Developmental Research Program
Developmental Research Program
批准号:
10333520
负责人:
Jason S. Lewis
金额:
$12.35万
依托单位国家:
美国
项目类别:
财政年份:
2022
资助国家:
美国
项目状态:
未结题
起止时间:
2022-09-20 至 2027-08-31
关键词:
AwardClinical TrialsCollaborationsCombined Modality TherapyDataDevelopmentDoctor of PhilosophyExtramural ActivitiesFacultyFundingGenomicsGoalsImmunotherapeutic agentIndividualInstitutionInvestigationIslet Cell TumorLeadershipMalignant neoplasm of pancreasMemorial Sloan-Kettering Cancer CenterOutcomePancreasParticipantPatient CarePeer ReviewPilot ProjectsProgram Research Project GrantsPublicationsRecording of previous eventsRequest for ProposalsResearchResearch PersonnelResearch SupportResourcesSeedsTranslational ResearchUnderrepresented PopulationsUnited States National Institutes of HealthUniversitiesVisionWomen&aposs Groupanticancer researchbasebiomarker developmentclinical careequity diversity and inclusioninnovationmedical schoolsnovel strategiespancreatic neoplasmpreferenceprogramsradiomicsstemsuccesstranslational cancer researchtranslational goal
中文摘要
项目总结/摘要- DRP
MSK胰腺孢子的发展研究计划(DRP)的目标是扩大
广泛的转化胰腺癌研究基础,并鼓励高度创新的研究
对胰腺癌的预后有很大的影响。减少灾害风险方案资金,加上机构资金,
我们每年将支持两个特殊的试点项目。我们将征求试点项目的建议书,
明确的翻译重点,并有可能最终影响胰腺癌患者的临床护理
肿瘤。具有胰腺癌研究史的研究者(MD、MD/PhD、DO或PhD)
任命在MSK或邻近机构,威尔康奈尔医学院和洛克菲勒大学,将
有资格申请。申请将由CEP/DRP遴选委员会进行同行评审,
由SPORE PI、DRP和CEP领导人组成,选择MSK部门和部门主席,以及
MSK平等、多样性和包容理事会的代表。最有价值的项目基于
将选定确定的审查标准。将优先考虑促进长期研究的项目
目标,并有很大的潜力成为完整的SPORE项目。我们将优先考虑提交的项目
并致力于促进多样性和加强参与
妇女和翻译研究中代表性不足的群体。DRP获奖者将完全访问SPORE
核心资源,将受益于SPORE调查团队的专业知识,并将积极参与
在孢子。DRP领导人将每六个月对DRP项目的科学进展进行一次评估。
DRP获奖者的长期成功指标包括原创研究的展示/出版,成功的
独立研究支持的竞争,成功开发和完成临床试验,
从DRP研究、建立新的合作以及学术界的机构认可
推广.在实现其转化目标方面取得重大进展的DRP项目将有资格获得
第二年的资金,并有可能被推广到完整的SPORE项目。
英文摘要
PROJECT SUMMARY/ABSTRACT – DRP
The goals of the Developmental Research Program (DRP) of the MSK Pancreas SPORE are to expand the
breadth of the translational pancreatic cancer research base and to encourage highly innovative investigations
that have major potential to impact pancreatic cancer outcomes. DRP funds, supplemented by institutional funds,
will allow us to support 2 exceptional pilot projects each year. We will request proposals for pilot projects with a
clear translational focus and with potential to ultimately impact clinical care of patients with pancreatic
neoplasms. Investigators (MD, MD/PhD, DO, or PhD) with a demonstrated history of pancreas cancer research
appointed at MSK or a neighboring institution, Weill Cornell Medical College and the Rockefeller University, will
be eligible to apply. Applications will be peer-reviewed by the CEP/DRP Selection Committee, which is
composed of the SPORE PIs, DRP and CEP Leaders, select MSK Departmental and Divisional Chairs, and
representatives from the MSK Equality, Diversity & Inclusion Council. The most meritorious projects based on
defined review criteria will be selected. Preference will be given to projects that advance the long-term research
goals of the SPORE and have high potential to become full SPORE projects. We will prioritize projects submitted
by early-stage investigators and are committed to promoting diversity and strengthening the participation of
women and underrepresented groups in translational research. DRP awardees will have full access to SPORE
Core resources, will benefit from the expertise of the SPORE investigative team, and will be active participants
in the SPORE. The scientific progress of DRP projects will be evaluated every six months by the DRP Leaders.
