Rhode Island Hospital Injury Control Center for Biomedical Research Excellence (COBRE)

项目总结(总体) 伤害是1-44岁儿童死亡的主要原因，并导致3000多万起紧急事件 本部门每年访问1次。迫切需要更多的科学理解和战略来 与伤害流行作斗争，但与其他主要原因相比，伤害控制研究资金不足 死亡2，3.我们建议建立罗德岛医院伤害控制中心，用于生物医学研究 卓越(科布雷)。拟建的中心将是第一个也是唯一一个由NIH资助的科布雷研究中心 只专注于伤病控制。这项提议的目标是建立和建设一个科布雷中心，以支持 项目研究负责人的研究活动，以确保他们向独立资助的科学家过渡。 这一目标将通过以下具体目标来实现：1)建立核心(行政核心、伤害 控制数字化创新核心&伤害控制研究的实践和政策核心)需要发展和 维持一个关于伤害控制的专题多学科卓越研究中心，并2)支持遴选， 通过Cobre的研究研究和试点项目对早期职业教师进行指导和职业发展 学习计划。RIH伤害控制Cobre研究将针对整个伤害范围 在生命周期中与个人(儿童、新兴成年人和老年人)进行预防(初级、二级、三级) 成人)。最初的三名RPL是三名女性初级教员，他们有突出的潜力 对损伤科学研究的贡献：Leslie Brick，PhD，Elizabeth Goldberg，MD，SCM和Stephanie Ruest， 医学博士，最高时速。此外，一个试点项目方案将支持未来初级调查人员的研究建议，以 继续发展独立研究人员。这一有指导的试点计划将使早期工作得以开始 在重要的伤害控制主题上进行创新研究，并允许这些项目继续进行和推迟 在科布雷的研究项目或直接进展到独立的资金。Rih有一个强大的核心 伤害控制科学领域的资深研究人员；然而，如果我们这样做，我们的研究人员渠道将会枯竭 不能扩大和补充有能力进行伤害控制研究的人员。浅谈RIH损伤控制 Cobre将把初级调查人员、资深教员和咨询委员会成员聚集在一起，建立一个中心 它产生了高水平的独立研究人员，有能力处理和改善实质性的负担 伤害对人口健康有影响。它将被持续和严格地评估，考虑到恒定的 改进和准备我们的机构，以加快生产高质量的创新型伤害控制 研究和研究人员。

PROJECT SUMMARY (Overall) Injury is the leading cause of death for individuals 1-44 years of age and contributes to over 30 million emergency department visits annually1. There is a tremendous need for greater scientific understanding and strategies to combat the injury epidemic yet injury control research is underfunded compared to other leading causes of death2,3. We propose to establish the Rhode Island Hospital Injury Control Center for Biomedical Research Excellence (COBRE). The proposed Center would be the first and only NIH-funded COBRE research center to focus solely on injury control. The objective of this proposal is to establish and build a COBRE Center to support the research activities of project research leaders to ensure their transition to independently funded scientists. This objective will be met through the following specific aims: 1) establish the cores (Administrative Core, Injury Control Digital Innovation Core & Injury Control Research to Practice and Policy Core) needed to develop and sustain a thematic multidisciplinary center of research excellence on injury control and to 2) support the selection, mentorship, and career development of early career faculty through the COBRE’s research studies and a pilot study program. The RIH Injury Control COBRE research studies will target the entire spectrum of injury prevention (primary, secondary, tertiary) with individuals across the lifecycle (children, emerging adults and older adults). The three initial RPLs are three women junior faculty with outstanding potential to make significant contribution to injury science research: Leslie Brick, PhD, Elizabeth Goldberg, MD, ScM and Stephanie Ruest, MD, MPH. In addition, a pilot project program will support research proposals for future junior investigators to continue the growth of independent researchers. This mentored pilot program will allow early work to commence on important injury control topics with innovative research and allow those projects to proceed and become later Research Projects within the COBRE or to progress directly to independent funding. RIH has a strong core of senior researchers in the field of injury control science; however, our pipeline of researchers will run dry if we do not expand and replenish researchers capable of injury control research excellence. The RIH Injury Control COBRE will bring together junior investigators, senior faculty and advisory committee members to build a center which produces high level, independent researchers equipped to address and improve the substantial burden injury has on population health. It will be continuously and rigorously evaluated allowing for constant improvement and preparing our institution to accelerate its production of high-quality innovative injury control research and researchers.