Core A: Administrative Core
Core A: Administrative Core
批准号:
10333658
负责人:
John M Sedivy
金额:
$4.14万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2016
资助国家:
美国
项目状态:
未结题
起止时间:
2016-09-01 至 2026-12-31
关键词:
AgeAgingAlzheimer&aposs DiseaseApplications GrantsAttentionBiologyCell LineChronicCollaborationsCommunicationCommunitiesComplementary DNAConsensusDNA DamageData SetDatabasesDementiaDepositionDevelopmentDiseaseEnsureEvaluation ResearchGenomeGoalsHost Defense MechanismInflammagingInflammationInformation DisseminationInnate Immune SystemInsertional MutagenesisInstitutesInstitutionInterferon Type IJointsL1 ElementsLeadLeadershipMediationMentorsModelingMolecularMonitorNerve DegenerationNeuraxisNeurodegenerative DisordersNucleosidesProcessProgress ReportsProtocols documentationPublicationsReagentRecommendationRegulationRepetitive SequenceReporterReportingResearchResearch ActivityResearch PersonnelResearch Project GrantsResolutionResource SharingResourcesRetrotranspositionRetrotransposonReverse Transcriptase InhibitorsRoleServicesSiteSterilityTechnologyTimeTrainingTranscriptUnited States National Institutes of HealthWritingage relatedbaseconflict resolutiondata submissiondesignhigh standardinhibitor therapymeetingsmembermouse modelnew technologynovelprogramspublic databaserecruitresponsetooltranslational potential
中文摘要
项目概要(核心A)
行政核心(核心A)的总体目标是提供科学、方案和财政领导,
船舶,促进参与PPG的不同研究人员之间的沟通渠道,保持协调,
在PPG的总体和长期目标中的作用,并确保PPG产生的资源将受益
科学界。因此,核心A将提供管理、评估和发展这四个方面的机制。
研究项目和两个研究核心的计划。在上述背景下,核心A的任务将
有效协调所有组成部分的活动,如联合选择和设计
使用的模型和资源(细胞系、小鼠模型、转座子报告基因、方案等),发展
新技术和工具,以更有效地促进研究目标,并使科学
社区访问PPG的资源,技术和数据库。以下活动还将
(a)核心A将确保行政和财务方面的工作,
符合NIH和参与机构的要求; 2)核心A将每月组织一次
视频会议和年度面对面务虚会; 3)核心A将负责
4)核心A将促进联合出版物的提交,并与核心A合作,
B,将高通量数据集存入公共数据库; 5)核心A将建立外部咨询
理事会(EAB),并组织项目规划小组的年度审查。
英文摘要
PROJECT SUMMARY (CORE A)
The overall goals of the Administrative Core (Core A) are to provide scientific, programmatic and fiscal leader-
ship, facilitate lines of communication between the different researchers involved in the PPG, maintain cohe-
rence in the PPG’s overall and long-range goals, and ensure that resources resulting from the PPG will benefit
the scientific community. Core A will thus provide the mechanisms to manage, evaluate, and evolve the four
Research Projects and two Research Cores in the program. In the context of the above, the task of Core A will
be the effective coordination of the activities of all the components, such as the selection and design of jointly
used models and resources (cell lines, mouse models, transposon reporters, protocols, etc.), the development
of new technologies and tools to more effectively promote the research goals, and enabling the scientific
community access to the PPG’s resources, technologies, and databases. The following activities will also
contribute to achieving these overall goals: 1) Core A will ensure that the administrative and financial
requirements of the NIH and the participating institutions are met; 2) Core A will organize monthly
videoconferences and annual face-to-face retreats; 3) Core A will be responsible for communications between
the PPG and the NIH; 4) Core A will facilitate the submission of joint publications and, in collaboration with Core
B, the deposition of high-throughput datasets into public databases; 5) Core A will establish the External Advisory
Board (EAB) and organize the annual reviews of the PPG.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Project 1: Activation of Alternative L1 Lifecycles in the CNS with age and Alzheimer's Disease
-
批准号:10581521
-
项目类别:
-
资助金额:$57.05万
-
财政年份:2016
-
负责人:John M Sedivy
-
依托单位:
Role of Retrotransposon Activity in Neurodegeneration and Alzheimer's Disease
-
批准号:10333657
-
项目类别:
-
资助金额:$331.02万
-
财政年份:2016
-
负责人:John M Sedivy
-
依托单位:
Somatic Activation of Retrotransposition: A New Molecular Mechanism of Aging?
