Core F: Biomarker Core

生物标志物核心-核心F：项目摘要/摘要 约翰霍普金斯阿尔茨海默病研究中心(JHADRC)的生物标志物核心(核心F)是 负责收集和共享从特征良好的参与者那里收集的生物流体和成像数据 在JHADRC，并将这些资源提供给在Johns从事ADRD工作的调查人员 霍普金斯大学和其他地方。为了实现这些目标，Biomarker核心将专注于以下几个方面 五项任务：(1)从JHADRC登记的受试者收集和储存生物检疫试剂，包括血液和 脑脊液；(2)获取和存储受试者的磁共振成像扫描(MRI) 在JHADRC中，并存储在项目中获得的核磁共振扫描和正电子发射断层扫描(PET)扫描 与JHADRC合作；(3)完成质量控制程序和MRI扫描处理 通过JHADRC获得的扫描；(4)将这些扫描和标本分发给合格的调查人员 按照既定程序对内对外；(5)提供培训和 向研究人员和成员介绍这些生物标志物及其在ADRD中的重要性的教育材料 社区。

BIOMARKER CORE - CORE F: PROJECT SUMMARY/ABSTRACT The Biomarker Core (Core F) of the Johns Hopkins Alzheimer's Disease Research Center (JHADRC) is responsible for collecting and sharing biofluid and imaging data collected from well-characterized participants in the JHADRC, and for making these resources available to investigators working on ADRD at Johns Hopkins University and elsewhere. To accomplish these goals, the Biomarker Core will focus on the following five tasks: (1) to collect and store biospecimens from subjects enrolled in the JHADRC, including blood and cerebrospinal fluid; (2) to acquire and store magnetic resonance imaging scans (MRI) from subjects enrolled in the JHADRC, and to store MRI scans and positron emission tomography (PET) scans acquired in projects associated with the JHADRC; (3) to complete quality control procedures and scan processing on the MRI scans acquired through the JHADRC; (4) to distribute these scans and specimens to qualified investigators both internally and externally, according to established procedures, and; (5) to provide training and educational materials about these biomarkers and their importance in ADRD to researchers and members of the community.