Use of advanced analytics to understand brain-behavior screen media activity relationships in ABCD data
Use of advanced analytics to understand brain-behavior screen media activity relationships in ABCD data
批准号:
10358692
负责人:
Marc N Potenza
金额:
$130.4万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2021
资助国家:
美国
项目状态:
已结题
起止时间:
2021-09-10 至 2024-09-09
关键词:
Addictive BehaviorAddressAdolescenceAdolescentAdolescent and Young AdultAgeBehaviorBehavioralBig DataBiologicalBrainBrain StemBrain regionCellular PhoneChildChildhoodComplexCouplingCross-Sectional StudiesDataDevelopmentDiffusion Magnetic Resonance ImagingDiseaseExhibitsExposure toGenderGenerationsGuide preventionGuidelinesHealthHourIndividualInternetInvestigationJointsLinkMapsMeasuresMediatingMediationMental HealthMethodsModelingPatternPrefrontal CortexProcessResearchRestRisk BehaviorsRoleSamplingSiteSleepSleep disturbancesSocial NetworkStructureSurveysTechnologyThalamic structureTimeUnited States National Institutes of HealthYouthadvanced analyticsagedanalytical methodbaseboysbrain behaviorbrain morphologyclinical careclinically relevantcognitive developmentconnectomedigitalearly adolescenceexternalizing behaviorfollow-upgender differencegirlsgray matterindexingindividual variationinnovationinsightlongitudinal analysisneuroimagingnovelpredictive modelingrecruitrelating to nervous systemsexsocial mediatime usetv watchingwhite matter
中文摘要
项目总结/文摘
英文摘要
Project Summary/Abstract
Growing up in a media-saturated world, the current generation of children and adolescents spend on average 6-
9 hours each day on screen media activities (SMAs). Therefore, SMA is a topic of considerable concern in the
USA and elsewhere. Given changes in digital technologies and their usage over the past several decades, there
is a significant gap in our understanding of shorter- and longer-term impacts of SMA on brain-behavior
relationships. Prior studies suggest that problematic patterns of internet use (e.g., internet gaming disorder
(IGD)) are linked to brain structural and functional alterations. However, the majority of research focuses on
identifying individual SMA-related brain regions, which provide a crude approximation or an incomplete view of
factors underlying these complex behaviors. We believe that consideration of brain networks is crucial to
understanding neurodevelopmental mechanisms of SMA and associated behaviors. In this application, we
propose to use data from the longitudinal Adolescent Brain Cognitive Development (ABCD) study to investigate
network-level neural substrates linked to SMA, sleep disturbances and other clinically relevant measures.
Multiple advanced analytical approaches will be used to extract novel features at both structural and functional
levels. For example, the Joint and Individual Variance Explained (JIVE) method will be used to extract biologically
meaningful cortical-subcortical covariation patterns. In this project, we aim to (1) establish relationships between
SMA and brain structural and functional development in children aged 9-10 years; and, (2) investigate a potential
mediating role of sleep disturbances on the relationship between SMA and brain structural and functional
development. Our study uses innovative analytical methods to understand complex SMA-brain-behavior
relationships in a large, developing sample recruited at 21 sites across the United Sates. Results from this
application should provide important insights into understanding the neural processes involved in SMA, sleep
disturbances and other clinically relevant behaviors within a developmental context.
期刊论文(4)
专著(0)
科研奖励(0)
会议论文
DOI:
10.3390/nu15040827
发表时间:
2023-02-06
期刊:
Nutrients
影响因子:
5.9
作者:
[Mestre-Bach G, Potenza MN]
通讯作者:
Potenza MN
DOI:
10.1007/s40429-022-00462-3
发表时间:
2023
期刊:
CURRENT ADDICTION REPORTS
影响因子:
4.3
作者:
[Mestre-Bach, Gemma, Potenza, Marc N]
通讯作者:
Potenza, Marc N
Problematic use of the Internet in low- and middle-income countries before and during the COVID-19 pandemic: a scoping review.
