Core D: Research Experience and Training Coordination Core

核心 D：研究经验和培训协调核心

• 批准号: 10351939
• 负责人: JOHN M ESSIGMANN
• 金额: $ 6.35万
• 依托单位: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-01 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10351939
• 关键词: Animal Model; Award; Awareness; Biomedical Research; Carcinogens; Chemicals; Chloramines; Communities; Data; Data Analyses; Dependence; Development; Devices; Educational workshop; Engineering; Ensure; Environmental Engineering technology; Environmental Health; Environmental Science; Ethics; Evaluation; Exposure to; Family; Fellowship; Filtration; Fostering; Foundations; Gender; Goals; Hazardous Chemicals; Health; Human; Influentials; Interdisciplinary Study; Laboratories; Lead; Learning; Mainstreaming; Measures; Mentors; Mentorship; Methods; Mission; Municipalities; Mutagens; N-nitrosodimethylamine; Nitrosamines; Nitroso Compounds; Personal Satisfaction; Persons; Policies; Postdoctoral Fellow; Problem Solving; Public Health; Race; Research; Research Personnel; Research Project Grants; Research Support; Research Training; Risk; Rotation; STEM career; Science; Social Responsibility; Students; Superfund; System; Time; Training; Translational Research; Translations; Tribes; Water; Work; career; career development; community engagement; data management; diversity and inclusion; drinking water; experience; graduate student; implicit bias; innovation; meetings; member; next generation; programs; recruit; responsible research conduct; sensor; superfund chemical; superfund site; supportive environment; training opportunity; undergraduate research experience; underrepresented minority student; water treatment

PROJECT SUMMARY/ABSTRACT – RESEARCH EXPERIENCE AND TRAINING COORDINATION CORE N-Nitrosamines are a family of chemicals that include some of the most potent mutagens known. N-Nitrosamines are a major concern for people who live near the Olin Chemical Superfund Site, and they are also a concern of the Passamaquoddy Tribe, because the water treatment methods used for their drinking water are known to lead to formation of N-nitrosamines. The mission of the Research Experience and Training Coordination Core (RETCC) is to recruit, train, and engage the best and the brightest students for careers in Biomedical Research (BMR) and Environmental Science and Engineering (ESE) with a focus on public health. With support from the RETCC, trainees will participate in all of the proposed research, engagement, and translation activities, and they will contribute data to and benefit from the Data Management and Analysis Core (DMAC). As such, trainees fuel the entire MIT SRP program. By fostering and enabling interactions among trainees and between trainees and leaders, the RETCC supports an innovative Systems Approach of inter-dependencies among subsystems (Projects and Cores). Via a Systems Approach, all trainees impact and are impacted by all of the Projects and Cores via a network of connections that are fostered by the Administrative Core and the DMAC. Data generated by trainees will be managed by the Data Management and Analysis Core and will be integrated with data from other parts of the program to contribute to risk evaluation. Innovative aspects of the RETCC include cross- disciplinary research opportunities, training in how research can be leveraged to impact policy, and a new “MIT SRP Exploration Program” that enables trainees to spend time in other MIT laboratories. In addition, there will be several approaches to support pipeline development so as to increase the number of top students with diverse backgrounds and expertise pursuing careers in environmental health sciences and engineering. This work will include creating an MIT undergraduate research opportunity that focuses on SRP research, a new “Public Health Democratization” Pipeline Project to connect URM SRP Trainees with younger URM students. Specific Aim 1 is to provide opportunities to trainees for research, translation, community engagement, and data analysis that will help protect human health from hazardous chemicals. Specific Aim 2 is to strengthen and create programs to promote professional development. Specific Aim 3 is to recruit and promote diverse students and postdocs. Specific Aim 4 is to provide formal training to ensure that MIT SRP trainees have successful and responsible careers in biomedical research and environmental science and engineering. The Administrative Core will foster opportunities for trainees to participate in research translation, which includes interactions with stakeholders. Furthermore, the Community Engagement Core (CEC) will open doors for trainees to work with community members, including helping to deploy sensors and a filtration device that will destroy N-nitrosamines. Taken together, the RETCC provides the foundation upon which trainees thrive and enables the collective impact of the entire program.

项目摘要/摘要--研究经验和培训协调核心 N-亚硝胺是一类化学物质，其中包括一些已知的最强的诱变剂。N-亚硝胺 是居住在奥林化学超级基金网站附近的人的主要担忧，他们也是 PassamAquoddy部落，因为他们饮用水所用的水处理方法已知会导致 形成N-亚硝胺。研究体验与培训协调核心的使命 (RETCC)是招募、培训和聘用最优秀和最聪明的学生从事生物医学研究 (BMR)和环境科学与工程(ESE)，重点是公共卫生。得到了来自 RETCC，实习生将参与所有拟议的研究、参与和翻译活动，他们 将向数据管理和分析核心(DMAC)贡献数据并从中受益。因此，实习生的燃料 整个麻省理工学院SRP项目。通过促进受训人员之间以及受训人员与 作为领导者，RETCC支持子系统之间相互依赖的创新系统方法 (项目和核心)。通过系统方法，所有受训人员影响所有项目并受其影响 通过由管理核心和DMAC培育的连接网络的核心。生成的数据 学员将由数据管理和分析核心管理，并将与来自 该计划的其他部分为风险评估做出贡献。RETCC的创新方面包括交叉- 学科研究机会，如何利用研究影响政策的培训，以及一个新的“麻省理工学院” SRP探索计划“，使学员能够花时间在其他麻省理工学院的实验室。此外，还将有 是支持渠道发展的几种方法，以增加具有多样化的优等生的数量 从事环境健康科学和工程领域工作的背景和专业知识。这项工作将 包括创建专注于SRP研究麻省理工学院本科生研究机会，这是一种新的“公共卫生” 民主化“渠道项目，连接市建局SRP学员和较年轻的市建局学员。具体目标1 是为学员提供研究、翻译、社区参与和数据方面的机会 将有助于保护人类健康免受危险化学品伤害的分析。具体目标2是加强 并创建促进职业发展的计划。具体目标3是招聘和提拔 不同的学生和博士后。具体目标4是提供正式培训，以确保麻省理工学院SRP 学员在生物医学研究和环境科学领域拥有成功和负责任的职业生涯。 和工程学。行政核心将为学员提供参与研究的机会 翻译，包括与利益相关者的互动。此外，社区参与核心(CEC) 将为学员打开与社区成员合作的大门，包括帮助部署传感器和过滤 可以摧毁N-亚硝胺的装置。综上所述，RETCC为学员提供了 茁壮成长，并使整个计划产生集体影响。