Technology Core

技术核心

• 批准号: 10333615
• 负责人: mindy katz
• 金额: $ 66.03万
• 依托单位: ALBERT EINSTEIN COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 1982
• 资助国家: 美国
• 起止时间: 1982-09-29 至 2027-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10333615
• 关键词: Aging; Ancillary Study; Biological Markers; Charge; Classification; Clinic; Clinical; Cohort Studies; Collaborations; Communities; Computer software; Consultations; Data; Data Collection; Data Management Resources; Data Provenance; Data Security; Data Set; Data Sources; Data Storage and Retrieval; Dementia; Deposition; Development; Devices; FAIR principles; Failure; Health; International; Maintenance; Measurement; Measures; Memory; Metadata; Methods; Patient Self-Report; Persons; Policies; Procedures; Process; Property; Protocols documentation; Psychometrics; Research; Research Personnel; Running; Secure; Security; Support System; Technology; Testing; Training; United States National Institutes of Health; Validation; arm; clinical biomarkers; cohort; data access; data dictionary; data dissemination; data infrastructure; data integration; data integrity; data management; data pipeline; data repository; data reuse; data sharing; data streams; digital; diverse data; innovation; interoperability; mobile computing; neuropathology; operation; preservation; prevent; programs; psychosocial; quality assurance; repository; response; sensor; statistics; success; theories; wearable device

ABSTRACT The Technology and Data Management (TDM) Core serves two primary functions that are essential for the success of the EAS program project: (1) the management and integration of data, and (2) providing consultative and technical support for data operations. The aims of the TDM Core are as follow: Aim 1. To implement and oversee a central data repository and pipeline to facilitate the seamless exchange, integration and management of data among EAS Cores and Projects. Aim 2. To provide consultative and technical support to facilitate data collection and integration from different data sources (e.g., clinic, self-reports, wearable devices, sensors, biomarkers), and execute an operation plan for running and maintaining the central data infrastructure and management system. Aim 3. To score and evaluate basic psychometric properties (e.g., items and scores distributions, correlations, reliability) of clinical measures, conventional psychosocial scales and ambulatory assessments across Projects in order to provide tidy and analysis-ready datasets for further validation and analyses in the Statistical Core. Aim 4. To support and facilitate data dissemination and consortium collaborations with the scientific community and the public. In line with NIH Policy for data management and sharing (NOT-OD-21-013), and following the governance procedures distributed by the Dissemination Committee, the TDM Core will support the sharing of data, protocols, measurement and testing procedures, and relevant data dictionaries with the broader research community and lay public, by depositing data and metadata using various established repositories and platforms. The TDM Core follows the FAIR principles for scientific data management (Findable, Accessible, Interoperable, and Reusable), and will develop and operate a central data management and technical support system that will meet the scientific aims and research needs of the EAS P01, while also facilitating collaborations and dissemination with the broader research community and public.

摘要 技术和数据管理（TDM）核心提供两个主要功能，这对于 EAS计划项目的成功：（1）数据的管理和集成，以及（2）提供 为数据业务提供咨询和技术支持。TDM核心的目标如下：目标1。到 实施和监督中央数据储存库和管道，以促进无缝交换、整合 EAS核心和项目之间的数据管理。目标2.提供咨询和技术支持 支持促进从不同数据源收集和整合数据（例如，诊所，自我报告， 可穿戴设备、传感器、生物标志物），并执行用于运行和维护中央 数据基础设施和管理系统。目标3.评分和评估基本的心理测量特性 (e.g.,项目和分数分布，相关性，可靠性）的临床措施，传统的心理社会 跨项目的量表和动态评估，以便为 在统计核心中进一步验证和分析。目标4。支持和促进数据传播， 与科学界和公众的联盟合作。符合NIH数据政策 管理和共享（NOT-OD-21-013），并遵循 传播委员会，TDM核心将支持数据，协议，测量和测试的共享 程序和相关数据字典与更广泛的研究界和公众，通过存放 使用各种已建立的储存库和平台收集数据和元数据。TDM核心遵循FAIR 科学数据管理原则（可查找、可解释、可互操作和可重用），并将制定 并运行一个中央数据管理和技术支持系统，以满足科学目标， EAS P01的研究需求，同时也促进了与更广泛的合作和传播 研究社区和公众。