Short-Term Training Program In Biomedical Sciences

项目总结/摘要 本申请是NHLBI T35培训补助金（生物医学短期培训）的竞争性更新 科学）授予印第安纳州医学院（IUSM）在2011年和2016年。这款T35 促进了IUSM学生研究和奖学金计划的巩固和扩大 （IMPRS）. IMPRS计划的目的是提供一个结构化的研究环境， 医学生对生物医学研究的兴趣，为基础和转化研究创造机会 在研究道德方面的经验和教育。T35的主要目标是作为一个门户网站， 招募物理学家和科学家为了满足IUSM医学生对以下方面不断增长的需求， 有机会从事生物医学研究和扩大计划的多样性，这一申请寻求支持 继续招收32名高度积极性和多样化的学生/年在IMPRS计划进行 在基础和临床部门开展心血管、呼吸和造血系统疾病的研究， 在IUSM中心。这种程度的支持是合理的持续（实际上，越来越多）的学生参与， 增加学员的多样性和优秀的学生成果。与此同时，我们大大加强了 通过招募前所未有的多样化和强大的NHLBI资助的研究人员， IUSM在过去五年中，从而提供了一个创新和多样化的培训环境， 心肺、血液和癌症研究。最后，该计划现在正处于一个令人兴奋的转折点， 其中第一代T35学员中的几位正在以研究为主的奖学金进行研究，或者 正在学术教师职位工作，并将这些校友带回该计划将提供一个高度 为目前的学员提供了宝贵的经验。这个T35培训计划作为一个中央门户网站， 通过积极参与各种实验室，转化和临床研究来培养学生 并建立在不断增长的学生参与和不断增加的导师库。通过更新的T35支持，IMPRS 可以保持和提高医学生在IUSM的前沿研究项目的参与。在 特别是，该计划旨在a）提高学生对从事生物医学价值的认识 通过挑战学生在实习期间承担独立项目进行研究;以及B）支持学生 对学术医学感兴趣。这是通过1）提供机会， 研究报告和出版物，以及2）促进与学位课程，如IUSM的参与 MD/PhD项目、临床研究和转化教育项目、印第安纳州临床和 转化科学研究所医学生研究项目或外部研究的间隔年 奖学金该计划的长期目标是增加医生科学家的数量和多样性 在全国范围内，通过让学生在医学教育的早期接触假设驱动的研究， 疾病的分子和细胞基础以及临床转化的潜力。

Project Summary/Abstract This application is a competitive renewal of the NHLBI T35 training grant (Short-Term Training in Biomedical Sciences) awarded to Indiana University School of Medicine (IUSM) in 2011 and 2016. This T35 greatly contributed to the consolidation and expansion of the IUSM Student Program for Research and Scholarship (IMPRS). The purpose of the IMPRS program is to provide a structured research environment that engages medical students’ interest in biomedical research, creating opportunities for basic and translational research experience and education in research ethics. The main objective of the T35 is to serve as a portal to train and recruit physician-scientists. To meet the ongoing and increasing demand of IUSM medical students for opportunities to engage in biomedical research and to expand program diversity, this application seeks support to continue to enroll 32 highly motivated and diverse students/year within the IMPRS program to conduct research in cardiovascular, respiratory and hematopoietic disease in basic and clinical departments and centers at IUSM. This level of support is justified by sustained (and actually, growing) student participation, increased trainee diversity, and excellent student outcomes. In parallel, we have significantly strengthened our pool of mentors by recruiting an unprecedented pool of diverse and robustly NHLBI-funded researchers to IUSM over the last five years, thus providing an innovative and diverse training environment in cardiopulmonary, hematological and cancer research. Lastly, the program is now at an exciting inflection point, where several of the first generation of T35 trainees are pursuing research in research-heavy fellowships or are working in academic faculty positions, and bringing these alumni back to the program will provide a highly valuable experience for the current trainees. This T35 training program serves as a central portal to recruit and train students through active engagement in a diverse array of laboratory, translational and clinical research and builds on the growing student participation and increasing mentor pool. With renewed T35 support, IMPRS can maintain and improve medical student engagement in IUSM’s cutting-edge research programs. In particular, the program is designed to a) increase student awareness of the value of engaging in biomedical research by challenging students to take on independent projects during the internship; and b) support students interested in careers in academic medicine. This occurs through 1) providing access to opportunities for research presentation and publication, and 2) fostering engagement with degree programs such as the IUSM MD/PhD program, the Clinical Investigation and Translational Education program, the Indiana Clinical and Translational Sciences Institute medical student gap year for research program, or external research fellowships. The long-term goal of the program is to increase the numbers and diversity of physician scientists nationally by exposing students in their early years of medical education to hypothesis-driven research focused on the molecular and cellular basis of disease and the potential for clinical translation.