Training the Next Generation of Psychiatrists-Scientists for Translational Research

培训下一代精神病学家-科学家进行转化研究

• 批准号: 10627452
• 负责人: ANTONIA S NEW
• 金额: $ 20.76万
• 依托单位: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-06-01 至 2028-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10627452
• 关键词: ABCB1 gene; Acceleration; Adult; Award; Back; Basic Science; Behavioral Sciences; Brain; Chronic; Clinic; Clinical; Clinical Research; Coupled; Data; Development Plans; Disease; Doctor of Philosophy; Education Projects; Ensure; Environmental Risk Factor; Explosion; Faculty; Foundations; Functional disorder; Funding; Genetic; Genomics; Goals; Grant; High Prevalence; Homelessness; Individual; Institution; Intervention; K-Series Research Career Programs; Lead; Leadership; Length; Mental disorders; Mentors; Mentorship; Mission; National Institute of Mental Health; Neurobiology; Neurosciences; Occupational; Outcome; Patient-Focused Outcomes; Physicians; Pilot Projects; Positioning Attribute; Poverty; Prevention; Prevention strategy; Process; Productivity; Program Description; Psychiatrist; Psychiatry; Recovery; Research; Research Personnel; Research Project Grants; Research Training; Residencies; Scientist; Structure; Substance abuse problem; Suicide; Time; Training; Translational Research; Travel; United States National Institutes of Health; Writing; brain abnormalities; career; career development; clinical training; cohort; critical period; design; diagnostic strategy; disability; education research; experience; family burden; hands on research; improved; medical specialties; meetings; neuropsychiatric disorder; next generation; physician-scientist training program; programs; recruit; skill acquisition; skills; social; success; symposium; translational physician; translational scientist

Psychiatry is a fertile medical specialty for translational research and physician-scientists bring a unique perspective to research through the blend of clinical and research experiences. Physician scientists are uniquely poised to bridge the gap between basic neurobiology and clinical disease and excel as leaders in translational research in psychiatry. However, the pipeline of physician scientists in psychiatry is in danger. The number and proportion of clinically trained physicians (MD or MD/PhD) who remain involved in research after residency has decreased substantially. Residency training is a critical period that can “make or break” a research career. Years of clinical training without adequate protected research time between pre-residency research training and residency graduation often result in a decline in research skills and psychiatry residency graduates often need to retrain in research skills, delaying the transition to independent research. Together with high indebtedness and low funding rates, this results in few psychiatrists applying for K or R01 Awards after residency training. Our proposed R25 program aims to train the next generation of psychiatrists-scientists during the critical period of psychiatry residency, to equip them to conduct translational research in psychiatry and accelerate the launch of independent research careers. Our program will help trainees acquire research skills and pilot data to obtain a career development (K) award. We will provide ample research protected time and coursework organized based on an Individual Development Plan. This training, coupled with outstanding mentoring and networking opportunities, grant writing seminars and an internal K award review process, will prepare promising physician scientists and help accelerate the launch of productive, independent careers in translational psychiatry research. Mount Sinai is the ideal place for this R25 program because of the strength of our Departments of Psychiatry, Neuroscience and Genetics/Genomics, which have been among the top departments nationwide in NIH funding over the past years, and have a wealth of potential mentors, including 123 NIH- funded PIs. Our exponential success in research accomplishments and funding is the result of a focused institutional effort to support physician-scientists and translational research. As an example of our commitment to recruitment, training and retention of physician-scientists, we have retained or recruited back over 50% of the graduates from our pilot physician-scientist training program.

精神病学是翻译研究的肥沃医学专业，内科科学家带来了 通过临床和研究经验的融合，以独特的视角进行研究。内科科学家 以独特的姿态弥合基础神经生物学和临床疾病之间的差距，并作为领导者脱颖而出 在精神病学的翻译研究中。然而，精神病学的内科科学家的管道是在 危险。仍在参与的经过临床培训的医生(MD或MD/PhD)的数量和比例 在驻院后的研究中大幅减少。住院医师培训是一个关键时期，它可以 “成败在此一举”的研究事业。多年的临床培训，没有足够的保护研究时间 在实习前研究培训和住院医师毕业之间往往会导致研究的下降 技能和精神病学住院医师毕业生通常需要在研究技能方面进行再培训，从而推迟过渡到 独立研究。再加上高负债和低融资利率，这导致几乎没有 精神科医生在住院医师培训后申请K或R01奖项。 我们建议的R25计划旨在培训下一代精神病学家-科学家在 精神病学住院医师的关键时期，使他们能够进行精神病学和 加快开展自主研究事业。我们的计划将帮助学员获得研究 获得职业发展(K)奖的技能和试点数据。我们将提供充足的研究保护 根据个人发展计划安排时间和课程。这次培训，再加上 出色的指导和网络机会、助学金撰写研讨会和内部K奖评审 这一过程将培养有前途的内科科学家，并有助于加快推出富有成效的 从事翻译精神病学研究的独立职业。 西奈山是R25计划的理想地点，因为我们的部门实力雄厚 精神病学、神经科学和遗传学/基因组学，它们一直是最重要的系 在过去的几年里，他在全国范围内投入了NIH的资金，并拥有大量潜在的导师，包括123名NIH- 资助私募股权投资公司。我们在研究成就和资金方面的指数级成功是专注于 支持内科科学家和转化性研究的机构努力。作为我们的一个例子 致力于招聘、培训和留住内科科学家，我们已经留住或招聘了 超过50%的毕业生从我们的试点医生-科学家培训计划中回来。