Affective Executive Functioning as a Mechanism of Mindfulness-Based Cognitive Therapy: A Pilot Randomized Controlled Trial
情感执行功能作为基于正念的认知治疗的机制:一项随机对照试验
基本信息
- 批准号:10370848
- 负责人:
- 金额:$ 17.33万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2022
- 资助国家:美国
- 起止时间:2022-01-01 至 2026-12-31
- 项目状态:未结题
- 来源:
- 关键词:AddressAdherenceAdultAffectAffectiveAttentionBackBehaviorClinical TrialsCodeCognitionCognitiveCommunitiesComputersConsciousData AnalysesDepressed moodDiseaseEducational workshopEmotionalEnvironmentExecutive DysfunctionFinancial HardshipGeneral PopulationGoalsGrantHealthHealth educationHomeHospitalsImpairmentIndividualInstitutionInterventionKnowledgeLiteratureMajor Depressive DisorderMeasuresMental DepressionMental HealthMentorsMethodsMind-Body InterventionMindfulness TrainingModelingMonitorMood DisordersNational Center for Complementary and Integrative HealthNeurocognitiveOutcomeParticipantPatientsPersonal SatisfactionProcessRandomizedRandomized Controlled TrialsReadingRelapseResearchResearch EthicsResearch MethodologyResearch PersonnelRiskScheduleServicesSeveritiesStimulusStructureSystemTestingTimeTrainingTraining SupportTreatment ProtocolsUniversitiesUpdateWorkarmattentional biasbasecognitive functiondaily functioningdepressive symptomsefficacious treatmentemotional stimulusexecutive functionexperienceimprovedinformation processinginnovationmeetingsmental setmindfulnessmindfulness based cognitive therapymindfulness interventionnoveloperationpreventprogramspsychoeducationalrecruitreduce symptomsresearch and developmentresilienceskillssymposiumtheoriestraining opportunity
项目摘要
PROJECT SUMMARY/ABSTRACT
Mindfulness-Based Cognitive Therapy (MBCT) is an efficacious treatment for patients with symptoms of depression. However, the processes by which MBCT achieves its outcomes are not well understood. Drawing on literature on basic cognitive functioning and cognitive biases in depression, this K23 will use a randomized controlled trial to test the effect of MBCT vs. Health Education (HE) on affective inhibition (an important component of executive functioning (EF)), and a possible mechanism of action by which MBCT has an impact on depression symptoms. As a secondary aim, this project will also test the effect of MBCT vs. HE on affective updating and affective shifting (two remaining components of EF). In exploratory analyses, we will examine whether depression symptom severity covaries with change in affective EF (i.e., affective inhibition, shifting, and updating) overtime, and whether adherence to the treatment protocol predicts endpoint EF. To accomplish these goals, 76 adult participants with elevated depression symptoms will be recruited from the community and will be randomized to either an 8-week MBCT course at the Mindfulness Center at Brown University or an 8-week Psychoeducational Health Education Class (i.e., a control arm). Participants will complete validated computer-based tasks of affective EF at 5-assessments, 2 before, 2 during, and 1 after, the 8-week MBCT or HE programs. This project directly addresses NCCIH’s objective to advance the understanding of mechanisms through which mind and body approaches affect health, resilience and well-being. This project will directly address the candidate’s training goals of gaining clinical trials methods experience with mood disorders, expanding knowledge of mindfulness-based interventions (specifically MBCT), gain knowledge in neurocognitive assessment of individuals with depression symptoms, receive training in repeated longitudinal assessment, and further develop professional development, research ethics, and grants management skills. The candidate will complete a number of formal and informal activities (e.g., courses, workshops, conferences, directed readings, and regularly scheduled meetings with mentors) to meet the training goals. These training goals will assist the candidate to become a successful independent investigator examining cognitive mechanisms of mind-body interventions for depression and related disorders. The Mindfulness Center at Brown University and Butler Hospital are the ideal environments for this project, as they are leading institutions in clinical trials research and mindfulness-based interventions, with numerous opportunities for training and support services embedded within the systems.
