TRIP: Training in Translational Protocols for Minimal Invasive Diagnosis and Therapy in Pancreatico-biliary Cancers

该项目的总体目标是加强罗马尼亚布加勒斯特卡罗尔·达维拉医学院(UMFCD)与欧盟层面的两个国际领先同行(丹麦赫列夫H区哥本哈根大学医院和英国伦敦大学学院)的战略伙伴关系，加强这些机构之间的联网活动，并结合它们在胰胆管疾病微创内窥镜干预领域的技能和能力。通过培训和教育微创内窥镜介入治疗领域的早期研究人员(ESR)的形式转换的专门知识，需要增加UMFCD及其临床附属医院的创新服务的数量和质量。该提案是该联盟的合作伙伴进行长期合作和联合多中心研究项目的结果。因此，在过去20年中，微创内窥镜手术领域有一项持续的临床研究活动，这得到了TRIP提案中涉及的关键人员的各种国家和国际赠款的支持。TRIP提案的关键WPS之一是一个多中心方案，该方案是一个研究项目的多中心方案，该方案来自于从内窥镜超声引导细针活检(EUS-FNB)标本中提取的胰腺器官培养，并随后进行药物分型，用于胰腺癌患者的个性化治疗。因此，项目合作伙伴将把他们的专业知识转移到UMFCD，重点是博士生和ESRS。这种知识转让和能力建设将通过联合研究活动和学术合作、加强工作人员流动、教育和培训活动、讲习班、暑期学校和传播活动来实现。最后但并非最不重要的是，旅行提议的具体可交付成果之一是升级了UMFCD的研究管理股

The overall aim of the project is to strengthen the strategic partnership of the University of Medicine and Pharmacy Carol Davila Bucharest (UMFCD), Romania, one of the Widening countries, with two internationally-leading counterparts at the EU level (Region H - Copenhagen University Hospital Herlev, Denmark and University College London, UK), to enhance networking activities among these institutions and to combine their skills and competences in the field of minimal invasive endoscopic interventions in pancreatico biliary diseases. Translated expertise, in the form of training and educating early-stage researchers (ESR) in the field of minimally invasive endoscopic interventionsis needed to increase the number and quality of innovative services at UMFCD and its clinical affiliated hospitals. The proposal is the result of a long-standing collaboration and joint multicentric research projects performed by the partners of the consortium. Thus, in the past 20 years, there was a sustained clinical research activity in the field of minimally invasive endoscopic procedures, supported by various national and international grants of the key persons involved in the TRIP proposal. One of the key WPs of the TRIP proposal is represented by a multicentre protocol for a research project on pancreatic organoid cultures derived from endoscopic ultrasound guided fine needle biopsy (EUS-FNB) specimens with consequent pharmacotyping, used for personalized therapy of pancreatic cancer patients. The project partners will thus transfer their expertise to UMFCD with an emphasis on PhD students and ESRs. This knowledge transfer and capacity building will be achieved through joint research activities and academic collaboration, enhanced staff mobility, education and training activities, workshops, summer schools, and dissemination events. Last, but not least, one of the concrete deliverables of the TRIP proposal is represented by the upgrading of the research management unit at UMFCD