11/21 ABCD-USA Consortium: Research Project Site at UWM
11/21 ABCD-USA Consortium: Research Project Site at UWM
批准号:
10379430
负责人:
Christine L Larson
金额:
$118.95万
依托单位国家:
美国
项目类别:
财政年份:
2017
资助国家:
美国
项目状态:
未结题
起止时间:
2017-07-15 至 2027-03-31
关键词:
10 year oldAddressAdolescenceAdolescentAdultAffectAgeAlcohol consumptionAlcoholsAnxietyAthletic InjuriesBehaviorBehavioralBioinformaticsBiologicalBiological AssayBiologyBrainBrain imagingCaffeineCalendarCannabisChildChild HealthChildhoodClinical assessmentsCognitionCognitiveCommunitiesCountryDataData AnalysesDecision MakingDevelopmentEmotionalEnrollmentEnsureEnvironmentEnvironmental ExposureEnvironmental Risk FactorEpidemiologyEthicsEventFeeling suicidalFemaleFundingGeneticHealthImpairmentIndividualInformaticsInterviewLifeLinkLogisticsLongitudinal StudiesMental DepressionMental HealthMental disordersMethodologyMethodsMonitorNeurocognitionNeurocognitiveNeuropsychological TestsOccupationsOutcomeParentsParticipantPathway interactionsPersonsPhysical activityProcessProtocols documentationPsychopathologyRegistriesResearchResearch PersonnelResearch Project GrantsResource InformaticsResourcesRiskRoleSamplingSchoolsScienceSecureSeveritiesSiblingsSiteSleepSocial FunctioningSocial isolationSpecific qualifier valueSportsStandardizationSymptomsTechnologyTeenagersTelephoneTextTimeTobaccoTobacco useTrainingTraumatic Brain InjuryTriplet Multiple BirthTwin Multiple BirthUnited StatesVideo GamesYouthadolescent substance useadverse outcomecognitive developmentcognitive testingcohortcollegedesignemerging adultemotional factorexperiencefollow-upgene interactioninformatics infrastructuremarijuana usemobile applicationmobile computingmultimodalityneurodevelopmentneuroimagingnovelparticipant retentionphysical conditioningrecruitrelating to nervous systemresearch and developmentresponseretention ratesleep patternsocialsocial mediasubstance usetemporal measurementtrendtv watchingvapingyoung adult
中文摘要
摘要:
--
青少年大脑认知发育研究所(ABCD)是世界上最大的大脑发育和儿童长期研究机构之一。
美国的卫生组织。美国的ABCD健康研究和研究联盟由遍布美国的21个健康研究中心组成。
信息协调中心、数据分析中心和全球信息学信息资源管理中心。这是该中心成立五年来的第一个五年。
RFA--DA--15--015,ABCD已经从该财团、欧洲和欧洲各地的11,878名9-10岁的儿童中招募了不同的样本。
他们将跟踪他们从青春期到青春期的生物发育和行为发育。
--
所有参与者都接受了最全面的脑部基线评估,包括最先进的脑部成像。
神经心理测试和生物分析,以及对物质使用、心理和健康、身体和健康的仔细评估。
以及文化和环境。每隔两年就会有类似的详细评估。临时评估是面对面的年度评估。
年中和年中的电话采访或移动应用程序评估将提供精细化的时间和时间解决方案。
随着时间的推移,发展趋势改变了人们的生活和生活事件,而对参与的青年和青少年来说,他们的负担是最小的。
家长们。他们做出了密集的努力,以确保绝大多数参与这项研究的参与者在整个过程中都能保持健康。
青春期及以后,到目前为止,儿童和青少年的留存率仍然非常高。我们的神经成像技术也在不断扩大。
对大脑发育的理解从童年到成年。我们使用这一技术和其他尖端技术。
技术,如ABCD,甚至可以确定不同类型的青少年教育体验(如体育、学校)的不同。
参与、参加课外活动、玩电子游戏、玩社交媒体、不健康的睡眠(睡眠模式、游戏和电子烟)。
与孩子们相互作用,并与他们相互作用,改变他们的生物学能力,从而影响他们的大脑发育和社会、行为。
学术、大学、健康、教育和其他教育成果。
--
数据、安全存储和私下与全球科学界共享的数据,将使调查人员能够:(1)描述。
个体的发展途径包括神经、认知、情绪、学习和学术功能、能力和能力。
影响因素;;(2)制定健康儿童大脑发育的国家标准;;(3)调查儿童和儿童的作用。
基因的交互作用和环境对儿童发育的影响;;(4)将研究身体活动、睡眠和屏幕是如何变化的。
时间,包括运动和损伤(包括创伤性和脑部损伤),以及其他影响大脑发育的健康经历;;(5)。
确定并复制从儿童时期到成年后影响心理健康状况的因素;;(6)。
刻画心理健康问题和物质使用之间的关系;;和(7)具体说明如何使用物质。
如大麻、酒精、酒精、烟草、酒精和咖啡因等对发育障碍的影响,以及神经、认知和心理的影响。
情绪、心理和环境因素会影响青少年使用毒品的风险。
英文摘要
Abstract
Adolescent Brain Cognitive Development (ABCD) is the largest long-term study of brain development and child
health in the United States. The ABCD Research Consortium consists of 21 research sites across the country,
a Coordinating Center, and a Data Analysis and Informatics Resource Center. In its first five years, under
RFA-DA-15-015, ABCD enrolled a diverse sample of 11,878 9-10 year olds from across the consortium, and
will track their biological and behavioral development through adolescence into young adulthood.