Long-term metrics of success for DRP awardees include presentation/publication of original research, successful
competition for independent research support, successful development and completion of clinical trials stemming
from DRP research, establishment of new collaborations, and institutional recognition by academic
promotion. DRP projects that make significant progress towards their translational goals will be eligible for a
second year of funding and have the potential to be promoted to full SPORE projects.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Developmental Research Program
-
批准号:10708758
-
项目类别:
-
资助金额:$11.08万
-
财政年份:2022
-
负责人:Jason S. Lewis
-
依托单位:
Annotating Cancer Biology through Non-Invasive Molecular Imaging
-
批准号:10471612
-
项目类别:
-
资助金额:$14.37万
-
财政年份:2019
-
负责人:Jason S. Lewis
-
依托单位:
Annotating Cancer Biology through Non-Invasive Molecular Imaging
-
批准号:10686347
-
项目类别:
-
资助金额:$105.6万
-
财政年份:2019
-
负责人:Jason S. Lewis
-
依托单位:
Annotating Cancer Biology through Non-Invasive Molecular Imaging
-
批准号:10249950
-
项目类别:
-
资助金额:$107.76万
-
财政年份:2019
-
负责人:Jason S. Lewis
-
依托单位:
Annotating Cancer Biology through Non-Invasive Molecular Imaging
-
批准号:10411426
-
项目类别:
-
资助金额:$8.21万
-
财政年份:2019
-
负责人:Jason S. Lewis
-
依托单位:
Annotating Cancer Biology through Non-Invasive Molecular Imaging
-
批准号:10472042
-
项目类别:
-
资助金额:$105.6万
-
财政年份:2019
-
负责人:Jason S. Lewis
-
依托单位:
Annotating Cancer Biology through Non-Invasive Molecular Imaging
-
批准号:9816661
-
项目类别:
-
资助金额:$107.76万
-
财政年份:2019
-
负责人:Jason S. Lewis
-
依托单位:
Pretargeted Clinical Imaging of CA19.9 in Pancreatic Cancer
-
批准号:10441296
-
项目类别:
-
资助金额:$68.84万
-
财政年份:2018
-
负责人:Jason S. Lewis
-
依托单位:
Pretargeted Clinical Imaging of CA19.9 in Pancreatic Cancer
-
批准号:10215431
-
项目类别:
-
资助金额:$68.92万
-
财政年份:2018
-
负责人:Jason S. Lewis
-
依托单位:
Immuno-PET imaging of high-grade neuroendocrine lung tumors using 89Zrrovalpituzumab, a DLL3-targeting monoclonal antibody
-
批准号:10078772
-
项目类别:
-
资助金额:$36.74万
-
财政年份:2017
-
负责人:Jason S. Lewis
-
依托单位:
Immuno-PET imaging of high-grade neuroendocrine lung tumors using 89Zr-rovalpituzumab, a DLL3-targeting monoclonal antibody
-
批准号:9252920
-
项目类别:
-
资助金额:$44.67万
-
财政年份:2017
-
负责人:Jason S. Lewis
-
依托单位:
The Clinical PET Imaging of Metastatic Breast Cancer with Site-Specifically Labeled 89Zr-Trastuzumab
-
批准号:9884743
-
项目类别:
-
资助金额:$68.4万
-
财政年份:2016
-
负责人:Jason S. Lewis
-
依托单位:
Bifunctional ligand development for targeted Positron Emission Tomography (PET) using Zirconium-89
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批准号:9179210
-
项目类别:
-
资助金额:$16.13万
-
财政年份:2016
-
负责人:Jason S. Lewis
-
依托单位:
Radiochemisty
-
批准号:8933547
-
项目类别:
-
资助金额:$35.8万
-
财政年份:2014
-
负责人:Jason S. Lewis
-
依托单位:
PET Imaging of Cancer with pH (Low) Insertion Peptide (pHLIP)
-
批准号:8403829
-
项目类别:
-
资助金额:$45.92万
-
财政年份:2010
-
负责人:Jason S. Lewis
-
依托单位:
PET Imaging of Cancer with pH (Low) Insertion Peptide (pHLIP)
-
批准号:8019129
-
项目类别:
-
资助金额:$47.22万
-
财政年份:2010
-
负责人:Jason S. Lewis
-
依托单位:
PET Imaging of Cancer with pH (Low) Insertion Peptide (pHLIP)
-
批准号:8206765
-
项目类别:
-
资助金额:$54.97万
-
财政年份:2010
-
负责人:Jason S. Lewis
-
依托单位:
PET Imaging of Cancer with pH (Low) Insertion Peptide (pHLIP)
-
批准号:7786528
-
项目类别:
-
资助金额:$48.79万
-
财政年份:2010
-
负责人:Jason S. Lewis
-
依托单位:
DIGITAL IMAGING SYST: CANCER
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批准号:7166439
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项目类别:
-
资助金额:$9.96万
-
财政年份:2005
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负责人:Jason S. Lewis
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依托单位:
DIGITAL IMAGING SYST: PULMONARY MEDICINE, LUNG INJURY
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批准号:7166441
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项目类别:
-
资助金额:$7.47万
-
财政年份:2005
-
负责人:Jason S. Lewis
-
依托单位:
海外基金