TRIP: Training in Translational Protocols for Minimal Invasive Diagnosis and Therapy in Pancreatico-biliary Cancers

该项目的总体目标是加强正在扩大的国家之一罗马尼亚卡罗尔·达维拉·布加勒斯特医学和药学大学（UMFCD）与欧盟一级的两个国际领先对手（H区-丹麦的哥本哈根大学医院和英国的伦敦大学学院）的战略伙伴关系。加强这些机构之间的网络活动，并结合它们在胰胆道疾病微创内窥镜干预领域的技能和能力。需要以培训和教育微创内窥镜介入领域的早期研究人员（ESR）的形式转化专门知识，以提高联合医疗和治疗中心及其临床附属医院创新服务的数量和质量。该提案是该联盟合作伙伴长期合作和联合多中心研究项目的结果。因此，在过去的20年里，在微创内窥镜手术领域有一个持续的临床研究活动，由各种国家和国际资助的主要人员参与了TRIP提案。TRIP提案的关键wp之一是一个研究项目的多中心方案，该项目研究来自内镜超声引导细针活检（EUS-FNB）标本的胰腺类器官培养物，并随后进行药物分型，用于胰腺癌患者的个性化治疗。因此，项目合作伙伴将把他们的专业知识转让给联合国人口基金，重点是博士生和研究人员。这种知识转移和能力建设将通过联合研究活动和学术合作、加强人员流动、教育和培训活动、讲习班、暑期学校和宣传活动来实现。最后，但并非最不重要的是，与贸易有关的知识产权计划的具体成果之一是提高了联合国生物多样性研究中心的研究管理单位

The overall aim of the project is to strengthen the strategic partnership of the University of Medicine and Pharmacy Carol Davila Bucharest (UMFCD), Romania, one of the Widening countries, with two internationally-leading counterparts at the EU level (Region H - Copenhagen University Hospital Herlev, Denmark and University College London, UK), to enhance networking activities among these institutions and to combine their skills and competences in the field of minimal invasive endoscopic interventions in pancreatico biliary diseases. Translated expertise, in the form of training and educating early-stage researchers (ESR) in the field of minimally invasive endoscopic interventionsis needed to increase the number and quality of innovative services at UMFCD and its clinical affiliated hospitals. The proposal is the result of a long-standing collaboration and joint multicentric research projects performed by the partners of the consortium. Thus, in the past 20 years, there was a sustained clinical research activity in the field of minimally invasive endoscopic procedures, supported by various national and international grants of the key persons involved in the TRIP proposal. One of the key WPs of the TRIP proposal is represented by a multicentre protocol for a research project on pancreatic organoid cultures derived from endoscopic ultrasound guided fine needle biopsy (EUS-FNB) specimens with consequent pharmacotyping, used for personalized therapy of pancreatic cancer patients. The project partners will thus transfer their expertise to UMFCD with an emphasis on PhD students and ESRs. This knowledge transfer and capacity building will be achieved through joint research activities and academic collaboration, enhanced staff mobility, education and training activities, workshops, summer schools, and dissemination events. Last, but not least, one of the concrete deliverables of the TRIP proposal is represented by the upgrading of the research management unit at UMFCD