表现。基本 研究会议将探讨的主题，如自身抗体的1型干扰素和其他细胞因子，抗 磷脂抗体及其在合并症中的作用，以及COVID-19中的中性粒细胞失调和NET。 会议组织者包括兰迪·克伦博士，儿科和医学教授在大学， 亚拉巴马在伯明翰（UAB）和关节炎基金会，亚拉巴马章赋予主席在儿科 流变学Cron博士是儿科流变学和儿科 亚拉巴马儿童流变学奖学金计划;玛丽安娜卡普兰博士，NIAMS首席 系统性自身免疫分支。她也是NIAMS的副科学主任;和ACR委员会 研究（Kristine Kuhn博士，主席）。ACR研究委员会专注于研究和研究 在风湿病学的培训，并鼓励临床和卫生服务的研究组织医疗 和保健，因为它们可能影响风湿性疾病患者。库恩博士，主席，是副教授， 科罗拉多大学安舒茨医学院医学流变学。

Project Summary-Abstract The American College of Rheumatology (ACR) has been a leader in the effort to facilitate the bidirectional exchange of cutting-edge scientific information between scientists and investigators in rheumatic diseases through its annual Basic and Clinical Research Conferences. Historically, these scientific symposia have occurred immediately prior to the ACR annual meeting at the site of the meeting. This past year, based on the pandemic restrictions, these symposia were hosted virtually as a post-event to the annual meeting. The ACR annual meeting, ACR Convergence, attracts more than 15,000 attendees each year and is the principal mechanism for providing a forum for the exchange of ideas about research, education, patient care, practice management and advocacy issues. Because the Basic and Clinical Research Conferences are pre- meeting events for ACR Convergence, ACR has been able to attract renown scientists and investigators who may otherwise not have attended. For 2021, the Basic and Clinical Research Conferences will be held jointly to attract scientists and investigators from both the basic, clinical and translational research communities. The title of the conference will be Rheumatologic Complications of Emerging Viral Infections / SARS-CoV-2. This combined approach will focus on emerging viral infections, especially as they relate to SARS-CoV-2. This deadly global pandemic has provided an enormous influx of data relevant to rheumatologists. Not only is the rheumatologist confronted with managing her/his own patients with rheumatic diseases on various anti-rheumatic therapies, but viruses like SARS-CoV-2 are responsible for triggering rheumatologic complications among a substantial number of infected individuals. Rheumatologists have an important role to play in diagnosing and treating these complications. Moreover, rheumatologists have expertise in many of the biologic therapeutics being employed to treat severe SARS-CoV-2 infections. Ever expanding knowledge from viral pandemics is important to share with rheumatologists who are integral to the care of infected individuals worldwide. Clinical research sessions will focus on topics such as the impact of COVID-19 vaccines for immunocompromised hosts, cytokine storm syndrome, and dermatologic manifestations of COVID-19. Basic research sessions will explore topics such as auto-antibodies to type 1 interferon and other cytokines, anti- phospholipid antibodies and their role in comorbidities, and neutrophil dysregulation and NETs in COVID-19. The conference organizers include Dr. Randy Cron, Professor of Pediatrics and Medicine at the University of Alabama at Birmingham (UAB) and the Arthritis Foundation, Alabama chapter endowed chair in Pediatric Rheumatology. Dr. Cron is the Director of the Division of Pediatric Rheumatology and the Pediatric Rheumatology Fellowship Program at Children's of Alabama; Dr. Mariana Kaplan, NIAMS Chief of the Systemic Autoimmunity Branch. She is also Deputy Scientific Director at NIAMS; and ACR Committee on Research (Dr. Kristine Kuhn, Chair). The ACR Committee on Research focuses on research and research training in rheumatology and encourages clinical and health services research on the organization of medical and health care as they may affect patients with rheumatic diseases. Dr. Kuhn, Chair, is Associate Professor, Medicine-Rheumatology at the University of Colorado Anschutz Medical Campus.