VCU Initiative for Maximizing Student Development Program (IMSD)

VCU 最大化学生发展计划 (IMSD)

• 批准号: 10334414
• 负责人: HAMID I AKBARALI
• 金额: $ 48.42万
• 依托单位: VIRGINIA COMMONWEALTH UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-03-15 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10334414
• 关键词: Academic Training; Address; Award; Biomedical Research; Communication; Communities; Community Networks; Complement; Critical Thinking; Degree Completion; Development; Development Plans; Disease; Doctor of Philosophy; Educational Status; Enrollment; Ensure; Environment; Exposure to; Fellowship; Fostering; Funding; Future; Goals; Grant; Healthcare; Individual; Institution; Journals; Measurable; Measures; Medicine; Mentors; Mentorship; NCI Scholars Program; Oral; Outcome; Outcome Measure; Paper; Participant; Peer Review; Personality; Postdoctoral Fellow; Problem Solving; Productivity; Program Development; Publications; Publishing; Research; Research Personnel; Research Training; STEM career; Schools; Science; Students; Study Skills; Testing; Time; Training; Training and Education; Underrepresented Minority; Underrepresented Students; United States National Institutes of Health; Universities; Virginia; Vocational Guidance; Writing; base; biomedical scientist; career; career awareness; demographics; design; doctoral student; experience; graduate student; improved; interest; meetings; novel strategies; peer; posters; pre-doctoral; programs; recruit; skills; student training; success; symposium; undergraduate student; university student

The Virginia Commonwealth University (VCU) IMSD Program has been in effect since 2010 to provide training and increase UR scholars in the biomedical enterprise. The specific goals of the last proposal were (1) To provide mentored research experiences for 16 IMSD Undergraduate Scholars/ year and 4 IMSD PhD students/ year, (2) To use both well-tested and novel strategies to increase academic success of IMSD trainees, (3) To design and deliver enrichment activities that develop trainees' critical thinking/ problem solving skills, improve communications skills, increase awareness of careers that complement their interests and personalities, (4) To ensure that at least 60% of IMSD Undergraduate Scholars enroll in competitive PhD programs in the biomedical sciences, (5) To ensure that ≥90% of IMSD Scholars who enroll complete PhD programs in the biomedical sciences, (6) To use aggressive recruiting strategies to increase URM applications to the Biomedical Sciences Doctoral Portal by 100%, and (7) To increase productivity of URM PhD students to be comparable to that of their peers. Each of these measureable outcomes has been achieved with significant success with 55 undergraduates and 15 PhD scholars supported through the VCU IMSD program. In the past funding cycle, 60% of the UGs have entered PhD programs at various institutions nationally, all PhD scholars have graduated with significant peer-reviewed publications, have remained in the biomedical workforce with 75% entering academic institutions as postdoctoral fellows. We will build upon this promising progress with the following specific aims, 1) Expose 16 UR undergraduates to high quality biomedical research, 2) Elevate 6 highly qualified UR graduate students to a successful PhD, and 3) engage the wider VCU community in biomedical research and professional training. The measureable outcomes of each of these aims are consistent with the goals of the IMSD Program “to develop the pool of a diverse group of highly trained undergraduate and graduate students who go on to research careers and will be available to participate in NIH-funded research.”

弗吉尼亚联邦大学（VCU）IMSD计划自2010年以来一直有效， 并增加生物医学企业的UR学者。最后一项建议的具体目标是：（1） 为16名IMSD本科学者/年和4名IMSD博士生提供指导研究经验/ （2）采用行之有效的新策略，提高IMSD学员的学业成绩，（3） 设计和提供丰富的活动，培养学员的批判性思维/解决问题的技能，提高 沟通技巧，提高对与他们的兴趣和个性互补的职业的认识，（4） 确保至少60%的IMSD本科学者在竞争激烈的博士课程报名参加 生物医学科学，（5）为了确保≥90%的IMSD学者谁注册完成博士课程， 生物医学科学，（6）使用积极的招聘策略来增加URM对 生物医学科学博士门户网站的100%，和（7）为了提高URM博士生的生产力， 与他们的同龄人相比。每一项可衡量的成果都取得了重大进展， 通过VCU IMSD计划，55名本科生和15名博士生获得了成功。过去 资助周期，60%的大学生已经进入全国各机构的博士课程，所有博士学者 毕业时发表了重要的同行评议的出版物，留在生物医学劳动力队伍中， 75%进入学术机构作为博士后研究员。我们将在这一可喜进展的基础上， 以下具体目标，1）暴露16 UR本科生高质量的生物医学研究，2）提升6 高素质的UR研究生到一个成功的博士学位，和3）从事更广泛的VCU社区， 生物医学研究和专业培训。每个目标的可衡量成果如下 与IMSD计划的目标相一致，“开发一个训练有素的多样化群体的人才库， 本科生和研究生谁去研究的职业生涯，并将可参与 国家卫生研究院资助的研究。”

项目成果

Polymorphisms in the receptor for advanced glycation end-products (RAGE) gene and circulating RAGE levels as a susceptibility factor for non-alcoholic steatohepatitis (NASH).

• DOI: 10.1371/journal.pone.0199294
• 发表时间: 2018
• 期刊: PloS one
• 影响因子: 3.7
• 作者: Mehta R;Shaw G;Masschelin P;Felix S;Otgonsuren M;Baranova A;Goodman Z;Younossi Z
• 通讯作者: Younossi Z

Dual inhibition of endocannabinoid catabolic enzymes produces enhanced antiwithdrawal effects in morphine-dependent mice.

内源性大麻素分解代谢酶的双重抑制可增强吗啡依赖小鼠的抗戒断作用。

• DOI: 10.1038/npp.2012.269
• 发表时间: 2013
• 期刊: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
• 作者: Ramesh,Divya;Gamage,ThomasF;Vanuytsel,Tim;Owens,RobertA;Abdullah,RehabA;Niphakis,MicahJ;Shea-Donohue,Terez;Cravatt,BenjaminF;Lichtman,AronH
• 通讯作者: Lichtman,AronH

HIV-1 Tat exacerbates lipopolysaccharide-induced cytokine release via TLR4 signaling in the enteric nervous system.

• DOI: 10.1038/srep31203
• 发表时间: 2016-08-05
• 期刊: Scientific reports
• 影响因子: 4.6
• 作者: Guedia J;Brun P;Bhave S;Fitting S;Kang M;Dewey WL;Hauser KF;Akbarali HI
• 通讯作者: Akbarali HI

Impact of menthol on nicotine intake and preference in mice: Concentration, sex, and age differences.

• DOI: 10.1016/j.neuropharm.2020.108274
• 发表时间: 2020-11-15
• 期刊: Neuropharmacology
• 影响因子: 4.7
• 作者: Bagdas D;Jackson A;Carper M;Chen RY;Akinola LS;Damaj MI
• 通讯作者: Damaj MI

Pharmacological characterization of 5-iodo-A-85380, a β2-selective nicotinic receptor agonist, in mice.

• DOI: 10.1177/02698811221132214
• 发表时间: 2022-11
• 期刊: JOURNAL OF PSYCHOPHARMACOLOGY
• 影响因子: 4.1
• 作者: Akinola, Lois S.;Bagdas, Deniz;Alkhlaif, Yasmin;Jackson, Asti;Gurdap, Cenk O.;Rahimpour, Elnaz;Carroll, F. Ivy;Papke, Roger L.;Damaj, M. Imad
• 通讯作者: Damaj, M. Imad