Training the Next Generation of Psychiatrists-Scientists for Translational Research

培训下一代精神病学家-科学家进行转化研究

• 批准号: 10627452
• 负责人: ANTONIA S NEW
• 金额: $ 20.76万
• 依托单位: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-06-01 至 2028-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10627452
• 关键词: ABCB1 gene; Acceleration; Adult; Award; Back; Basic Science; Behavioral Sciences; Brain; Chronic; Clinic; Clinical; Clinical Research; Coupled; Data; Development Plans; Disease; Doctor of Philosophy; Education Projects; Ensure; Environmental Risk Factor; Explosion; Faculty; Foundations; Functional disorder; Funding; Genetic; Genomics; Goals; Grant; High Prevalence; Homelessness; Individual; Institution; Intervention; K-Series Research Career Programs; Lead; Leadership; Length; Mental disorders; Mentors; Mentorship; Mission; National Institute of Mental Health; Neurobiology; Neurosciences; Occupational; Outcome; Patient-Focused Outcomes; Physicians; Pilot Projects; Positioning Attribute; Poverty; Prevention; Prevention strategy; Process; Productivity; Program Description; Psychiatrist; Psychiatry; Recovery; Research; Research Personnel; Research Project Grants; Research Training; Residencies; Scientist; Structure; Substance abuse problem; Suicide; Time; Training; Translational Research; Travel; United States National Institutes of Health; Writing; brain abnormalities; career; career development; clinical training; cohort; critical period; design; diagnostic strategy; disability; education research; experience; family burden; hands on research; improved; medical specialties; meetings; neuropsychiatric disorder; next generation; physician-scientist training program; programs; recruit; skill acquisition; skills; social; success; symposium; translational physician; translational scientist

Psychiatry is a fertile medical specialty for translational research and physician-scientists bring a unique perspective to research through the blend of clinical and research experiences. Physician scientists are uniquely poised to bridge the gap between basic neurobiology and clinical disease and excel as leaders in translational research in psychiatry. However, the pipeline of physician scientists in psychiatry is in danger. The number and proportion of clinically trained physicians (MD or MD/PhD) who remain involved in research after residency has decreased substantially. Residency training is a critical period that can “make or break” a research career. Years of clinical training without adequate protected research time between pre-residency research training and residency graduation often result in a decline in research skills and psychiatry residency graduates often need to retrain in research skills, delaying the transition to independent research. Together with high indebtedness and low funding rates, this results in few psychiatrists applying for K or R01 Awards after residency training. Our proposed R25 program aims to train the next generation of psychiatrists-scientists during the critical period of psychiatry residency, to equip them to conduct translational research in psychiatry and accelerate the launch of independent research careers. Our program will help trainees acquire research skills and pilot data to obtain a career development (K) award. We will provide ample research protected time and coursework organized based on an Individual Development Plan. This training, coupled with outstanding mentoring and networking opportunities, grant writing seminars and an internal K award review process, will prepare promising physician scientists and help accelerate the launch of productive, independent careers in translational psychiatry research. Mount Sinai is the ideal place for this R25 program because of the strength of our Departments of Psychiatry, Neuroscience and Genetics/Genomics, which have been among the top departments nationwide in NIH funding over the past years, and have a wealth of potential mentors, including 123 NIH- funded PIs. Our exponential success in research accomplishments and funding is the result of a focused institutional effort to support physician-scientists and translational research. As an example of our commitment to recruitment, training and retention of physician-scientists, we have retained or recruited back over 50% of the graduates from our pilot physician-scientist training program.

精神病学是转化研究的肥沃医学专业，身体科学家带来了 通过临床和研究经验的融合来进行研究的独特观点。医师科学家 被中毒以弥合基本神经生物学和临床疾病之间的差距，并作为领导者出色 在精神病学转化研究中。但是，精神病学领域的物理科学家的管道正在 危险。临床培训的医生（MD或MD/PHD）的数量和比例仍然参与 在居住之后的研究中，居民大大减少。居住培训是一个关键时期 “使或打破”研究职业。多年的临床培训，没有足够的保护时间 在居住前研究培训和居住毕业之间，通常会导致研究下降 技能和精神病学居民毕业生通常需要在研究技能中进行重新培训，从而推迟了过渡到 独立研究。加上高昂的债务和低资金率，这很少 居住培训后，精神科医生申请K或R01奖。 我们提出的R25计划旨在培训下一代精神科医生在 精神病学居住的关键时期，使他们能够在精神病学领域进行转化研究 加快独立研究职业的推出。我们的计划将帮助学员获得研究 技能和试点数据获得职业发展（K）奖。我们将提供充分的研究保护 根据个人发展计划组织的时间和课程。这种培训，加上 杰出的心理和网络机会，赠款写作半货和内部K奖评论 过程，将准备承诺的医师科学家，并帮助加速产品的推出， 转化精神病学研究的独立职业。 西奈山是我们部门的实力，是该R25计划的理想场所 精神病学，神经科学和遗传学/基因组学，这是顶级部门之一 在过去的几年中，全国范围内的NIH资金获得了资金，并拥有大量潜在的导师，其中包括123名NIH- 资助的PI。我们在研究成就和资金方面的指数成功是集中的结果 机构努力支持身体科学家和翻译研究。作为我们的例子 致力于招募，培训和保留身体科学家，我们保留或招募 从我们的PILOT身体科学家培训计划中退回了50％以上的毕业生。