80 Years and Older Vision & Hearing Important Persons Project (80VIP)

80岁及以上的视力

• 批准号: 10380067
• 负责人: Steven L Mansberger
• 金额: $ 23.52万
• 依托单位: LEGACY EMANUEL HOSPITAL AND HEALTH CENTER
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-04-01 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10380067
• 关键词: Address; Adult; African American; Age; Aged, 80 and over; Applications Grants; Biometry; Black American; Blindness; Caregiver Burden; Caregivers; Caring; Categories; Cessation of life; Clinical Trials; Communities; Country; Data; Development; Educational process of instructing; Effectiveness; Elderly; Enrollment; Equilibrium; Ethnic group; Evaluation; Funding Mechanisms; Future; General Population; Goals; Grant; Health; Health Care Costs; Health Planning; Health Resources; Hearing; Hispanic; Impaired cognition; Income; Individual; Informed Consent; Infrastructure; Institutionalization; Intervention; Knowledge; Latino; Link; Longevity; Manuals; Measures; Mental Depression; Methods; Minority Groups; Morbidity - disease rate; Multicenter Studies; Participant; Patient Outcomes Assessments; Patients; Persons; Policies; Population; Population Research; Population Study; Presbycusis; Prevalence; Prevalence Study; Procedures; Protocols documentation; Public Health; Quality of life; Research; Risk; Scientist; Sensory; Series; Special Population; Statistical Data Interpretation; Surveys; Testing; Transportation; Treatment Effectiveness; U-Series Cooperative Agreements; United States National Institutes of Health; Vision; Visual; Visual impairment; age group; age related; aged; burden of illness; cognitive function; cost; cost effectiveness; economic cost; equilibration disorder; experience; fall risk; functional outcomes; hearing impairment; impaired capacity; instrumentation; multi-ethnic; neurosensory; novel; older patient; population based; prevent; racial and ethnic; recruit

Project Summary/Abstract Previous prevalence studies include only small and infrequent estimates of vision, hearing, balance loss or dual sensory loss (DSL) in older adults over aged 80 years, which creates a large gap in knowledge in this important age group. This age group will increase by 600% in the next 30 years, an increase faster than any other age strata, or minority group. Many older patients admitted into institutionalized care have high proportions of untreated VL/HL/DSL. Unfortunately, little data exists on the effectiveness of treating VL/HL/DSL to decrease morbidity, increase quality of life, and decrease caregiver burden and cost in this susceptible age group. This demonstrates a need to understand the prevalence and impact of undiagnosed VL/HL/DSL in community dwelling older adults. Age-related hearing and vision impairment will each rank within the top 10 burdens of disease in middle- and high-income countries in the next 20 years. This evaluation of older persons fits with the National Institutes of Health's new "Inclusion Across the Lifespan" policy that was implemented in January 2019. The R34 planning grant is to support the development of a detailed infrastructure for a future ‘80 Years and Older Vision & Hearing Important Persons Project (80VIP)’ under the UG1 Cooperative Agreement funding mechanism. This special population (age >80 years) is rarely included in population-based prevalence surveys or clinical trials, and may require more effort, or new methods to recruit and enroll participants when compared to previous studies. We will also develop a comprehensive manual of procedures, which includes standards for collecting ocular and biometric data, includes new instrumentation, and allows comparisons with previous groundbreaking prevalence surveys. We will also evaluate the burden, feasibility, and suitability of the protocol from the perspective of key stakeholders, which increases the likelihood of a successfully transition into a larger UG1 study; and we will develop a statistical analysis plan that addresses all of the proposed future hypotheses. The study team has the expertise to conduct this proposal, and move this planning grant proposal toward a successful UG1 application. In the future, the experiences and data from this proposal will help plan health resources requirements in the future, and interventions to augment healthy living, prevent morbidity such as institutionalized care, and reduce the high economic costs of vision and hearing loss.

项目概要/摘要 以前的患病率研究仅包括对视力、听力、平衡丧失或 80岁以上老年人的双重感觉丧失（DSL），这造成了这方面的巨大知识差距 重要的年龄段。未来30年，这个年龄段的人口将增长600%，增长速度超过任何年龄段 其他年龄层或少数群体。许多接受机构护理的老年患者患有高 未经处理的 VL/HL/DSL 的比例。不幸的是，关于治疗 VL/HL/DSL 有效性的数据很少 在这个易受影响的年龄段降低发病率、提高生活质量并减轻护理人员的负担和成本 团体。这表明需要了解未确诊的 VL/HL/DSL 的患病率和影响 社区居住的老年人。与年龄相关的听力和视力障碍将分别进入前十名 未来 20 年中等收入和高收入国家的疾病负担。这个对老年人的评价 符合美国国立卫生研究院于 2017 年实施的新“包容性贯穿生命周期”政策 2019 年 1 月。 R34 规划拨款旨在支持未来“80 年和 UG1合作协议资助下的老年视力和听力重要人士项目（80VIP）’ 机制。这一特殊人群（年龄>80岁）很少被纳入基于人群的患病率调查 或临床试验，与相比，可能需要更多的努力，或新的方法来招募和登记参与者 到以前的研究。我们还将制定一份全面的程序手册，其中包括以下标准： 收集视觉和生物识别数据，包括新仪器，并允许与以前的比较 开创性的患病率调查。我们还将评估该协议的负担、可行性和适用性 从主要利益相关者的角度来看，这增加了成功转型为 更大规模的 UG1 研究；我们将制定一个统计分析计划来解决所有拟议的未来 假设。研究团队拥有执行该提案并推动该规划拨款提案的专业知识 走向成功的 UG1 申请。今后，该提案的经验和数据将有助于规划 未来的卫生资源需求以及增强健康生活、预防发病的干预措施 例如机构化护理，并减少视力和听力损失的高昂经济成本。