Core C: Biostatistics and Bioinformatics Core

核心 C：生物统计学和生物信息学核心

• 批准号: 10331961
• 负责人: Riyue Bao
• 金额: $ 21.15万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-07-01 至 2027-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10331961
• 关键词: Aftercare; Animals; Applications Grants; Bayesian learning; Bioinformatics; Biological; Biometry; Cancer Center; Clinic; Clinical; Clinical Cancer Center; Clinical Data; Clinical Protocols; Clinical Research; Computer Analysis; Data; Data Analyses; Development; Ensure; Experimental Designs; Genomics; Goals; Head and Neck Cancer; Head and Neck Squamous Cell Carcinoma; Immunohistochemistry; Immunologics; In Vitro; Individual; Laboratories; Malignant Neoplasms; Manuscripts; Methods; Nature; Patients; Preparation; Program Development; Protocols documentation; Quality Control; Reporting; Reproducibility; Research; Research Design; Research Personnel; Research Project Grants; Resource Sharing; Services; Skin Cancer; Specimen; Techniques; Translational Research; Visualization; Work; anticancer research; career development; compare effectiveness; data management; data quality/integrity; data sharing; design; experience; experimental study; in vivo; innovation; member; multidimensional data; stem; translational study

PROJECT SUMMARY – BIOSTATISTICS/BIOINFORMATICS CORE (CORE C) The Biostatistics/Bioinformatics Core (Core C) of the Hillman Cancer Center (HCC) HN SPORE provides services for the design of experiments and the analysis of in vitro, in vivo, clinical, translational and -omics data. The investigators and staff of both segments of the Core have significant experience in research in head and neck cancers, so that data are analyzed in the appropriate scientific context, increasing the Core's efficiency and effectiveness compared to general purpose data analysis services. Biostatistics and Bioinformatics combines classic statistical techniques with contemporary Bayesian, machine learning and genomics methods to ensure that every research project, Developmental Research Program and Career Development Program awardee in the SPORE has access to the most appropriate analyses. The Core will also work closely with Core A (OSD) and Core B to ensure that data flows between laboratories, clinics and analysts are efficient and that data and resource sharing can be effective and comprehensive. This Core C Co-Directors are Dr. Daniel Normolle (Biostatistics) and Dr. Riyue Bao (Bioinformatics) who have assembled an excellent team to help achieve the goals of the HN SPORE.

项目总结-生物统计学/生物信息学核心（核心C） 希尔曼癌症中心（HCC）HN SPORE的生物统计学/生物信息学核心（核心C）提供了 实验设计和体外、体内、临床、转化和组学分析服务 数据核心小组两个部分的研究人员和工作人员在头部研究方面都有丰富的经验。 和颈部癌症，以便在适当的科学背景下分析数据， 与通用数据分析服务相比，效率和有效性。生物统计学和 生物信息学将经典统计技术与当代贝叶斯，机器学习和 基因组学方法，以确保每个研究项目，发展研究计划和职业生涯 SPORE中的发展计划获奖者可以获得最合适的分析。芯会 还与核心A（OSD）和核心B密切合作，以确保实验室、诊所和 分析人员的工作效率高，数据和资源共享可以有效和全面。 该核心C联合主任是丹尼尔诺莫尔博士（生物统计学）和鲍日月博士（生物信息学）， 组建了一支优秀的团队来帮助实现HN SPORE的目标。