Native American Short-Term Research Education Program in Children's Health

项目概要/摘要 AI/AN社区的健康差异存在于整个生命周期中，包括发病率和死亡率， 心血管疾病、吸烟相关疾病、肥胖、糖尿病、感染、慢性肝病/肝硬化， 药物滥用和精神创伤等等AI/AN患者的死亡年龄更小，25%的AI/AN死亡 在45岁之前发生，而非洲裔美国人为15%，白人为7%。消除健康 差距，需要识别，招聘，教育和培训最有才华的科学家， 美国我们的整体和全面的美洲原住民夏季研究实习计划， 心血管、肺和血液疾病（NARI-NHLBI）是根据以下原则开发的： 社区参与，以支持AI/AN学生（谁是代表性不足，服务不足，在这两个较高的 教育和医疗保健），最终目标是提高AI/AN在 科学/医学，从而缩小AI/AN健康差异的差距。在上一次更新中，我们 扩大到包括NARI-MD/PhD计划。NARI-NHLBI和MD/PhD本科生参与者 接受研究，文化和专业的指导和培训与承诺的社区成员， 知名科学家在NARI-NHLBI倡议的帮助下，NARI-MD/PhD现在是一个可持续的 NARI计划的合作伙伴。迄今为止，NARI-NHLBI的65名参与者代表35个部落国家， 学院/大学，20个家乡州和10名NARI-MD/PhD参与者代表5个部落国家，9 学院/大学和6个州。在65名NARI-NHLBI计划参与者中，有56名（86%） 完成了学士学位，其余9人（14%）是目前的本科生。的10 NARI-MD/PhD项目参与者中，7人（70%）完成了学士学位，其余3人（30%） 现在的本科生。没有人从大学退学。迄今为止，有17名（26%）NARI-NHLBI 参与者和6名（60%）NARI-MD/PhD参与者曾在生物医学科学领域从事研究 助手在获得本科学位后，56名NARI-NHLBI毕业生中有28名（50%）， (29在7名NARI-医学博士/博士毕业生中，有16%的人继续在健康/科学领域接受教育： NHLBI和1名NARI-MD/PhD参与者被接受进入研究生课程; 12名NARI-NHLBI和1名NARI- MD/PhD参与者被医学院录取。我们目前的NARI参与者继续报告说， 心血管疾病，肥胖和吸烟相关疾病是他们家庭的首要健康问题。 因此，我们希望继续为NARI学员在以下领域提供NARI-NHLBI研究经验： 心血管、肺和血液学研究。正是有了这个建议，我们希望继续我们的 为12名对NARI-NHLBI研究感兴趣的AI/AN参与者提供了成功的夏季研究支持， 扩大我们的专业发展机会，以更好地参与NARI-NHLBI参与者的基本 实验室和临床技能。

PROJECT SUMMARY/ABSTRACT Health disparities in AI/AN communities exist throughout the lifespan and include morbidity and deaths from cardiovascular disease, smoking related illnesses, obesity, diabetes, infection, chronic liver disease/cirrhosis, substance abuse, and trauma, among others. AI/AN people die at a younger age with 25% of AI/AN deaths occurring before age 45, compared with 15% of African Americans and 7% of Whites. Eliminating health disparities, requires the identification, recruitment, education, and training of the most talented scientists in the U.S. Our holistic and comprehensive Native American Summer Research Internship program in Cardiovascular, Pulmonary, and Hematology diseases (NARI-NHLBI) was developed, based on principles of community engagement, to support AI/AN students (who are underrepresented and underserved in both higher education and healthcare) with an ultimate goal of increasing AI/AN representation and leadership in science/medicine and thus narrow the gap of significant AI/AN health disparities. During the last renewal, we expanded to include the NARI-MD/PhD Program. NARI-NHLBI and MD/PhD undergraduate participants receive research, cultural, and professional mentorship and training with committed community members and renowned scientists. With the help of this NARI-NHLBI initiative, the NARI-MD/PhD is now a sustainable partner within the NARI program. To date, 65 NARI-NHLBI participants represent 35 tribal nations, 35 colleges/universities, and 20 home states and 10 NARI-MD/PhD participants represent 5 tribal nations, 9 colleges/universities, and 6 home states. Of the 65 NARI-NHLBI Program participants, 56 (86%) have completed a bachelor’s degree and the remaining 9 (14%) are current undergraduate students. Of the 10 NARI-MD/PhD Program participants, 7 (70%) have completed a BS degree and the remaining 3 (30%) are current undergraduate students. No one has dropped out of college. To date, 17 (26%) NARI-NHLBI participants and 6 (60%) NARI-MD/PhD participants have worked in biomedical science fields as research assistants. Upon obtaining their undergraduate degree, 28 (50%) of the 56 NARI-NHLBI graduates and 2 (29%) of the 7 NARI-MD/PhD graduates are continuing their education in the health/science fields: 16 NARI- NHLBI and 1 NARI-MD/PhD participants were accepted into a graduate program; 12 NARI-NHLBI and 1 NARI- MD/PhD participants were accepted into medical school. Our current NARI participants continue to report that cardiovascular disease, obesity, and smoking related illness were the top health concerns of their families. Thus, we hope to continue the current NARI-NHLBI research experiences for NARI trainees in the field of cardiovascular, pulmonary and hematology research. It is with this proposal, that we hope to continue our successful summer research support for twelve AI/AN participants interested in NARI-NHLBI research and expand our professional development opportunities to better engage NARI-NHLBI participants in basic laboratory and clinical skills.