The Pediatric Advanced Cancer Experience (PACE): Measuring Quality of End-of-Life Care for Children with Cancer
儿科晚期癌症经验 (PACE):衡量癌症儿童临终关怀的质量
基本信息
- 批准号:10376885
- 负责人:
- 金额:$ 22.03万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2021
- 资助国家:美国
- 起止时间:2021-04-01 至 2026-03-31
- 项目状态:未结题
- 来源:
- 关键词:AcademyAddressAdultAdvanced Malignant NeoplasmAdvisory CommitteesArtificial IntelligenceAwardBereavementCaregiversCaringCessation of lifeChildChild CareChildhoodClinicalCognitiveCohort StudiesCommunicationDataData CollectionData SourcesDevelopment PlansElectronic Health RecordEvaluationFaceFamilyFoundationsGoalsHealthcareHospitalizationIncentivesIntubationInvestigationKnowledgeLeadershipLength of StayLibrariesLifeMalignant Childhood NeoplasmMalignant NeoplasmsManualsMeasurementMeasuresMedicineMentorshipMethodsMinorityNatural Language ProcessingNon-accidentalOutcomePainPalliative CareParentsPatient Outcomes AssessmentsPatientsProceduresProcessProcess MeasurePropertyProviderPsychometricsQuality of CareQuestionnaire DesignsQuestionnairesReportingResearchResearch PersonnelResearch TechnicsResourcesSamplingScienceStructureSurveysSymptomsTestingTrainingTraining ActivityWorkbasecancer carecare deliverycareercareer developmentcohortdesigndesign verificationend of lifeend of life careevidence baseexperienceexperimental studyhealth care service utilizationhospice environmentimprovedmultimodalitynovelpatient orientedpreferenceprogramsprospectiveskillstooltrend
项目摘要
PROJECT SUMMARY
Although cure rates for childhood cancer have increased over several decades, cancer remains the leading
cause of non-accidental death in children. Yet, there are no existing quality measures to define optimal end-of-
life care (EOLC) for children with cancer. A lack of standards for EOLC contributes to high healthcare utilization
for children with advanced, incurable cancer, as well as widely variable palliative care provision. For adults with
cancer, high quality EOLC is defined at least in part by measures to reduce use of intensive healthcare
resources, such as avoidance of hospital stays in the last weeks of life and prompt referral to hospice. In
contrast, attributes of high quality EOLC for children with cancer have not been previously elucidated. To
address this gap in knowledge, the overall objectives of this proposal are to prioritize family-centered quality
measures for EOLC and to pioneer complementary approaches to assess care quality for children with
advanced cancer. Specific aims are to: (1) establish a priority list of EOLC quality measures, from the
perspective of parents of children with cancer; (2) characterize EOLC process measures for children who died
of cancer, using natural language processing in electronic health records; and (3) develop and pilot the
“Pediatric Advanced Cancer Experience” (PACE) questionnaire to prospectively appraise care quality for
children with advanced cancer. Completion of these aims will lay the foundation for the first multi-center, multi-
modal evaluation of end-of-life care quality in children with cancer. The long term goal of Dr. Ananth’s research
program is to build a platform for systematically measuring, reporting, and incentivizing high quality EOLC in
children with cancer, facilitating goal-concordant care delivery. Through the proposed research, Dr. Ananth
seeks to advance the science of measuring EOLC quality in childhood cancer. Dr. Ananth is supported by an
outstanding mentorship team and scientific advisory committee, with substantial expertise spanning patient-
reported outcomes, artificial intelligence-based techniques for research, and pediatric palliative care
investigation. Dr. Ananth will pursue formal training in patient-centered quality measurement, natural language
processing, and questionnaire design and validation, concurrently building skills in leadership of a multi-center
consortium. Collectively, the research in this proposal and career development plan will amply prepare her for
an independent career focused on enhancing quality of care for children with advanced, incurable cancer.
