The Paired Undergraduate Mentoring Program (PUMP) in Uronephrology

摘要 美国正面临着生物医学劳动力危机，由于进入美国的个人多样性不足， 职业道路，从本科培训STEM专业的自然减员开始。结果，特别是对于 严重影响少数群体和得不到充分服务的人群的疾病，缺乏创新的解决方案， 促进健康成果。慢性肾病和终末期肾病不成比例地影响 非洲裔美国人在美国是一个巨大的医疗和经济负担，年产 管理费用估计为1200亿美元。杜克大学是独特的定位，以解决这一关键 通过建立一个强大的，多样化的和可持续的未来学术生物医学科学家的管道问题。我们 最近成立的医生科学家发展办公室（OPSD）提供了一个可持续的结构， 导师制、专业发展和研究资金。通过利用这一体制结构，我们 能够很好地支持将资源 在整个培训范围内，向本科生介绍各种研究职业机会， 准备高级学员过渡到教师职位，成为强大的独立调查员熟练， 指导来自不同背景的学生。为了解决生物医学劳动力缺口，我们建议 泌尿外科配对本科生导师计划（Uronephrology），将招募不同的队列， 本科生，让他们接触研究技能建设和指导研究经验， 泌尿科和肾脏科。我们将提供循证专业发展活动， 学生参与者和实习生谁将担任日常研究项目的导师。杜克大学 将实现我们的长期目标，解决限制招聘和留住多元化人才的障碍。 通过密集的研究经验，结构化的三角指导， 持续的虚拟参与。该计划的重点是1）实施指导夏季研究 丰富的计划，以发展对尿肾病学研究事业的兴趣，在一个不断上升的多样化的队列 初级和高级本科生; 2）准备下一代尿肾病研究者指导多样化的 通过培训研究生和博士后导师， 他们的关键经验，领导学生的研究项目;和3）准备本科生的多元化队列 研究生培训和进入uronephrology研究事业通过持续参与， 扩展和丰富了夏季研究计划的经验。成功实施拟议的 该计划将导致一个可扩展的模型，为多样化的生物医学研究开发一个强大的管道 跨学科的劳动力。

ABSTRACT The U.S. is facing a biomedical workforce crisis, exacerbated by insufficient diversity among individuals entering the career path, starting with attrition from STEM majors in undergraduate training. The result, particularly for diseases that disparately impact minority and underserved populations, is a lack of innovative solutions to advance health outcomes. Chronic kidney disease and end stage kidney disease disproportionately affect African Americans and represent a substantial medical and economic burden in the U.S., with annual management costs estimated at $120 billion. Duke University is uniquely positioned to address this critical problem by building a robust, diverse, and sustainable pipeline of future academic biomedical scientists. Our recently established Office of Physician Scientist Development (OPSD) offers a sustainable structure for mentorship, professional development, and research funding. By leveraging this institutional structure, we are well positioned to support the development, implementation, and evaluation of a program that links resources across the training spectrum to introduce undergraduate students to varied research career opportunities, while preparing senior trainees transitioning to faculty positions to become strong independent investigators skilled in mentoring students from diverse backgrounds. To address the biomedical workforce gap, we propose the Paired Undergraduate Mentoring Program (PUMP) in Uronephrology, which will recruit diverse cohorts of undergraduate students and expose them to research skills-building and mentored research experiences in urology and nephrology. We will provide evidence-based professional development activities targeting both the student participants and the trainees who will serve as the day-to-day research project mentors. Duke PUMP will achieve our long-term goal, addressing barriers that limit the recruitment and retention of a diverse uronephrology workforce, through intensive research experiences, structured triangular mentorship, and sustained virtual engagement. The program focuses on 1) implementing a mentored summer research enrichment program to develop interest in uronephrology research careers among a diverse cohort of rising junior and senior undergraduates; 2) preparing next-generation uronephrology investigators to mentor a diverse biomedical workforce by training graduate students and postdoctoral associates in mentorship and providing them critical experience leading student research projects; and 3) preparing a diverse cohort of undergraduates for post-graduate training and entry into uronephrology research careers through sustained engagement that extends and enriches the summer research program experience. Successful implementation of the proposed program will lead to a scalable model for development of a robust pipeline for a diverse biomedical research workforce across disciplines.