80 Years and Older Vision & Hearing Important Persons Project (80VIP)

80岁及以上的视力

• 批准号: 10380067
• 负责人: Steven L Mansberger
• 金额: $ 23.52万
• 依托单位: LEGACY EMANUEL HOSPITAL AND HEALTH CENTER
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-04-01 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10380067
• 关键词: Address; Adult; African American; Age; Aged, 80 and over; Applications Grants; Biometry; Black American; Blindness; Caregiver Burden; Caregivers; Caring; Categories; Cessation of life; Clinical Trials; Communities; Country; Data; Development; Educational process of instructing; Effectiveness; Elderly; Enrollment; Equilibrium; Ethnic group; Evaluation; Funding Mechanisms; Future; General Population; Goals; Grant; Health; Health Care Costs; Health Planning; Health Resources; Hearing; Hispanic; Impaired cognition; Income; Individual; Informed Consent; Infrastructure; Institutionalization; Intervention; Knowledge; Latino; Link; Longevity; Manuals; Measures; Mental Depression; Methods; Minority Groups; Morbidity - disease rate; Multicenter Studies; Participant; Patient Outcomes Assessments; Patients; Persons; Policies; Population; Population Research; Population Study; Presbycusis; Prevalence; Prevalence Study; Procedures; Protocols documentation; Public Health; Quality of life; Research; Risk; Scientist; Sensory; Series; Special Population; Statistical Data Interpretation; Surveys; Testing; Transportation; Treatment Effectiveness; U-Series Cooperative Agreements; United States National Institutes of Health; Vision; Visual; Visual impairment; age group; age related; aged; burden of illness; cognitive function; cost; cost effectiveness; economic cost; equilibration disorder; experience; fall risk; functional outcomes; hearing impairment; impaired capacity; instrumentation; multi-ethnic; neurosensory; novel; older patient; population based; prevent; racial and ethnic; recruit

Project Summary/Abstract Previous prevalence studies include only small and infrequent estimates of vision, hearing, balance loss or dual sensory loss (DSL) in older adults over aged 80 years, which creates a large gap in knowledge in this important age group. This age group will increase by 600% in the next 30 years, an increase faster than any other age strata, or minority group. Many older patients admitted into institutionalized care have high proportions of untreated VL/HL/DSL. Unfortunately, little data exists on the effectiveness of treating VL/HL/DSL to decrease morbidity, increase quality of life, and decrease caregiver burden and cost in this susceptible age group. This demonstrates a need to understand the prevalence and impact of undiagnosed VL/HL/DSL in community dwelling older adults. Age-related hearing and vision impairment will each rank within the top 10 burdens of disease in middle- and high-income countries in the next 20 years. This evaluation of older persons fits with the National Institutes of Health's new "Inclusion Across the Lifespan" policy that was implemented in January 2019. The R34 planning grant is to support the development of a detailed infrastructure for a future ‘80 Years and Older Vision & Hearing Important Persons Project (80VIP)’ under the UG1 Cooperative Agreement funding mechanism. This special population (age >80 years) is rarely included in population-based prevalence surveys or clinical trials, and may require more effort, or new methods to recruit and enroll participants when compared to previous studies. We will also develop a comprehensive manual of procedures, which includes standards for collecting ocular and biometric data, includes new instrumentation, and allows comparisons with previous groundbreaking prevalence surveys. We will also evaluate the burden, feasibility, and suitability of the protocol from the perspective of key stakeholders, which increases the likelihood of a successfully transition into a larger UG1 study; and we will develop a statistical analysis plan that addresses all of the proposed future hypotheses. The study team has the expertise to conduct this proposal, and move this planning grant proposal toward a successful UG1 application. In the future, the experiences and data from this proposal will help plan health resources requirements in the future, and interventions to augment healthy living, prevent morbidity such as institutionalized care, and reduce the high economic costs of vision and hearing loss.

项目摘要/摘要 以前的患病率研究只包括对视力、听力、平衡丧失或 80岁以上老年人的双重感觉丧失(DSL)，这导致在这方面的知识存在很大差距 重要的年龄段。在接下来的30年里，这一年龄段将增长600%，增长速度比以往任何时候都快 其他年龄阶层，或少数群体。许多住进机构护理的老年患者都有很高的 未处理的VL/HL/DSL的比例。不幸的是，关于治疗VL/HL/DSL的有效性的数据很少 在这个易受感染的年龄，减少发病率，提高生活质量，减少照顾者的负担和成本 一群人。这表明有必要了解未诊断的VL/HL/DSL在 居住在社区的老年人。与年龄相关的听力和视力障碍将分别跻身前十名 未来20年中高收入国家的疾病负担。这项对老年人的评估 符合美国国立卫生研究院于#年实施的新的“终身包容”政策 2019年1月。 R34规划拨款是为了支持未来80年详细基础设施的发展和 UG1合作协议资助下的老年人视力和听力重要人士项目(80VIP) 机制。这一特殊人群(80岁)很少包括在基于人口的患病率调查中 或临床试验，可能需要更多的努力，或者需要新的方法来招募和招募参与者 之前的研究。我们还将制定一份全面的程序手册，其中包括以下标准 收集眼睛和生物特征数据，包括新的仪器，并允许与以前的比较 开创性的流行率调查。我们还将评估该协议的负担、可行性和适宜性 从关键利益相关者的角度来看，这增加了成功过渡到 更大的UG1研究；我们将制定一项统计分析计划，以应对所有拟议的未来 假设。研究小组有专业知识进行这项建议，并提出这项规划拨款建议 朝着一个成功的UG1申请迈进。在未来，这项提案的经验和数据将有助于规划 未来的卫生资源需求，以及加强健康生活、预防发病率的干预措施 例如制度化护理，并减少视力和听力损失的高昂经济成本。