Neuroimaging and Neuromodulation Core

神经影像和神经调节核心

• 批准号: 10338139
• 负责人: LINDA L CARPENTER
• 金额: $ 25.79万
• 依托单位: BUTLER HOSPITAL (PROVIDENCE, RI)
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-03-01 至 2024-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10338139
• 关键词: Address; Behavior; Brain; Businesses; Centers of Research Excellence; Clinical; Cognitive; Collection; Communities; Complex; Consultations; Custom; Data; Data Collection; Diffusion Magnetic Resonance Imaging; Educational workshop; Electric Stimulation; Ensure; Equipment; Fees; Functional Magnetic Resonance Imaging; Funding; Future; Goals; Grant; High Performance Computing; Hospitals; Hour; Infrastructure; Joints; Laboratories; Magnetic Resonance Imaging; Magnetism; Medical; Mental disorders; Methods; Mission; Modality; Modeling; National Institute of General Medical Sciences; Nature; Neuronavigation; Participant; Pathology; Patients; Phase; Physiologic pulse; Population; Protocols documentation; Research; Research Design; Research Infrastructure; Research Personnel; Research Project Grants; Research Project Summaries; Resources; Rest; Rhode Island; Role; Sampling; Scientist; Series; Services; Supervision; Technical Expertise; Techniques; Testing; Time; Training; Training Support; Training and Infrastructure; Transcranial magnetic stimulation; Universities; Work; base; clinically relevant; computing resources; data acquisition; data integration; data management; data resource; design; electric field; medical specialties; meetings; model development; neuroimaging; neuropsychiatric disorder; neuropsychiatry; neuroregulation; programs; repetitive transcranial magnetic stimulation; research facility; skills; training opportunity

Project Summary The research projects proposed in the COBRE Center for Neuromodulation involve a broad range of neuroimaging and neuromodulatory methods, and often involving clinical participants or those with neuropsychiatric pathology. Neuroimaging methods include task- and resting state MRI, and stimulation methods include single pulse and repetitive transcranial magnetic stimulation or transcranial direct stimulation. These techniques are, by their nature, highly complex and require significant technical mastery to successful deploy them in clinical populations. This problem is significantly prominent for relatively junior investigators or those new to these fields. The function of this COBRE Neuroimaging and Neuromodulation Core (NNC) is to provide ongoing expert support, training, assistance and advice to the COBRE project leaders in the wide-range of practical aspects of implementation, data collection, and management related to these methods. Therefore, the Specific Aims of the NNC are to (1) provide support, training and assistance to COBRE Project Leaders (PLs) to promote and facilitate the acquisition of high quality neuroimaging data; (2) provide support, training and assistance to COBRE PLs to facilitate the application of high quality neuromodulation; and (3) to establish core resources with a trajectory toward self- sustaining and enduring status that will serve the larger neuromodulation research community in Rhode Island. To meet these aims, the NNC of this COBRE Center will provide highly specialized expertise, hands-on training, educational forums, and assistance in numerous aspects of protocol implementation, data acquisition and resources as required to meet the aims in each COBRE project and the unique needs of neuromodulation investigators. It will offer critical laboratory space, equipment, infrastructure, and medical supervision needed by investigators working with clinical samples. By meeting these goals, the NNC will (a) accelerate the pace of high-quality mechanism-oriented COBRE research; (b) facilitate the use of safe and scientifically rigorous stimulation protocols; (3) ensure the availability and accessibility of high quality research infrastructure over time for COBRE investigators and the broader Rhode Island research community.

项目摘要 在毛绒神经调节中心提出的研究项目涉及广泛 神经影像学和神经调节方法的范围，并且通常涉及临床参与者 或患有神经精神病学的患者。神经影像学方法包括任务和休息状态 MRI和刺激方法包括单脉冲和重复的经颅磁 刺激或经颅直接刺激。从本质上讲，这些技术是高度的 复杂的，需要大量的技术掌握才能成功将它们分配到临床上 人群。对于相对较小的研究人员或那些人来说，这个问题非常重要 这些领域的新手。这种毛毛神经影像和神经调节核心的功能 （NNC）是为柯布尔提供持续的专家支持，培训，帮助和建议 实施，数据收集和 与这些方法相关的管理。因此，NNC的具体目的是（1） 向山羊项目负责人（PLS）提供支持，培训和援助，以促进和 促进获得高质量的神经影像数据； （2）提供支持，培训 并提供帮助，以促进高质量的应用 神经调节； （3）建立具有自我轨迹的核心资源 维持和持久的状态，将为更大的神经调节研究服务 罗德岛的社区。为了满足这些目标，该毛病中心的NNC将提供 高度专业化的专业知识，动手培训，教育论坛和众多协助 协议实施，数据获取和资源的各个方面以实现目标 在每个毛茸茸的项目和神经调节研究者的独特需求中。它将提供 重要的实验室空间，设备，基础设施和医疗监督 研究人员使用临床样品。通过实现这些目标，NNC将（a）加速 高质量机制的鞋垫研究的速度； （b）促进安全和 科学严格的刺激方案； （3）确保高可用性和可访问性 山科研究人员和更广泛的罗德岛的质量研究基础设施随着时间的推移 研究社区。