Short-Term Training Program In Biomedical Sciences

项目摘要/摘要 这项申请是NHLBI T35培训补助金(生物医学短期培训)的竞争性续签 2011年和2016年被授予印第安纳大学医学院(IUSM)。这款T35大 为巩固和扩大IUSM学生研究和奖学金计划做出了贡献 (IMPRS)。IMPR计划的目的是提供一个结构化的研究环境， 医学生对生物医学研究的兴趣，为基础研究和翻译研究创造机会 研究伦理方面的经验和教育。T35的主要目标是作为一个门户来培训和 招募内科医生和科学家。以满足IUSM医学生持续和不断增长的需求 从事生物医学研究和扩大项目多样性的机会，这项申请寻求支持 继续在IMPR计划中每年招收32名积极性高和多样化的学生进行 基础和临床科室心血管、呼吸系统和造血系统疾病的研究 以IUSM为中心。这种水平的支持是合理的，因为学生的持续(实际上是不断增长的)参与是合理的， 学员多样性增加，学生成绩优异。与此同时，我们显著加强了我们的 通过招募史无前例的多样化和由NHLBI资助的研究人员池中的导师来 在过去五年中，提供了一个创新和多样化的培训环境 心肺、血液学和癌症研究。最后，该计划现在正处于一个令人兴奋的转折点， 在第一代T35学员中有几个正在进行研究重量级奖学金或 都在学术教员的职位上工作，将这些校友带回该项目将提供高度的 对于目前的实习生来说，这是宝贵的经验。该T35培训计划是一个中央门户，可以招募和 通过积极参与各种实验室、转化性和临床研究来培训学生 并建立在越来越多的学生参与和越来越多的导师池的基础上。借助更新的T35支持，IMPRS 可以保持和提高医学生对IUSM尖端研究项目的参与度。在……里面 特别是，该计划旨在a)提高学生对从事生物医学的价值的认识 通过鼓励学生在实习期间参与独立项目进行研究；以及b)支持学生 对学术医学的职业感兴趣。这通过1)提供获得以下机会的途径来实现 研究报告和发表，以及2)培养对学位项目的参与，如IUSM 医学博士项目、临床研究和转化教育项目、印第安纳州临床和 翻译科学研究所医学生空档年研究计划，或外部研究 奖学金。该计划的长期目标是增加内科科学家的数量和多样性 在全国范围内，让早年接受医学教育的学生接触以假说为导向的研究 关于疾病的分子和细胞基础以及临床翻译的潜力。

Project Summary/Abstract This application is a competitive renewal of the NHLBI T35 training grant (Short-Term Training in Biomedical Sciences) awarded to Indiana University School of Medicine (IUSM) in 2011 and 2016. This T35 greatly contributed to the consolidation and expansion of the IUSM Student Program for Research and Scholarship (IMPRS). The purpose of the IMPRS program is to provide a structured research environment that engages medical students’ interest in biomedical research, creating opportunities for basic and translational research experience and education in research ethics. The main objective of the T35 is to serve as a portal to train and recruit physician-scientists. To meet the ongoing and increasing demand of IUSM medical students for opportunities to engage in biomedical research and to expand program diversity, this application seeks support to continue to enroll 32 highly motivated and diverse students/year within the IMPRS program to conduct research in cardiovascular, respiratory and hematopoietic disease in basic and clinical departments and centers at IUSM. This level of support is justified by sustained (and actually, growing) student participation, increased trainee diversity, and excellent student outcomes. In parallel, we have significantly strengthened our pool of mentors by recruiting an unprecedented pool of diverse and robustly NHLBI-funded researchers to IUSM over the last five years, thus providing an innovative and diverse training environment in cardiopulmonary, hematological and cancer research. Lastly, the program is now at an exciting inflection point, where several of the first generation of T35 trainees are pursuing research in research-heavy fellowships or are working in academic faculty positions, and bringing these alumni back to the program will provide a highly valuable experience for the current trainees. This T35 training program serves as a central portal to recruit and train students through active engagement in a diverse array of laboratory, translational and clinical research and builds on the growing student participation and increasing mentor pool. With renewed T35 support, IMPRS can maintain and improve medical student engagement in IUSM’s cutting-edge research programs. In particular, the program is designed to a) increase student awareness of the value of engaging in biomedical research by challenging students to take on independent projects during the internship; and b) support students interested in careers in academic medicine. This occurs through 1) providing access to opportunities for research presentation and publication, and 2) fostering engagement with degree programs such as the IUSM MD/PhD program, the Clinical Investigation and Translational Education program, the Indiana Clinical and Translational Sciences Institute medical student gap year for research program, or external research fellowships. The long-term goal of the program is to increase the numbers and diversity of physician scientists nationally by exposing students in their early years of medical education to hypothesis-driven research focused on the molecular and cellular basis of disease and the potential for clinical translation.