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中文摘要
翻译
生物标志物核心-核心F:项目总结/摘要 约翰霍普金斯阿尔茨海默病研究中心(JHADRC)的生物标志物核心(核心F)是 负责收集和共享从特征良好的参与者收集的生物流体和成像数据 在JHADRC,并使这些资源提供给在约翰斯从事ADRD研究的调查人员 霍普金斯大学和其他地方。为了实现这些目标,生物标志物核心将侧重于以下方面 五项任务:(1)从JHADRC入组的受试者中采集和储存生物标本,包括血液, 脑脊液;(2)采集并存储入组受试者的磁共振成像扫描(MRI) 在JHADRC中,并存储在项目中获得的MRI扫描和正电子发射断层扫描(PET) 与JHADRC相关;(3)完成MRI的质量控制程序和扫描处理 通过JHADRC获得的扫描;(4)将这些扫描和标本分发给合格的研究人员 (5)根据既定程序,在内部和外部提供培训, 关于这些生物标志物及其在ADRD中的重要性的教育材料, 社会各界
英文摘要
BIOMARKER CORE - CORE F: PROJECT SUMMARY/ABSTRACT The Biomarker Core (Core F) of the Johns Hopkins Alzheimer's Disease Research Center (JHADRC) is responsible for collecting and sharing biofluid and imaging data collected from well-characterized participants in the JHADRC, and for making these resources available to investigators working on ADRD at Johns Hopkins University and elsewhere. To accomplish these goals, the Biomarker Core will focus on the following five tasks: (1) to collect and store biospecimens from subjects enrolled in the JHADRC, including blood and cerebrospinal fluid; (2) to acquire and store magnetic resonance imaging scans (MRI) from subjects enrolled in the JHADRC, and to store MRI scans and positron emission tomography (PET) scans acquired in projects associated with the JHADRC; (3) to complete quality control procedures and scan processing on the MRI scans acquired through the JHADRC; (4) to distribute these scans and specimens to qualified investigators both internally and externally, according to established procedures, and; (5) to provide training and educational materials about these biomarkers and their importance in ADRD to researchers and members of the community.
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Visual hallucinations and memory impairment in Parkinson's Disease: The role of hippocampal networks
  • 批准号:
    10668429
  • 项目类别:
  • 资助金额:
    $59.29万
  • 财政年份:
    2021
  • 负责人:
    Arnold Bakker
  • 依托单位:
Visual hallucinations and memory impairment in Parkinson's Disease: The role of hippocampal networks
  • 批准号:
    10471165
  • 项目类别:
  • 资助金额:
    $61.5万
  • 财政年份:
    2021
  • 负责人:
    Arnold Bakker
  • 依托单位:
Visual hallucinations and memory impairment in Parkinson's Disease: The role of hippocampal networks
  • 批准号:
    10025308
  • 项目类别:
  • 资助金额:
    $66.96万
  • 财政年份:
    2021
  • 负责人:
    Arnold Bakker
  • 依托单位:
Imaging the alpha7 nicotinic acetylcholine receptor in mild cognitive impairment
  • 批准号:
    10094179
  • 项目类别:
  • 资助金额:
    $78.17万
  • 财政年份:
    2020
  • 负责人:
    Arnold Bakker
  • 依托单位:
国内基金
海外基金
新型F-18标记香豆素衍生物PET探针的研制及靶向Alzheimer's Disease 斑块显像研究
  • 批准号:
    81000622
  • 项目类别:
    青年科学基金项目
  • 资助金额:
    20.0万元
  • 批准年份:
    2010
  • 负责人:
    梁胜
  • 依托单位:
阿尔茨海默病(Alzheimer's disease,AD)动物模型构建的分子机理研究
  • 批准号:
    31060293
  • 项目类别:
    地区科学基金项目
  • 资助金额:
    26.0万元
  • 批准年份:
    2010
  • 负责人:
    郭亚芬
  • 依托单位:
跨膜转运蛋白21(TMP21)对引起阿尔茨海默病(Alzheimer'S Disease)的γ分泌酶的作用研究