A prospective examination of sleep, eating behavior, and weight gain among overweight adults

对超重成年人的睡眠、饮食行为和体重增加的前瞻性检查

• 批准号: 10379919
• 负责人: Leah A Irish
• 金额: $ 16.2万
• 依托单位: SANFORD RESEARCH NORTH
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-04-01 至 2026-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10379919
• 关键词: Achievement; Affect; American; Attenuated; Behavioral; Binge Eating; Body Composition; Body Weight; Body Weight Changes; Body Weight decreased; Body fat; Buffers; Calories; Centers of Research Excellence; Chronic Disease; Clinical; Cognitive; Consumption; Cost of Illness; Cross-Sectional Studies; Decision Making; Development; Eating; Eating Behavior; Eating Disorders; Fatty acid glycerol esters; Food; Health Resources; Impaired cognition; Impairment; Individual; Individual Differences; Interview; Knowledge; Link; Literature; Maintenance; Measures; Mediating; Modeling; Neurocognitive; Obesity; Overweight; Participant; Patient Self-Report; Process; Prospective Studies; Public Health; Quality of life; Reporting; Research; Resource Allocation; Resources; Risk; Role; Sampling; Short-Term Memory; Sleep; Sleep Deprivation; Sodium; Testing; Time; Visit; Weight; Weight Gain; Weight maintenance regimen; actigraphy; adult obesity; biobehavior; cognitive control; cognitive function; cognitive process; cognitive task; design; diaries; dietary; disability; executive function; experience; flexibility; fruits and vegetables; high body mass index; improved; insight; mortality; mortality risk; novel; obesity prevention; obesity treatment; overweight adults; prevent; prospective; sleep behavior; trait

A prospective examination of sleep, eating behavior, and weight gain among overweight adults PROJECT SUMMARY/ABSTRACT Approximately 70% of American adults are overweight or obese, which confers increased risk for reduced quality of life, disability, chronic disease, and mortality. Efforts to reduce the public health burden of obesity have identified bio-behavioral factors involved in the development and maintenance of high body weight. Sleep has emerged as a particularly robust predictor of weight gain and obesity in both prospective and cross- sectional research, but the mechanisms linking sleep and weight gain have not been adequately defined. The purpose of the proposed study is to examine actigraphy-assessed sleep duration as a prospective predictor of binge eating behavior and the extent to which binge eating mediates the relationship between sleep duration and weight gain and body composition over one year among overweight and obese adults. Further, executive function (I.e., inhibitory control, working memory, set-shifting, planning, decision making) as measured by a neurocognitive task battery will be examined as a moderator in the relationship between sleep and binge eating. As short sleep duration is associated with deficits in executive function, we hypothesize that higher trait levels of executive function will attenuate the effect of short sleep duration on binge eating. Achievement of our study aims will provide novel insight into the role of disordered eating behavior as a mechanism linking sleep and obesity and elucidate the extent to which executive function may affect sleep’s impact on eating behavior and weight gain. The knowledge gained from this study has the potential to inform obesity prevention or intervention efforts and identify vulnerable individuals which allows for more strategic allocation of public health resources.

超重成人睡眠、饮食行为和体重增加的前瞻性研究 项目总结/摘要 大约70%的美国成年人超重或肥胖，这增加了减少肥胖的风险。 生活质量、残疾、慢性病和死亡率。努力减轻肥胖症的公共卫生负担 已经确定了与高体重的发展和维持有关的生物行为因素。 在前瞻性和交叉研究中，睡眠已经成为体重增加和肥胖的一个特别有力的预测因素。 虽然睡眠与体重增加之间的关系已被广泛研究，但其机制尚未得到充分的界定。的 这项研究的目的是检查腕动记录仪评估的睡眠持续时间作为一个前瞻性的预测因子， 暴饮暴食行为和暴饮暴食在多大程度上介导睡眠持续时间之间的关系 以及超重和肥胖成年人一年内的体重增加和身体成分。此外，行政 函数（即，抑制控制、工作记忆、定势转换、计划、决策）， 神经认知任务组合将作为睡眠和狂欢之间关系的调节剂进行检查 吃由于睡眠时间短与执行功能缺陷有关，我们假设， 执行功能水平会减弱睡眠时间短对暴饮暴食的影响。实现 我们的研究目的将提供一个新的视角来了解饮食失调行为的作用， 睡眠和肥胖，并阐明在何种程度上执行功能可能会影响睡眠对饮食的影响 行为和体重增加。从这项研究中获得的知识有可能为肥胖预防提供信息 或干预努力，并确定脆弱的个人，以便更有战略性地分配公共资源， 卫生资源。