Early Psychosocial Intervention and Child and Parent Cardiovascular Disease Risk

早期心理社会干预与儿童和家长心血管疾病风险

• 批准号: 10319565
• 负责人: Hannah Milena Caroline Schreier
• 金额: $ 46.53万
• 依托单位: PENNSYLVANIA STATE UNIVERSITY, THE
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-03-05 至 2024-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10319565
• 关键词: Adult; Affect; Age; Aggressive behavior; Atherosclerosis; Autopsy; Behavioral; Biological Markers; Birth Weight; Blood; Blood Pressure; Cardiovascular Diseases; Cessation of life; Child; Child Development; Child Mental Health; Child Rearing; Chronic; Climate; Collection; Conflict (Psychology); Data; Data Collection; Development; Environment; Event; Experimental Designs; Exposure to; Family; Family dynamics; Fetus; Foundations; Funding; Future; Health; Home; Home visitation; Individual; Infection; Inflammation; Inflammatory; Intervention; Intervention Studies; Intervention Trial; Life; Link; Longevity; Low Birth Weight Infant; Measures; Mediating; Mental Depression; Mental Health; Metabolic; Methods; Modeling; National Institute of Child Health and Human Development; Observational Study; Outcome; Parents; Participant; Pathway interactions; Pattern; Perinatal; Personal Satisfaction; Physiological; Plant Roots; Population; Prevention; Prevention strategy; Problem behavior; Psychological Stress; Psychosocial Factor; Psychosocial Influences; Questionnaires; Randomized Controlled Trials; Research; Risk; Risk Factors; Risk Marker; Role; Sampling; Scientist; Socioeconomic Status; Spottings; Stress; System; Testing; United States; base; cardiovascular disorder prevention; cardiovascular disorder risk; cardiovascular risk factor; cost; disease disparity; expectation; experience; experimental study; family influence; health disparity; improved; innovation; interpersonal conflict; intervention effect; maternal obesity; minimally invasive; novel; parental influence; perinatal intervention; physical conditioning; post intervention; psychosocial; randomized trial; socioeconomic adversity; socioeconomics; therapy design

Project Summary/Abstract The roots of cardiovascular disease (CVD), which is responsible for 32% of all deaths in the U.S., can be found during the early years, beginning perinatally. Although psychosocial interventions in populations across a wide age range have been shown to improve behavioral, mental health, and physical health outcomes, the development of effective early CVD prevention strategies and a deeper understanding of the ways in which psychosocial family factors interact to promote or reduce CVD risk are needed. The proposed project will build on the Family Foundations (FF) intervention, an ongoing NICHD-funded (PI: Feinberg, HD058529) randomized controlled trial of a perinatal intervention focused on coparenting, to examine the psychosocial pathways within the family that influence child and parent CVD risk. Additionally, we will examine potential intervention effects of FF on child and parent CVD risk. As part of the proposed project, we will augment the planned home visits (N = 294 families) which include questionnaire and family interaction data collection by adding the collection of baseline blood pressure, dried blood spot samples for the assessment of metabolic and inflammatory CVD risk markers, and important potential moderators of CVD risk. First, using these data and taking advantage of data available from three previous waves of data collection, we will develop models of interactive psychosocial influences on parent and child CVD risk. Specifically, this will include the consideration of child factors (e.g., behavioral problems), parent factors (e.g., depression), and family climate factors (e.g., parenting quality, family chaos and conflict), which we expect to interact and also contribute to CVD risk in unique ways. Second, we will test the extent to which these child, parent, and family factors mediate any effect of the FF intervention on CVD. Third, we will examine whether key external risk factors (parents’ lifetime socioeconomic status (SES) and adversity and children’s lifetime SES and birth weight) moderate any associations between child, parent, and family factors and CVD risk and whether they moderate main effects of the intervention on CVD risk. This research will be conducted by an interdisciplinary team of scientists who specialize in intervention research, psychosocial influences on health, minimally invasive field-based biomarker collection, and socioeconomic health disparities. The data resulting from this project will increase our understanding of the pathways through which the psychosocial family environment influences CVD risk and whether a psychosocial intervention can reduce CVD risk. By examining the moderating role of lifetime adversity and SES, the study will further inform future intervention research to unlock the potential of such interventions to reduce SES-based CVD disparities.

项目总结/文摘

项目成果

A perinatal coparenting intervention: Effects of a randomized trial on parent cardiometabolic risk and self-reported health.

围产期共同育儿干预：随机试验对父母心脏代谢风险和自我报告健康的影响。

• DOI: 10.1016/j.biopsycho.2023.108664
• 发表时间: 2023
• 期刊: Biological psychology
• 影响因子: 2.6
• 作者: Jones,EmilyJ;Feinberg,MarkE;Graham-Engeland,JenniferE;Jones,DamonE;Schreier,HannahMC
• 通讯作者: Schreier,HannahMC

Children's empathy moderates the association between perceived interparental conflict and child health.

儿童的同理心调节了感知到的父母间冲突与儿童健康之间的关联。

• DOI: 10.1016/j.bbi.2024.02.022
• 发表时间: 2024
• 期刊: Brain, behavior, and immunity
• 作者: Schreier,HannahMC;Feinberg,MarkE;Jones,DamonE;Ganguli,Aishwarya;Givens,Caitlin;Graham-Engeland,Jennifer
• 通讯作者: Graham-Engeland,Jennifer

Prospective Relations Between Prenatal Maternal Cortisol and Child Health Outcomes.

产前母亲皮质醇与儿童健康结果之间的前瞻性关系。

• DOI: 10.1097/psy.0000000000000705
• 发表时间: 2019
• 期刊: Psychosomatic medicine
• 影响因子: 3.3
• 作者: Roettger,MichaelE;Schreier,HannahMC;Feinberg,MarkE;Jones,DamonE
• 通讯作者: Jones,DamonE