在COVID-19-19大流行之前和期间,在低收入和中等收入国家中使用互联网的问题:范围审查。
DOI:
10.1016/j.cobeha.2022.101208
发表时间:
2022-12
期刊:
CURRENT OPINION IN BEHAVIORAL SCIENCES
影响因子:
5
作者:
[Gjoneska, Biljana, Potenza, Marc N., Jones, Julia, Sales, Celia M. D., Hranov, Georgi, Demetrovics, Zsolt]
通讯作者:
Demetrovics, Zsolt
Cortical subcortical reorganization and risk behaviors of early alcohol use initiation
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批准号:10665741
-
项目类别:
-
资助金额:$34.44万
-
财政年份:2021
-
负责人:Marc N Potenza
-
依托单位:
Cortical subcortical reorganization and risk behaviors of early alcohol use initiation
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批准号:10317213
-
项目类别:
-
资助金额:$35.88万
-
财政年份:2021
-
负责人:Marc N Potenza
-
依托单位:
Vitamin D Modulation of Midbrain Dopamine Function: A 11C-PHNO PET Study in Healthy Humans
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批准号:10022445
-
项目类别:
-
资助金额:$82.82万
-
财政年份:2019
-
负责人:Marc N Potenza
-
依托单位:
Nitric Oxide Facilitates Nicotine Absorption During Cigarette Smoking
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批准号:9342752
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项目类别:
-
资助金额:$20.94万
-
财政年份:2016
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负责人:Marc N Potenza
-
依托单位:
Functional networks related to cocaine dependence and its treatment and relapse
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批准号:9262879
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项目类别:
-
资助金额:$25.13万
-
财政年份:2016
-
负责人:Marc N Potenza
-
依托单位:
Translational Research of Cocaine, Striatum, and Impulsivities
-
批准号:7779707
-
项目类别:
-
资助金额:$95.94万
-
财政年份:2010
-
负责人:Marc N Potenza
-
依托单位:
Translational Research of Cocaine, Striatum, and Impulsivities
-
批准号:8507681
-
项目类别:
-
资助金额:$84.95万
-
财政年份:2010
-
负责人:Marc N Potenza
-
依托单位:
Scientific and Administrative Core
-
批准号:7797220
-
项目类别:
-
资助金额:$17.59万
-
财政年份:2010
-
负责人:Marc N Potenza
-
依托单位:
Translational Research of Cocaine, Striatum, and Impulsivities
-
批准号:8113976
-
项目类别:
-
资助金额:$92.95万
-
财政年份:2010
-
负责人:Marc N Potenza
-
依托单位:
Translational Research of Cocaine, Striatum, and Impulsivities
-
批准号:8307523
-
项目类别:
-
资助金额:$90.21万
-
财政年份:2010
-
负责人:Marc N Potenza
-
依托单位:
fMRI of choice and Response Impulsivity in CD
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批准号:7797225
-
项目类别:
-
资助金额:$11.44万
-
财政年份:2010
-
负责人:Marc N Potenza
-
依托单位:
International Society for Research on Impulsivity Scientific Meeting
-
批准号:7675147
-
项目类别:
-
资助金额:$3.96万
-
财政年份:2009
-
负责人:Marc N Potenza
-
依托单位:
fMRI of Stress & Self-Control in Smoking & Obesity (7 of 14)
-
批准号:8100531
-
项目类别:
-
资助金额:$23.54万
-
财政年份:2007
-
负责人:Marc N Potenza
-
依托单位:
fMRI of Stress & Self-Control in Smoking & Obesity (7 of 14)
-
批准号:7658999
-
项目类别:
-
资助金额:$8.27万
-
财政年份:2007
-
负责人:Marc N Potenza
-
依托单位:
fMRI of Stress & Self-Control in Smoking & Obesity (7 of 14)
-
批准号:7502647
-
项目类别:
-
资助金额:$24.84万
-
财政年份:2007
-
负责人:Marc N Potenza
-
依托单位:
fMRI of Stress & Self-Control in Smoking & Obesity (7 of 14)
-
批准号:7869230
-
项目类别:
-
资助金额:$23.75万
-
财政年份:2007
-
负责人:Marc N Potenza
-
依托单位:
fMRI of Stress & Self-Control in Smoking & Obesity (7 of 14)
-
批准号:7466478
-
项目类别:
-
资助金额:$25.2万
-
财政年份:2007
-
负责人:Marc N Potenza
-
依托单位:
fMRI of Stress & Self-Control in Smoking & Obesity (7 of 14)
-
批准号:7657425
-
项目类别:
-
资助金额:$24.8万
-
财政年份:2007
-
负责人:Marc N Potenza
-
依托单位:
fMRI of Craving in Addictions: Gender Differences
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批准号:6985483
-
项目类别:
-
资助金额:$32.01万
-
财政年份:2005
-
负责人:Marc N Potenza
-
依托单位:
fMRI of Craving in Addictions: Gender Differences
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批准号:7675006
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项目类别:
-
资助金额:$3.25万
-
财政年份:2005
-
负责人:Marc N Potenza
-
依托单位:
海外基金