NICHD Maternal Fetal Medicine Units Network

NICHD 母胎医学单位网络

基本信息

批准号：
9891074
负责人：
Maged Costantine
金额：
$ 26.62万
依托单位：
OHIO STATE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
1992
资助国家：
美国
起止时间：
1992-04-08 至 2021-03-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9891074
关键词：
Adherence American Bioinformatics Biological Birth Clinical Clinical Data Clinical Research Clinical Trials Clinical Trials Network Cytomegalovirus Data Analyses Data Collection Development Diagnosis Discipline of obstetrics Enrollment Environment Epidemiologist Epidemiology Extramural Activities Faculty Follow-Up Studies Funding Funding Opportunities Goals Grant Hepatitis C virus High Risk Woman Hospitals Infant Mortality Insulin Journals Leadership Low Birth Weight Infant Manuscripts Maternal-Fetal Medicine Units Network Medical Medical center Metformin National Institute of Child Health and Human Development Non-Insulin-Dependent Diabetes Mellitus Nulliparity Observational Study Ohio Participant Patient Recruitments Patients Pediatric Hospitals Performance Perinatal Perinatal mortality demographics Population Population Heterogeneity Positioning Attribute Prevention Principal Investigator Productivity Protocols documentation Publications Randomized Clinical Trials Reporting Research Research Infrastructure Research Personnel Research Project Grants Resources Services Site Staff Development Structure Symbiosis System Training and Education Translating Translational Research U-Series Cooperative Agreements Universities Work adverse pregnancy outcome base bench to bedside clinical care clinical center clinical infrastructure clinical investigation clinically relevant data quality design ethnic diversity experience faculty research fetal improved infant morbidity innovation member perinatal medicine premature protocol development public health relevance racial and ethnic racial diversity randomized trial recruit repository research and development response sample collection sociodemographics support network systems research

项目摘要

DESCRIPTION (provided by applicant): This proposal is the application of The Ohio State University (OSU) for continued participation in the NICHD Maternal Fetal Medicine Units (MFMU) Network. The current application describes our team, environment and resources to meet the objectives of the Network. Our newly energized team has a strong commitment to continue and expand our high level of performance in the Network since 1992. We have a strong experience in conducting clinical and translational research. Dr. Catalin Buhimschi was recruited to the OSU Wexner Medical Center in 2013. As Ohio State's Alternate Principal Investigator (PI) since 2014, he assumed local leadership, energized our research team, worked closely with Network's Publication Committee, and co-authored a concept presentation to the Steering Committee. The final cumulative performance report lists OSU as 1st in recruitment for HCV, 4th in ALPS, 6th in CMV trials, and 3rd - 4th best for overall recruitment. In the current application Dr. Buhimschi will serve as PI and work with Dr. Mark Landon, an established Network investigator, as Alternate PI. The OSU Network will recruit study participants from diverse populations at 3 medical centers with a combined total of more than 15,000 annual births. We have a large group of faculty & research staff capable of recruiting patients in the setting of an excellent research organization enhanced by 24 years of experience in the MFMU, participation in the NICHD Nulliparous Network, and memberships in the North American Fetal Treatment Network, and Ohio Perinatal Research Network (OPRN) - a large regional perinatal research repository with a state-of-the-art data collection system. We benefit from a robust bioinformatics structure, an extraordinary group of obstetrical sonographers, perinatal epidemiologists, and a mature research infrastructure supported by a CTSA grant shared with Nationwide Children's Hospital. Our satellite, Miami Valley Hospital in Dayton has an outstanding record of recruitment in the most recent Network cycle, 2011- 2016. Good Samaritan Hospital, the largest maternity service in Ohio, has worked closely with OSU faculty in statewide projects, has a well-established research culture and an ambitious agenda for MFMU Network participation. Our relationship with Nationwide Children's Hospital in clinical care and research has never been stronger, and includes a unique symbiosis with Center for Perinatal Research. We look forward to continuing our tradition of service and innovation in the next cycle of the NICHD MFMU Network. Our goal is to continue to be leaders in protocol development, recruitment, start-up and completion, data analysis, manuscript publication in top journals and support to the Network's tasks across all research protocols and centers.

描述（由应用程序提供）：该提案是俄亥俄州立大学（OSU）继续参与NICHD母体胎儿医学单位（MFMU）网络的应用。当前的应用程序描述了我们的团队，环境和资源以满足网络的目标。自1992年以来，我们新充满活力的团队致力于继续和扩大我们在网络中的高度绩效。我们在进行临床和翻译研究方面拥有丰富的经验。卡塔林·布希姆斯（Catalin Buhimschi）博士于2013年被招募到OSU Wexner医疗中心。作为俄亥俄州立大学的替代首席研究员（PI），他担任当地领导层，使我们的研究团队充满活力，并与Network的出版物委员会密切合作，并为指导委员会合作。最终的累积性能报告将OSU列为HCV招聘的第一名，阿尔卑斯山第四名，CMV试验中的第六名，总体招募第三名。在当前的应用程序中，Buhimschi博士将担任PI，并与已建立的网络调查员Mark Landon博士一起担任替代PI。 OSU网络将招募来自3个医疗中心的潜水员人群的研究参与者，总计超过15,000个年龄。 We have a large group of faculty & research staff Capable of recruiting patients in the setting of an excellent research organization enhanced by 24 years of experience in the MFMU, participation in the NICHD Nulliparous Network, and memberships in the North American Fetal Treatment Network, and Ohio Perinatal Research Network (OPRN) - a large regional perinatal research repository with a state-of-the-art data collection system.我们从强大的生物信息学结构中受益，这是一群非凡的妇产科医师，围产期流行病学家，以及由与全国儿童医院共享的CTSA赠款支持的成熟研究基础设施。我们位于代顿的卫星迈阿密山谷医院在2011年至2016年的最新网络周期中招募了杰出的记录。俄亥俄州最大的孕妇服务公司Good Samaritan医院在全州项目中与OSU教职员工密切合作，拥有良好的研究文化，并为MFMU网络参与而有一个雄心勃勃的Agernda。我们与全国儿童医院在临床护理和研究方面的关系从未如此牢固，其中包括一个独特的符号，并具有围产期研究中心。我们期待在NICHD MFMU网络的下一个周期中继续我们的服务和创新传统。我们的目标是继续成为协议开发，招聘，启动和完成的领导者，数据分析，顶级期刊中的手稿出版以及对所有研究协议和中心中网络任务的支持。