-
批准号:9334684
-
项目类别:
-
资助金额:$195.37万
-
财政年份:2016
-
负责人:John M Sedivy
-
依托单位:
Somatic Activation of Retrotransposition: A new Molecular Mechanism of Aging?
-
批准号:9522255
-
项目类别:
-
资助金额:$17.39万
-
财政年份:2016
-
负责人:John M Sedivy
-
依托单位:
Project 1: Activation of Alternative L1 Lifecycles in the CNS with age and Alzheimer's Disease
-
批准号:10333661
-
项目类别:
-
资助金额:$57.97万
-
财政年份:2016
-
负责人:John M Sedivy
-
依托单位:
Somatic Activation of Retrotransposition: A New Molecular Mechanism of Aging?
-
批准号:9755302
-
项目类别:
-
资助金额:$188.86万
-
财政年份:2016
-
负责人:John M Sedivy
-
依托单位:
Role of Retrotransposon Activity in Neurodegeneration and Alzheimer's Disease
-
批准号:10581509
-
项目类别:
-
资助金额:$323.99万
-
财政年份:2016
-
负责人:John M Sedivy
-
依托单位:
Core A: Administrative Core
-
批准号:10581510
-
项目类别:
-
资助金额:$4.16万
-
财政年份:2016
-
负责人:John M Sedivy
-
依托单位:
2015 Aging, Biology of Gordon Research Conference and Gordon Research Seminar
-
批准号:8975254
-
项目类别:
-
资助金额:$5.0万
-
财政年份:2015
-
负责人:John M Sedivy
-
依托单位:
Predoctoral Training in the Molecular Biology of Aging
-
批准号:8459454
-
项目类别:
-
资助金额:$18.06万
-
财政年份:2012
-
负责人:John M Sedivy
-
依托单位:
Predoctoral Training in the Molecular Biology of Aging
-
批准号:8663812
-
项目类别:
-
资助金额:$18.25万
-
财政年份:2012
-
负责人:John M Sedivy
-
依托单位:
Predoctoral Training in the Molecular Biology of Aging
-
批准号:10190750
-
项目类别:
-
资助金额:$19.7万
-
财政年份:2012
-
负责人:John M Sedivy
-
依托单位:
Predoctoral Training in the Molecular Biology of Aging
-
批准号:8847607
-
项目类别:
-
资助金额:$18.44万
-
财政年份:2012
-
负责人:John M Sedivy
-
依托单位:
Predoctoral Training in the Molecular Biology of Aging
-
批准号:8267418
-
项目类别:
-
资助金额:$9.03万
-
财政年份:2012
-
负责人:John M Sedivy
-
依托单位:
Predoctoral Training in the Molecular Biology of Aging
-
批准号:9924417
-
项目类别:
-
资助金额:$19.48万
-
财政年份:2012
-
负责人:John M Sedivy
-
依托单位:
Predoctoral Training in the Molecular Biology of Aging
-
批准号:9279888
-
项目类别:
-
资助金额:$18.84万
-
财政年份:2012
-
负责人:John M Sedivy
-
依托单位:
The Wnt-chromatin axis in aging
-
批准号:8120464
-
项目类别:
-
资助金额:$30.83万
-
财政年份:2009
-
负责人:John M Sedivy
-
依托单位:
Raf Kinase Inhibitory Protein (RKIP): A New Hepatocellular Carcinoma Tumor Suppre
-
批准号:7906068
-
项目类别:
-
资助金额:$21.25万
-
财政年份:2009
-
负责人:John M Sedivy
-
依托单位:
The Wnt-chromatin axis in aging
-
批准号:7939698
-
项目类别:
-
资助金额:$32.08万
-
财政年份:2009
-
负责人:John M Sedivy
-
依托单位:
The Wnt-chromatin axis in aging
-
批准号:7787103
-
项目类别:
-
资助金额:$32.32万
-
财政年份:2009
-
负责人:John M Sedivy
-
依托单位:
海外基金