Research Training in Rheumatology

项目摘要 这个T32计划的主要目标是提供在发病机制的优秀研究培训， 风湿性和自身免疫性疾病的个人在几个关键水平的职业发展（医疗 学生、博士前研究生和博士后MD和PhD研究员）。长期的科学 丹佛在基础、转化和临床研究以及卫生服务和成果方面的机会 研究，提供一个高度支持的环境，以促进这一培训计划的广泛目标。新 发达的项目增加了对研究疾病的重视，这些疾病在代表性不足的国家更为普遍。 少数民族人口，以及招募这些群体的成员进入学术途径。这些努力将 再加上NIH资助的科罗拉多临床研究所提供的长期创新项目， 转化科学研究所（CCTSI），其临床研究培训计划和正式的教学 为MD和PhD学员提供临床研究培训，以增加机会并积极影响我们的T32 程序.此外，>20研究生院博士课程提供大量的正式培训，以及 为对基础研究感兴趣的学员提供知识和实验室资源。广泛的指导和 在负责任的研究和科学严谨的行为教育计划继续提高质量， 培训经验。此外，NIH资助的自身免疫预防中心的持续支持， 风湿性关节炎病因学研究（SERA），一个迅速扩大的科罗拉多中心， 个性化医疗，脊柱关节炎发病机制和预防方面的新项目， 科罗拉多公共卫生学院进一步促进了全面的培训环境。培训计划 将继续在医学教授迈克尔·霍勒斯博士的指导下进行这一竞争性更新， 免疫学和流变学部门负责人。Holers博士将与执行官密切合作 委员会和联合主任克里斯蒂库恩博士。30名参与教师将做出贡献。值得注意的是， 基于Rob博士开发的新儿科流变学培训计划的机会 Fuhlbrigge和两年的成功研究生产力的研究员之一，通过资助， 包括唐氏综合征T32补充，支持是要求从三个扩大到四个博士后 研究员每年。每年继续支助两名医科学生和两名博士前研究生 要求。医学院和医学系的课程包括研究密集型课程 这为积极性很高医科学生短期受训者以及参与的个人提供了机会 医学科学家和医师科学家培训计划。该计划的主要标准是 将继续受到评判的是学术研究人员的成功发展，他们推动基础和临床研究， 改善风湿性和自身免疫性疾病患者健康所需的研究进展。 本次T32的领导希望有机会继续支持他们的学员。

Project Summary The primary goal of this T32 program is to provide outstanding research training in the pathogenesis of rheumatic and autoimmune diseases for individuals at several key levels of career development (medical student, predoctoral graduate student and postdoctoral MD and PhD fellow). The longstanding scientific opportunities in Denver in basic, translational and clinical research, as well as health services and outcomes research, provide a highly supportive environment to promote the broad goals of this training program. Newly developed programs have increased the emphasis on studying diseases more prevalent in under-represented minority populations as well as recruiting members of these groups into academic pathways. These efforts join together with longstanding innovation programs available through the NIH-funded Colorado Clinical and Translational Sciences Institute (CCTSI), with its Clinical Research Training Program and formal didactic training in clinical investigation for MD and PhD trainees, to increase opportunities and positively affect our T32 program. In addition, >20 Graduate School PhD programs provide substantial formal training as well as intellectual and laboratory resources for trainees interested in basic research. Extensive mentoring and educational programs in responsible conduct of research and scientific rigor continue to enhance the quality of the training experiences. Additionally, the ongoing support of the NIH-funded Autoimmunity Prevention Center, the Studies of the Etiology of Rheumatoid Arthritis (SERA), a rapidly expanding Colorado Center for Personalized Medicine, newly established programs in spondyloarthritis pathogenesis and prevention, and the Colorado School of Public Health further facilitate a comprehensive training environment. The training program will remain for this competing renewal under the direction of Dr. Michael Holers, Professor of Medicine and Immunology and Head of the Division of Rheumatology. Dr. Holers will work closely with an Executive Committee and Co-Director Dr. Kristi Kuhn. Thirty Participating Faculty Members will contribute. Notably, based on opportunities through development of a new Pediatric Rheumatology training program by Dr. Rob Fuhlbrigge and two years of successful research productivity by one of those fellows funded through an INCLUDE Down Syndrome T32 supplement, support is requested to expand from three to four postdoctoral fellows per year. Continued support for two medical students and two pre-doctoral graduate students per year is requested. The curriculum for the School and Department of Medicine includes research-intensive programs that provide access to highly motivated medical student short term trainees as well as individuals participating in the Medical Scientist and Physician Scientist Training Programs. The primary criteria by which the program will continue to be judged is the successful development of academic investigators who drive basic and clinical research advances necessary to improve the health of patients with rheumatic and autoimmune diseases. Leadership of this T32 hope to have the opportunity to continue support for their trainees.