All participants received a comprehensive baseline assessment, including state-of-the-art brain imaging,
neuropsychological testing, bioassays, careful assessment of substance use, mental health, physical health,
and culture and environment. A similar detailed assessment recurs every 2 years. Interim in-person annual
interviews and mid-year telephone or mobile app assessments provide refined temporal resolution of
developmental changes and life events that occur over time with minimal burden to participating youth and
parents. Intensive efforts are made to keep the vast majority of participants involved with the study through
adolescence and beyond, and retention rates thus far are very high. Neuroimaging has expanded our
understanding of brain development from childhood into adulthood. Using this and other cutting-edge
technologies, ABCD can determine how different kinds of youth experiences (such as sports, school
involvement, extracurricular activities, videogames, social media, unhealthy sleep patterns, and vaping)
interact with each other and with a child’s changing biology to affect brain development and social, behavioral,
academic, health, and other outcomes.
Data, securely and privately shared with the scientific community, will enable investigators to: (1) describe
individual developmental pathways in terms of neural, cognitive, emotional, and academic functioning, and
influencing factors;; (2) develop national standards of healthy brain development;; (3) investigate the roles and
interaction of genes and the environment on development;; (4) examine how physical activity, sleep, screen
time, sports injuries (including traumatic brain injuries), and other experiences influence brain development;; (5)
determine and replicate factors that influence mental health from childhood to young adulthood;; (6)
characterize relationships between mental health and substance use;; and (7) specify how use of substances
such as cannabis, alcohol, tobacco, and caffeine affects developmental outcomes, and how neural, cognitive,
emotional, and environmental factors influence the risk for adolescent substance use.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
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批准号:10431320
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批准号:10489823
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资助金额:$72.21万
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资助金额:$65.78万
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批准号:9981163
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资助金额:$94.21万
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财政年份:2017
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负责人:Christine L Larson
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依托单位:
11/21 ABCD-USA Consortium: Research Project Site at UWM
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批准号:10594953
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资助金额:$118.82万
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财政年份:2017
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依托单位:
Acute Neurocognitive-affective Predictors of Chronic Post-trauma Outcomes
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批准号:9279251
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资助金额:$68.49万
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依托单位:
Acute Neurocognitive-affective Predictors of Chronic Post-trauma Outcomes
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批准号:9118338
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项目类别:
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资助金额:$65.92万
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财政年份:2015
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依托单位:
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批准号:8100450
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依托单位:
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批准号:8640968
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项目类别:
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资助金额:$17.47万
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财政年份:2010
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批准号:7893407
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资助金额:$16.52万
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依托单位:
Imaging genetics of extinction of conditioned fear responses in anxiety
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批准号:8353829
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项目类别:
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资助金额:$17.13万
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财政年份:2010
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依托单位:
Imaging genetics of extinction of conditioned fear responses in anxiety
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批准号:8438480
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资助金额:$17.29万
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财政年份:2010
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依托单位:
Chronometry of amygdala response to affective stimuli
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批准号:6913779
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项目类别:
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资助金额:$7.17万
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财政年份:2005
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负责人:Christine L Larson
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依托单位:
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批准号:6330233
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REGIONAL BRAIN FUNCTION AND EMOTIONAL REACTIVITY
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批准号:6126035
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财政年份:1999
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依托单位:
REGIONAL BRAIN FUNCTION AND EMOTIONAL REACTIVITY
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批准号:2642255
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财政年份:1998
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负责人:Christine L Larson
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依托单位:
海外基金