权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

PROMISE - Program Refinements to Optimize Model Impact and Scalability based on Evidence

PROMISE - 基于证据优化模型影响和可扩展性的程序改进

基本信息

批准号：
10333327
负责人：
Mary Kathryn Irvine
金额：
$ 50.56万
依托单位：
GRADUATE SCHOOL OF PUBLIC HEALTH AND HEALTH POLICY
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-02-15 至 2024-01-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10333327
关键词：
Achievement Acquired Immunodeficiency Syndrome Behavioral Caring Centers for Disease Control and Prevention (U.S.)Cessation of life Cities Client Clinical Collaborations Complex Continuity of Patient Care Cues Data Data Sources Drops Drug usage Effectiveness Enrollment Epidemic Evidence based intervention Evolution Experimental Designs Feedback Funding Funding Agency Future Generations Goals Government HIV Health Health education Health system High Prevalence Incidence Infrastructure Institutes Intervention Investigation Latino Left Low income Medical Mental Health Methods Minority Modeling Morbidity - disease rate New York New York City Outcome Persons Policies Process Program Effectiveness Provider Public Health Randomized Research Research Support Resources Service delivery model Service setting Services Shapes Site Social Work Structure Subgroup Testing Time Training Translating Translations Universities Veterans Viral Viral Load result Vulnerable Populations Work base care coordination care delivery comparison group course implementation design effectiveness study experience experimental study housing instability implementation science improved mortality multiple data sources population health preference prevent programs psychosocial scale up service providers social stigma transmission process treatment as usual

项目摘要

Abstract In New York, the achievement of 90-90-90 goals is jeopardized not by limited access to affordable care and treatment, but by persistent disparities in HIV viral suppression (VS). Complex behavioral and structural barriers to achieving and maintaining VS require coordinated, combination approaches to meet medical and social service needs. In 2009, at 28 Ryan White Part A (RWPA)-funded agencies, the New York City (NYC) Department of Health and Mental Hygiene (DOHMH) launched a multi-component HIV Care Coordination Program (CCP) directed toward the most vulnerable, high-need persons living with HIV (PLWH) in NYC. A systematic CCP effectiveness study began in 2013 (R01 MH101028; PIs: Irvine, Nash). Findings to date suggest that the CCP is superior to usual care for high-need subgroups of PLWH, but there remains substantial room for improvement in short- and long-term VS. In an immediate evidence-to- practice feedback loop, the DOHMH is implementing a refined CCP model in 2018. Greater focusing, tailoring and cues for delivery of key components are expected to increase CCP engagement, reach, fidelity, scalability, effectiveness and impact. The aims of the proposed study are to: 1) Estimate the effectiveness of the revised (vs. original) CCP on timely VS (≤4 months), using experimental methods (Aim 1); 2) Estimate the effectiveness of the revised CCP (vs. `usual care') on longer-term VS, including VS at 12 months and durable viral suppression (DVS) at 24-36 months, using rigorous observational comparison group methods (Aim 2); and 3) Identify attributes and drivers of provider and client engagement in the intervention and provider and client preferences for future revised-CCP delivery and receipt (Aim 3). Prior studies have not demonstrated any intervention to be effective at improving short- and long-term VS among the many PLWH with major barriers to HIV care continuum engagement. The proposed study, to be conducted on a large scale in real-world HIV service settings, will document the rollout and effects of evidence-informed implementation course corrections to an intervention model focused on these most vulnerable PLWH. In this way, the work will advance a second generation of interventions capable of strengthening the care continuum among PLWH who have been unable to achieve desired ART outcomes in existing interventions, due to major structural or psychosocial barriers.

摘要

项目成果

期刊论文数量（8）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Client preferences for HIV Care Coordination Program features in New York City: latent class analysis of a discrete choice experiment.

DOI：
10.1002/jia2.26162
发表时间：
2023-08
期刊：
Journal of the International AIDS Society
影响因子：
6
作者：
通讯作者：

HIV Care Coordination promotes care re-engagement and viral suppression among people who have been out of HIV medical care: an observational effectiveness study using a surveillance-based contemporaneous comparison group.

艾滋病毒护理协调促进了脱离艾滋病毒医疗护理的人的护理重新参与和病毒抑制：使用基于监视的同时比较组的观察有效性研究。

DOI：
10.1186/s12981-021-00398-0
发表时间：
2021-10-12
期刊：
AIDS research and therapy
影响因子：
2.2
作者：
Irvine MK;Robertson MM;Nash D;Kulkarni SG;Braunstein SL;Levin B
通讯作者：
Levin B

Provider preferences for delivery of HIV care coordination services: results from a discrete choice experiment.

DOI：
10.1002/jia2.25887
发表时间：
2022-03
期刊：
Journal of the International AIDS Society
影响因子：
6
作者：
Zimba R;Fong C;Conte M;Baim-Lance A;Robertson M;Carmona J;Gambone G;Nash D;Irvine M
通讯作者：
Irvine M

Mortality among clients in the New York city HIV Care Coordination Program (CCP): incidence and associated clinical factors.