Training the Next Generation of Psychiatrists-Scientists for Translational Research

培训下一代精神病学家-科学家进行转化研究

• 批准号: 10627452
• 负责人: ANTONIA S NEW
• 金额: $ 20.76万
• 依托单位: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-06-01 至 2028-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10627452
• 关键词: ABCB1 gene; Acceleration; Adult; Award; Back; Basic Science; Behavioral Sciences; Brain; Chronic; Clinic; Clinical; Clinical Research; Coupled; Data; Development Plans; Disease; Doctor of Philosophy; Education Projects; Ensure; Environmental Risk Factor; Explosion; Faculty; Foundations; Functional disorder; Funding; Genetic; Genomics; Goals; Grant; High Prevalence; Homelessness; Individual; Institution; Intervention; K-Series Research Career Programs; Lead; Leadership; Length; Mental disorders; Mentors; Mentorship; Mission; National Institute of Mental Health; Neurobiology; Neurosciences; Occupational; Outcome; Patient-Focused Outcomes; Physicians; Pilot Projects; Positioning Attribute; Poverty; Prevention; Prevention strategy; Process; Productivity; Program Description; Psychiatrist; Psychiatry; Recovery; Research; Research Personnel; Research Project Grants; Research Training; Residencies; Scientist; Structure; Substance abuse problem; Suicide; Time; Training; Translational Research; Travel; United States National Institutes of Health; Writing; brain abnormalities; career; career development; clinical training; cohort; critical period; design; diagnostic strategy; disability; education research; experience; family burden; hands on research; improved; medical specialties; meetings; neuropsychiatric disorder; next generation; physician-scientist training program; programs; recruit; skill acquisition; skills; social; success; symposium; translational physician; translational scientist

Psychiatry is a fertile medical specialty for translational research and physician-scientists bring a unique perspective to research through the blend of clinical and research experiences. Physician scientists are uniquely poised to bridge the gap between basic neurobiology and clinical disease and excel as leaders in translational research in psychiatry. However, the pipeline of physician scientists in psychiatry is in danger. The number and proportion of clinically trained physicians (MD or MD/PhD) who remain involved in research after residency has decreased substantially. Residency training is a critical period that can “make or break” a research career. Years of clinical training without adequate protected research time between pre-residency research training and residency graduation often result in a decline in research skills and psychiatry residency graduates often need to retrain in research skills, delaying the transition to independent research. Together with high indebtedness and low funding rates, this results in few psychiatrists applying for K or R01 Awards after residency training. Our proposed R25 program aims to train the next generation of psychiatrists-scientists during the critical period of psychiatry residency, to equip them to conduct translational research in psychiatry and accelerate the launch of independent research careers. Our program will help trainees acquire research skills and pilot data to obtain a career development (K) award. We will provide ample research protected time and coursework organized based on an Individual Development Plan. This training, coupled with outstanding mentoring and networking opportunities, grant writing seminars and an internal K award review process, will prepare promising physician scientists and help accelerate the launch of productive, independent careers in translational psychiatry research. Mount Sinai is the ideal place for this R25 program because of the strength of our Departments of Psychiatry, Neuroscience and Genetics/Genomics, which have been among the top departments nationwide in NIH funding over the past years, and have a wealth of potential mentors, including 123 NIH- funded PIs. Our exponential success in research accomplishments and funding is the result of a focused institutional effort to support physician-scientists and translational research. As an example of our commitment to recruitment, training and retention of physician-scientists, we have retained or recruited back over 50% of the graduates from our pilot physician-scientist training program.

精神病学是转化研究的丰富医学专业，医师科学家带来了 通过结合临床和研究经验来进行独特的研究视角。医生科学家 具有独特的优势，可以弥合基础神经生物学和临床疾病之间的差距，并成为出色的领导者 在精神病学的转化研究中。然而，精神病学领域的医师科学家的管道正在建设中。 危险。仍然参与其中的经过临床培训的医生（医学博士或医学博士/博士）的数量和比例 住院医师实习后的研究大幅减少。住院医师培训是关键时期 “成就或毁掉”研究事业。多年的临床培训却没有足够的受保护的研究时间 住院医师前研究培训和住院医师毕业之间通常会导致研究下降 技能和精神病学住院医师实习毕业生通常需要接受研究技能的再培训，从而延迟了向 独立研究。再加上高负债和低融资率，这导致很少有 住院医师培训后申请 K 或 R01 奖的精神科医生。 我们提出的 R25 计划旨在在 精神病学住院医师实习的关键时期，使他们能够进行精神病学的转化研究 加快开展自主研究事业。我们的计划将帮助学员获得研究成果 技能和试点数据以获得职业发展（K）奖。我们将提供充足的研究保护 根据个人发展计划组织时间和课程作业。此次培训，结合 出色的指导和交流机会、资助写作研讨会和内部 K 奖评审 过程，将培养有前途的医师科学家，并帮助加速启动富有成效的、 转化精神病学研究的独立职业。 由于我们各部门的实力，西奈山是 R25 计划的理想地点 精神病学、神经科学和遗传学/基因组学一直位居顶尖院系之列 过去几年在全国范围内获得 NIH 资助，并拥有丰富的潜在导师，其中包括 123 名 NIH- 资助的 PI。我们在研究成果和资金方面取得的指数级成功是重点关注的结果 支持医师科学家和转化研究的机构努力。作为我们的例子 致力于招募、培训和保留医师科学家，我们保留或招募了 支持超过 50% 的试点医师科学家培训计划毕业生。