项目总结/文摘
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Morganne A Kraines其他文献
Personality Disorder Traits as a Moderator of Poor Social Problem-Solving Skills and Depressive Symptoms
人格障碍特征是解决社会问题的能力差和抑郁症状的调节因素
- DOI:
10.1027/1614-0001/a000132 - 发表时间:
2014 - 期刊:
- 影响因子:1.4
- 作者:
E. Sheets;Morganne A Kraines - 通讯作者:
Morganne A Kraines
Implicit bias for suicide persists after ideation resolves
意念消除后,对自杀的隐性偏见仍然存在
- DOI:
10.1016/j.psychres.2020.112784 - 发表时间:
2020 - 期刊:
- 影响因子:11.3
- 作者:
T. Wells;Raymond P. Tucker;Morganne A Kraines;Logan M. Smith;Emma L. Unruh - 通讯作者:
Emma L. Unruh
Acceptability, feasibility, and preliminary efficacy of a prenatal walking program for depressed pregnant women
抑郁孕妇产前步行计划的可接受性、可行性和初步效果
- DOI:
- 发表时间:
2023 - 期刊:
- 影响因子:0
- 作者:
C. Battle;C. Schofield;Morganne A Kraines;Ana M. Abrantes - 通讯作者:
Ana M. Abrantes
Extending a Rejection Sensitivity Model to Suicidal Thoughts and Behaviors in Sexual Minority Groups and to Transgender Mental Health
将拒绝敏感性模型扩展到性少数群体的自杀想法和行为以及跨性别者的心理健康
- DOI:
10.1007/s10508-019-01596-8 - 发表时间:
2019 - 期刊:
- 影响因子:3.8
- 作者:
T. Wells;Raymond P. Tucker;Morganne A Kraines - 通讯作者:
Morganne A Kraines
Trait mindfulness and attention to emotional information: An eye tracking study
特质正念和对情绪信息的关注:一项眼球追踪研究
- DOI:
- 发表时间:
2021 - 期刊:
- 影响因子:2.4
- 作者:
Morganne A Kraines;L. J. Kelberer;C. K. Marks;T. Wells - 通讯作者:
T. Wells
Morganne A Kraines的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Morganne A Kraines', 18)}}的其他基金
Affective Executive Functioning as a Mechanism of Mindfulness-Based Cognitive Therapy: A Pilot Randomized Controlled Trial
情感执行功能作为基于正念的认知治疗的机制:一项随机对照试验
- 批准号:
10544174 - 财政年份:2022
- 资助金额:
$ 17.33万 - 项目类别:
The development of an implicit measure of non-judgment of internal experiences
发展一种不评判内部经验的内隐衡量标准
- 批准号:
10007578 - 财政年份:2019
- 资助金额:
$ 17.33万 - 项目类别:
相似海外基金
Structural Racism, Pharmacy Closures and Disparities in Medication Adherence Among Older Adult Medicare Part-D Beneficiaries
结构性种族主义、药房关闭以及老年人医疗保险 D 部分受益人的药物依从性差异
- 批准号:
10568717 - 财政年份:2023
- 资助金额:
$ 17.33万 - 项目类别:
Medication Adherence and Cardio-Metabolic Control Indicators among Adult American Indians Receiving Tribal Health Services
接受部落卫生服务的成年美洲印第安人的药物依从性和心脏代谢控制指标
- 批准号:
10419967 - 财政年份:2022
- 资助金额:
$ 17.33万 - 项目类别:
Medication Adherence and Cardio-Metabolic Control Indicators among Adult American Indians Receiving Tribal Health Services
接受部落卫生服务的成年美洲印第安人的药物依从性和心脏代谢控制指标
- 批准号:
10592441 - 财政年份:2022
- 资助金额:
$ 17.33万 - 项目类别:
Leveraging Technology to Improve Medication Adherence in Adolescent and Young Adult Kidney or Liver Transplant Recipients
利用技术提高青少年和年轻肾移植或肝移植受者的药物依从性
- 批准号:
10369750 - 财政年份:2021
- 资助金额:
$ 17.33万 - 项目类别:
Leveraging Technology to Improve Medication Adherence in Adolescent and Young Adult Kidney or Liver Transplant Recipients
利用技术提高青少年和年轻肾移植或肝移植受者的药物依从性
- 批准号:
10633248 - 财政年份:2021
- 资助金额:
$ 17.33万 - 项目类别:
Leveraging Technology to Improve Medication Adherence in Adolescent and Young Adult Kidney or Liver Transplant Recipients
利用技术提高青少年和年轻肾移植或肝移植受者的药物依从性
- 批准号:
10487516 - 财政年份:2021
- 资助金额:
$ 17.33万 - 项目类别:
Mhealth for Pre-exposure Prophylaxis Adherence by Young Adult MSM
Mhealth 促进年轻 MSM 遵守暴露前预防
- 批准号:
10228564 - 财政年份:2018
- 资助金额:
$ 17.33万 - 项目类别:
Mhealth for Pre-exposure Prophylaxis Adherence by Young Adult MSM
Mhealth 促进年轻 MSM 遵守暴露前预防
- 批准号:
9347041 - 财政年份:2017
- 资助金额:
$ 17.33万 - 项目类别:
Mindfulness training with HIV-positive youth and adult family members to improve treatment adherence
对艾滋病毒呈阳性的青少年和成年家庭成员进行正念训练,以提高治疗依从性
- 批准号:
9480702 - 财政年份:2016
- 资助金额:
$ 17.33万 - 项目类别:
Mindfulness training with HIV-positive youth and adult family members to improve treatment adherence
对艾滋病毒呈阳性的青少年和成年家庭成员进行正念训练,以提高治疗依从性
- 批准号:
9906853 - 财政年份:2016
- 资助金额:
$ 17.33万 - 项目类别:














{{item.name}}会员




