Mentoring Researchers in Aging in Vulnerable Populations

项目摘要 库谢尔博士是加州大学旧金山分校医学系教授。 加州大学旧金山分校弱势人口中心(CVP)主任。作为普通内科医生和健康人员接受培训 服务研究员，Kushel博士在过去的不同级别的培训中指导了许多人 十年。她在建立一个蓬勃发展的研究项目的同时，也做到了这一点，该项目专注于弱势群体的老龄化 人口，特别关注不断增长的无家可归的老年人人口。她 目前由NIA资助希望之家研究，这是一项针对50岁及以上成年人的队列研究 她的团队自2013-2014年入学以来一直在跟踪研究入学时无家可归的人。在她最初的时候 K24获奖期间，她获得了额外的NIA资金，包括R01，用于检查家庭关系 无家可归的老年人和R34为以前无家可归的老年人开发高级护理计划材料 居住在永久性支持性住房中的成年人。她指导了39名学员，发表了45篇论文，内容广泛 多数，以导师为第一作者。随着K24奖项的续期，她将延长她的研究计划 通过增加对有无家可归经历的老年人的睡眠的关注，她继续努力指导 研究弱势群体老龄化的初级调查人员，并加倍努力指导受训人员 在研究中代表的背景不足。 这份K24更新建议的总体目标是：(1)使用希望之家的纵向数据，检查 个人(如健康状况)、行为(如药物使用)、社会(如人际关系)和 有无家可归经历的老年人睡眠不佳的环境(如住房状况和环境)；(2) 使用定性方法，检查老年人-无家可归者睡眠质量的障碍和促进者 (3)采用参与式设计，为无家可归者系统和住房提供者开发工具包，以促进 睡在无家可归的老年人身上。该奖项的指导目标包括增加库谢尔博士在 指导来自生物医学科学界历史上代表性不足的群体的研究人员。 K24将确保有足够的时间在库谢尔博士的研究中继续下一阶段，同时保护时间 致力于指导研究人员对弱势群体的老龄化研究。她设计了 互补的研究和指导计划创造指导和研究的协同效应。这个 建议的指导、研究和职业发展活动利用现有的基础设施、资源、 和由包括加州大学旧金山分校临床和翻译科学研究所(CTSI)在内的NIH提供的培训倡议， SF建筑基础设施通向多样性(BUILD)、MStar、国家临床医生学者计划和 加州大学旧金山分校的几个T32资助的研究奖学金包括初级保健研究和老龄化 研究奖学金。

Project Summary Dr. Kushel is a Professor in the Department of Medicine at the University of California, San Francisco (UCSF) and Director of the UCSF Center for Vulnerable Populations (CVP). Trained as a general internist and health services researcher, Dr. Kushel has mentored numerous individuals at various levels of training over the past decade. She has done this while building a thriving research program focused on aging in vulnerable populations, with a particular focus on the growing population of older adults experiencing homelessness. She is currently funded by the NIA to fund the HOPE HOME Study, a cohort study of adults who are 50 and older and homeless at study entry who her team has been following since enrollment in 2013-2014. During her initial K24 award period, she received additional NIA funding, including an R01 to examine family relationships in homeless older adults and an R34 to develop advance care planning materials for formerly homeless older adults living in permanent supportive housing. She mentored 39 trainees, and published 45 papers, the vast majority with mentees as first author. With the renewal of her K24 award, she will extend her research program by adding a focus on sleep in older adults with an experience of homelessness, continue her efforts to mentor junior investigators who study aging in vulnerable populations, and redouble her efforts to mentor trainees from backgrounds underrepresented in research. The overall aims of this K24 renewal proposal are: (1) Using HOPE HOME longitudinal data, examine the association of individual (e.g. health status), behaviors (e.g. substance use), social (e.g. relationships) and environmental (e.g. housing status and environment) with poor sleep in older homeless-experienced adults; (2) Using qualitative methods, examine barriers and facilitators of sleep quality in older-homeless experienced adults; (3) Using participatory design, develop a toolkit for homeless system and housing providers to promote sleep in older homeless adults. The mentoring goals of this award include increasing Dr. Kushel’s expertise in mentoring researchers from groups historically underrepresented in biomedical sciences. The K24 would insure sufficient time to pursue this next phase in Dr. Kushel's research while protecting time to devote to mentoring investigators in aging research for vulnerable populations. She has designed complementary research and mentoring plans to create a synergistic effect of mentoring and research. The proposed mentoring, research, and career development activities leverage existing infrastructure, resources, and training initiatives provided by NIH including the UCSF Clinical and Translational Science Institute (CTSI), SF Building Infrastructure Leading to Diversity (BUILD), MSTAR, the National Clinician Scholars Program and several of UCSF’s T32 supported research fellowships including the Primary Care Research and Aging Research Fellowships.