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11/21 ABCD-USA Consortium: Research Project Site at UWM

11/21 ABCD-USA Consortium: Research Project Site at UWM
11/21 ABCD-USA 联盟:UWM 研究项目现场
批准号:
10379430
负责人:
Christine L Larson
金额:
$118.95万
依托单位国家:
美国
项目类别:
财政年份:
2017
资助国家:
美国
项目状态:
未结题
起止时间:
2017-07-15 至 2027-03-31
关键词:
10 year oldAddressAdolescenceAdolescentAdultAffectAgeAlcohol consumptionAlcoholsAnxietyAthletic InjuriesBehaviorBehavioralBioinformaticsBiologicalBiological AssayBiologyBrainBrain imagingCaffeineCalendarCannabisChildChild HealthChildhoodClinical assessmentsCognitionCognitiveCommunitiesCountryDataData AnalysesDecision MakingDevelopmentEmotionalEnrollmentEnsureEnvironmentEnvironmental ExposureEnvironmental Risk FactorEpidemiologyEthicsEventFeeling suicidalFemaleFundingGeneticHealthImpairmentIndividualInformaticsInterviewLifeLinkLogisticsLongitudinal StudiesMental DepressionMental HealthMental disordersMethodologyMethodsMonitorNeurocognitionNeurocognitiveNeuropsychological TestsOccupationsOutcomeParentsParticipantPathway interactionsPersonsPhysical activityProcessProtocols documentationPsychopathologyRegistriesResearchResearch PersonnelResearch Project GrantsResource InformaticsResourcesRiskRoleSamplingSchoolsScienceSecureSeveritiesSiblingsSiteSleepSocial FunctioningSocial isolationSpecific qualifier valueSportsStandardizationSymptomsTechnologyTeenagersTelephoneTextTimeTobaccoTobacco useTrainingTraumatic Brain InjuryTriplet Multiple BirthTwin Multiple BirthUnited StatesVideo GamesYouthadolescent substance useadverse outcomecognitive developmentcognitive testingcohortcollegedesignemerging adultemotional factorexperiencefollow-upgene interactioninformatics infrastructuremarijuana usemobile applicationmobile computingmultimodalityneurodevelopmentneuroimagingnovelparticipant retentionphysical conditioningrecruitrelating to nervous systemresearch and developmentresponseretention ratesleep patternsocialsocial mediasubstance usetemporal measurementtrendtv watchingvapingyoung adult

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Abstract    Adolescent Brain Cognitive Development (ABCD) is the largest long-­term study of brain development and child  health in the United States. The ABCD Research Consortium consists of 21 research sites across the country,  a Coordinating Center, and a Data Analysis and Informatics Resource Center.  In its first five years, under  RFA-­DA-­15-­015, ABCD enrolled a diverse sample of 11,878 9-­10 year olds from across the consortium, and  will track their biological and behavioral development through adolescence into young adulthood.      All participants received a comprehensive baseline assessment, including state-­of-­the-­art brain imaging,  neuropsychological testing, bioassays, careful assessment of substance use, mental health, physical health,  and culture and environment.  A similar detailed assessment recurs every 2 years. Interim in-­person annual  interviews and mid-­year telephone or mobile app assessments provide refined temporal resolution of  developmental changes and life events that occur over time with minimal burden to participating youth and  parents. Intensive efforts are made to keep the vast majority of participants involved with the study through  adolescence and beyond, and retention rates thus far are very high. Neuroimaging has expanded our  understanding of brain development from childhood into adulthood. Using this and other cutting-­edge  technologies, ABCD can determine how different kinds of youth experiences (such as sports, school  involvement, extracurricular activities, videogames, social media, unhealthy sleep patterns, and vaping)  interact with each other and with a child’s changing biology to affect brain development and social, behavioral,  academic, health, and other outcomes.    Data, securely and privately shared with the scientific community, will enable investigators to: (1) describe  individual developmental pathways in terms of neural, cognitive, emotional, and academic functioning, and  influencing factors;; (2) develop national standards of healthy brain development;; (3) investigate the roles and  interaction of genes and the environment on development;; (4) examine how physical activity, sleep, screen  time, sports injuries (including traumatic brain injuries), and other experiences influence brain development;; (5)  determine and replicate factors that influence mental health from childhood to young adulthood;; (6)  characterize relationships between mental health and substance use;; and (7) specify how use of substances  such as cannabis, alcohol, tobacco, and caffeine affects developmental outcomes, and how neural, cognitive,  emotional, and environmental factors influence the risk for adolescent substance use.
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Neural Mechanisms of Response Inhibition Training for Obsessive-Compulsive Disorder and Related Conditions
  • 批准号:
    10431320
  • 项目类别:
  • 资助金额:
    $74.39万
  • 财政年份:
    2022
  • 负责人:
    Christine L Larson
  • 依托单位:
Risk and Resilience in Urban Black American Acute Trauma Survivors
  • 批准号:
    10379585
  • 项目类别:
  • 资助金额:
    $79.2万
  • 财政年份:
    2021
  • 负责人:
    Christine L Larson
  • 依托单位:
Risk and Resilience in Urban Black American Acute Trauma Survivors
  • 批准号:
    10489823
  • 项目类别:
  • 资助金额:
    $72.21万
  • 财政年份:
    2021
  • 负责人:
    Christine L Larson
  • 依托单位:
Risk and Resilience in Urban Black American Acute Trauma Survivors
  • 批准号:
    10687026
  • 项目类别:
  • 资助金额:
    $65.78万
  • 财政年份:
    2021
  • 负责人:
    Christine L Larson
  • 依托单位:
海外基金