项目摘要
尽管儿童癌症的治愈率在过去几十年中有所提高,但癌症仍然是儿童癌症的主要病因。
儿童非意外死亡的原因。然而,没有现有的质量措施来定义最佳的结束-
癌症儿童的生活护理(EOLC)。缺乏EOLC标准导致医疗保健利用率高
为患有晚期、无法治愈的癌症的儿童提供的姑息治疗,以及各种各样的姑息治疗。治疗成人
在癌症中,高质量的EOLC至少部分地通过减少使用强化医疗保健的措施来定义
在生命的最后几周避免住院和及时转诊到临终关怀机构。在
相反,先前尚未阐明用于患有癌症的儿童的高质量EOLC的属性。到
为了弥补这一知识差距,本提案的总体目标是优先考虑以家庭为中心的质量
采取措施,并开创补充方法,评估患有
晚期癌症具体目标是:(1)建立平等机会法律委员会质量措施的优先清单,
癌症儿童父母的观点;(2)描述死亡儿童的EOLC过程措施
在电子健康记录中使用自然语言处理;以及(3)开发和试点
“儿科晚期癌症经验”(PACE)问卷,用于前瞻性评估
患有晚期癌症的儿童这些目标的完成,将为我国第一个多中心、多中心、
癌症儿童临终关怀质量的模式评价Ananth博士研究的长期目标是
计划是建立一个平台,系统地衡量,报告和激励高质量的EOLC,
癌症儿童,促进目标一致的护理提供。通过这项研究,Ananth博士
旨在推进测量儿童癌症EOLC质量的科学。Ananth博士由一位
优秀的导师团队和科学咨询委员会,具有丰富的专业知识,涵盖患者-
报告的结果,基于人工智能的研究技术和儿科姑息治疗
调查Ananth博士将接受以患者为中心的质量测量、自然语言
加工、问卷设计与验证,同时构建多中心的领导技能
财团总的来说,本提案和职业发展计划中的研究将为她做好充分的准备,
一个独立的职业生涯,专注于提高护理质量的儿童与先进的,不可治愈的癌症。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Prasanna J Ananth其他文献
Prasanna J Ananth的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Prasanna J Ananth', 18)}}的其他基金
The Pediatric Advanced Cancer Experience (PACE): Measuring Quality of End-of-Life Care for Children with Cancer
儿科晚期癌症经验 (PACE):衡量癌症儿童临终关怀的质量
- 批准号:
10605222 - 财政年份:2021
- 资助金额:
$ 22.03万 - 项目类别:
The Pediatric Advanced Cancer Experience (PACE): Measuring Quality of End-of-Life Care for Children with Cancer
儿科晚期癌症经验 (PACE):衡量癌症儿童临终关怀的质量
- 批准号:
10190336 - 财政年份:2021
- 资助金额:
$ 22.03万 - 项目类别:
相似海外基金
Rational design of rapidly translatable, highly antigenic and novel recombinant immunogens to address deficiencies of current snakebite treatments
合理设计可快速翻译、高抗原性和新型重组免疫原,以解决当前蛇咬伤治疗的缺陷
- 批准号:
MR/S03398X/2 - 财政年份:2024
- 资助金额:
$ 22.03万 - 项目类别:
Fellowship
Re-thinking drug nanocrystals as highly loaded vectors to address key unmet therapeutic challenges
重新思考药物纳米晶体作为高负载载体以解决关键的未满足的治疗挑战
- 批准号:
EP/Y001486/1 - 财政年份:2024
- 资助金额:
$ 22.03万 - 项目类别:
Research Grant
CAREER: FEAST (Food Ecosystems And circularity for Sustainable Transformation) framework to address Hidden Hunger
职业:FEAST(食品生态系统和可持续转型循环)框架解决隐性饥饿
- 批准号:
2338423 - 财政年份:2024
- 资助金额:
$ 22.03万 - 项目类别:
Continuing Grant
Metrology to address ion suppression in multimodal mass spectrometry imaging with application in oncology
计量学解决多模态质谱成像中的离子抑制问题及其在肿瘤学中的应用
- 批准号:
MR/X03657X/1 - 财政年份:2024
- 资助金额:
$ 22.03万 - 项目类别:
Fellowship
CRII: SHF: A Novel Address Translation Architecture for Virtualized Clouds
CRII:SHF:一种用于虚拟化云的新型地址转换架构
- 批准号:
2348066 - 财政年份:2024
- 资助金额:
$ 22.03万 - 项目类别:
Standard Grant
The Abundance Project: Enhancing Cultural & Green Inclusion in Social Prescribing in Southwest London to Address Ethnic Inequalities in Mental Health
丰富项目:增强文化
- 批准号:
AH/Z505481/1 - 财政年份:2024
- 资助金额:
$ 22.03万 - 项目类别:
Research Grant
ERAMET - Ecosystem for rapid adoption of modelling and simulation METhods to address regulatory needs in the development of orphan and paediatric medicines
ERAMET - 快速采用建模和模拟方法的生态系统,以满足孤儿药和儿科药物开发中的监管需求
- 批准号:
10107647 - 财政年份:2024
- 资助金额:
$ 22.03万 - 项目类别:
EU-Funded
BIORETS: Convergence Research Experiences for Teachers in Synthetic and Systems Biology to Address Challenges in Food, Health, Energy, and Environment
BIORETS:合成和系统生物学教师的融合研究经验,以应对食品、健康、能源和环境方面的挑战
- 批准号:
2341402 - 财政年份:2024
- 资助金额:
$ 22.03万 - 项目类别:
Standard Grant
Ecosystem for rapid adoption of modelling and simulation METhods to address regulatory needs in the development of orphan and paediatric medicines
快速采用建模和模拟方法的生态系统,以满足孤儿药和儿科药物开发中的监管需求
- 批准号:
10106221 - 财政年份:2024
- 资助金额:
$ 22.03万 - 项目类别:
EU-Funded
Recite: Building Research by Communities to Address Inequities through Expression
背诵:社区开展研究,通过表达解决不平等问题
- 批准号:
AH/Z505341/1 - 财政年份:2024
- 资助金额:
$ 22.03万 - 项目类别:
Research Grant