Training the Next Generation of Psychiatrists-Scientists for Translational Research

培训下一代精神病学家-科学家进行转化研究

• 批准号: 10627452
• 负责人: ANTONIA S NEW
• 金额: $ 20.76万
• 依托单位: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-06-01 至 2028-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10627452
• 关键词: ABCB1 gene; Acceleration; Adult; Award; Back; Basic Science; Behavioral Sciences; Brain; Chronic; Clinic; Clinical; Clinical Research; Coupled; Data; Development Plans; Disease; Doctor of Philosophy; Education Projects; Ensure; Environmental Risk Factor; Explosion; Faculty; Foundations; Functional disorder; Funding; Genetic; Genomics; Goals; Grant; High Prevalence; Homelessness; Individual; Institution; Intervention; K-Series Research Career Programs; Lead; Leadership; Length; Mental disorders; Mentors; Mentorship; Mission; National Institute of Mental Health; Neurobiology; Neurosciences; Occupational; Outcome; Patient-Focused Outcomes; Physicians; Pilot Projects; Positioning Attribute; Poverty; Prevention; Prevention strategy; Process; Productivity; Program Description; Psychiatrist; Psychiatry; Recovery; Research; Research Personnel; Research Project Grants; Research Training; Residencies; Scientist; Structure; Substance abuse problem; Suicide; Time; Training; Translational Research; Travel; United States National Institutes of Health; Writing; brain abnormalities; career; career development; clinical training; cohort; critical period; design; diagnostic strategy; disability; education research; experience; family burden; hands on research; improved; medical specialties; meetings; neuropsychiatric disorder; next generation; physician-scientist training program; programs; recruit; skill acquisition; skills; social; success; symposium; translational physician; translational scientist

Psychiatry is a fertile medical specialty for translational research and physician-scientists bring a unique perspective to research through the blend of clinical and research experiences. Physician scientists are uniquely poised to bridge the gap between basic neurobiology and clinical disease and excel as leaders in translational research in psychiatry. However, the pipeline of physician scientists in psychiatry is in danger. The number and proportion of clinically trained physicians (MD or MD/PhD) who remain involved in research after residency has decreased substantially. Residency training is a critical period that can “make or break” a research career. Years of clinical training without adequate protected research time between pre-residency research training and residency graduation often result in a decline in research skills and psychiatry residency graduates often need to retrain in research skills, delaying the transition to independent research. Together with high indebtedness and low funding rates, this results in few psychiatrists applying for K or R01 Awards after residency training. Our proposed R25 program aims to train the next generation of psychiatrists-scientists during the critical period of psychiatry residency, to equip them to conduct translational research in psychiatry and accelerate the launch of independent research careers. Our program will help trainees acquire research skills and pilot data to obtain a career development (K) award. We will provide ample research protected time and coursework organized based on an Individual Development Plan. This training, coupled with outstanding mentoring and networking opportunities, grant writing seminars and an internal K award review process, will prepare promising physician scientists and help accelerate the launch of productive, independent careers in translational psychiatry research. Mount Sinai is the ideal place for this R25 program because of the strength of our Departments of Psychiatry, Neuroscience and Genetics/Genomics, which have been among the top departments nationwide in NIH funding over the past years, and have a wealth of potential mentors, including 123 NIH- funded PIs. Our exponential success in research accomplishments and funding is the result of a focused institutional effort to support physician-scientists and translational research. As an example of our commitment to recruitment, training and retention of physician-scientists, we have retained or recruited back over 50% of the graduates from our pilot physician-scientist training program.

精神病学是转化研究和医生科学家带来了一个肥沃的医学专业， 通过临床和研究经验的融合，以独特的视角进行研究。医师科学家 在弥合基础神经生物学和临床疾病之间的差距方面， 精神病学的转化研究然而，精神病学的医生科学家的管道是在 危险继续参与的接受过临床培训的医生（医学博士或医学博士/博士）的数量和比例 在研究后，居住大幅减少。住院医师培训是一个关键时期， “成败在此一举”的研究生涯多年的临床培训，没有足够的保护研究时间 住院医师实习前研究培训和住院医师毕业之间的差距往往导致研究下降 技能和精神病学住院医师毕业生往往需要重新培训的研究技能，延迟过渡到 独立研究。再加上高负债率和低融资率， 在住院医师培训后申请K或R 01奖的精神科医生。 我们提出的R25计划旨在培养下一代精神科医生-科学家， 精神病学住院医师的关键时期，使他们能够进行精神病学的转化研究， 加快启动独立研究事业。我们的计划将帮助学员获得研究 技能和试点数据，以获得职业发展（K）奖。我们会提供充足的研究保护 根据个人发展计划组织的时间和课程。这种训练，加上 优秀的指导和网络机会，赠款写作研讨会和内部K奖审查 过程中，将准备有前途的医生科学家，并帮助加快推出生产， 在转化精神病学研究中的独立职业。 西奈山是这个R25计划的理想场所，因为我们部门的实力， 精神病学，神经科学和遗传学/基因组学，这一直是顶级部门之一 在过去的几年里，全国范围内的NIH资金，并有丰富的潜在导师，包括123 NIH- 资助的PI。我们在研究成就和资金方面的指数成功是专注于 机构努力支持医生-科学家和转化研究。作为我们的一个例子， 致力于招聘，培训和保留医生科学家，我们已经保留或招聘 超过50%的毕业生来自我们的试点医生科学家培训计划。