NICHD maternal fetal medicine units network

摘要 该提案描述了俄亥俄州立大学(OSU)中心继续参与的申请 在尤尼斯·肯尼迪·施莱弗、NICHD、产妇和胎儿医学部(MFMU)网络。当前应用程序 描述我们的团队、环境和资源，以实现网络目标。自1992年以来，俄亥俄州 中心在进行临床和翻译方面表现出了强大的绩效和经验 研究建立在良好的基础设施和制度支持上。我们开发了一支强大的研究团队领导 由2019年应聘到俄亥俄州立大学韦克斯纳医疗中心的医学博士马吉德·科斯坦丁作为一个部门 母胎医学主任兼MFMU网络中心首席研究员，和Mark 兰登，医学博士，担任OG/GYN和候补PI部门的主席。除了工作效率， MFMU网络，包括PI和候补PI，在研究设计、招聘、数据方面带来了丰富的经验 分析和出版物。俄亥俄州立大学网络将在3点从不同人群中招募研究参与者 医疗中心每年出生的婴儿总数超过15,000人，其中许多是高危人群， 大多数人在这三个系统接受产前护理。我们的中心护士协调员安娜·巴塞洛缪， 公共卫生、RN、BSN、CCRP领导着一大批能够招聘和留住员工的教职员工和研究人员 在MFMU工作29年的经验增强了患者在优秀研究机构的背景 网络、参加NICHD绝产网络和北美胎儿的成员资格 治疗网络和俄亥俄围产期研究网络(OPRN)。我们受益于强大的生物信息学 结构和多功能的电子病历系统(EMR)，可捕获产前、产中和 产后数据在线，可供授权研究人员进行查询和自动 通知，一群非凡的产科超声医生，围产期流行病学家，和一个成熟的 研究基础设施由与全国儿童医院共享的CTSA赠款支持。我们的卫星 代顿的迈阿密山谷医院和辛辛那提的好心人医院都有出色的记录 最近一个网络周期的招聘情况，良好的研究文化，以及雄心勃勃的目标 MFMU网络参与。我们与Nationwide新生儿科的伙伴关系和强有力的合作 儿童医院在临床护理和研究、病理和临床实验室方面的优势 申请。我们期待着继续我们的服务、强劲的业绩和创新的传统 NICHD MFMU网络的下一个周期。我们接受RFA的捕获和参与性规定，并 随时准备以合作的方式完成正在进行的研究，从而实现网络的目标 所有的研究中心。

ABSTRACT This proposal describes the application of The Ohio State University (OSU) Center for continued participation in the Eunice Kennedy Shriver NICHD Maternal Fetal Medicine Units (MFMU) Network. The current application describes our team, environment and resources to meet the objectives of the Network. Since 1992, the OSU Center has demonstrated a strong performance and experience in conducting clinical and translational research based on excellent infrastructure and institutional support. We developed a strong research team led by Maged Costantine, MD who was recruited to the OSU Wexner Medical Center in 2019, as a Division Director for Maternal Fetal Medicine and Principal Investigator for the MFMU Network Center, and Mark Landon, MD who serves as Chair for the Department of OG/GYN and Alternate PI. In addition to productivity in the MFMU Network, both the PI and alternate PI, bring extensive experience in study design, recruitment, data analysis, and publications. The OSU Network will recruit study participants from diverse populations at 3 medical centers with a combined total of more than 15,000 annual births, many of them are high-risk, and the majority receiving prenatal care at the three systems. Our Center Nurse Coordinator, Anna Bartholomew, MPH, RN, BSN, CCRP, leads a large group of faculty & research staff capable of recruiting and retaining patients in the setting of an excellent research organization enhanced by 29 years of experience in the MFMU Network, participation in the NICHD Nulliparous Network, and memberships in the North American Fetal Treatment Network, and Ohio Perinatal Research Network (OPRN). We benefit from a robust bioinformatics structure and versatile Electronic Medical Record System (EMR) that captures antepartum, intrapartum, and postpartum data online and is readily available to authorized research personnel for query as well as automatic notification, an extraordinary group of obstetrical sonographers, perinatal epidemiologists, and a mature research infrastructure supported by a CTSA grant shared with Nationwide Children’s Hospital. Our satellite sites, Miami Valley Hospital in Dayton and Good Samaritan Hospital in Cincinnati, have an outstanding record of recruitment in the most recent Network cycle, well-established research culture, and ambitious goals for MFMU Network participation. Our partnership and strong collaboration with Neonatology at Nationwide Children’s Hospital in clinical care and research, Pathology and Clinical Laboratory add strengths to our application. We look forward to continuing our tradition of service, strong performance, and innovation in the next cycle of the NICHD MFMU Network. We accept the RFA’s capitation and participatory stipulations and stand ready to achieve the goals of the Network in completion of the ongoing studies in a collaborative way across all research centers.