NICHD Maternal Fetal Medicine Units Network

NICHD 母胎医学单位网络

基本信息

  • 批准号:
    9891074
  • 负责人:
  • 金额:
    $ 26.62万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    1992
  • 资助国家:
    美国
  • 起止时间:
    1992-04-08 至 2021-03-31
  • 项目状态:
    已结题

项目摘要

 DESCRIPTION (provided by applicant): This proposal is the application of The Ohio State University (OSU) for continued participation in the NICHD Maternal Fetal Medicine Units (MFMU) Network. The current application describes our team, environment and resources to meet the objectives of the Network. Our newly energized team has a strong commitment to continue and expand our high level of performance in the Network since 1992. We have a strong experience in conducting clinical and translational research. Dr. Catalin Buhimschi was recruited to the OSU Wexner Medical Center in 2013. As Ohio State's Alternate Principal Investigator (PI) since 2014, he assumed local leadership, energized our research team, worked closely with Network's Publication Committee, and co-authored a concept presentation to the Steering Committee. The final cumulative performance report lists OSU as 1st in recruitment for HCV, 4th in ALPS, 6th in CMV trials, and 3rd - 4th best for overall recruitment. In the current application Dr. Buhimschi will serve as PI and work with Dr. Mark Landon, an established Network investigator, as Alternate PI. The OSU Network will recruit study participants from diverse populations at 3 medical centers with a combined total of more than 15,000 annual births. We have a large group of faculty & research staff capable of recruiting patients in the setting of an excellent research organization enhanced by 24 years of experience in the MFMU, participation in the NICHD Nulliparous Network, and memberships in the North American Fetal Treatment Network, and Ohio Perinatal Research Network (OPRN) - a large regional perinatal research repository with a state-of-the-art data collection system. We benefit from a robust bioinformatics structure, an extraordinary group of obstetrical sonographers, perinatal epidemiologists, and a mature research infrastructure supported by a CTSA grant shared with Nationwide Children's Hospital. Our satellite, Miami Valley Hospital in Dayton has an outstanding record of recruitment in the most recent Network cycle, 2011- 2016. Good Samaritan Hospital, the largest maternity service in Ohio, has worked closely with OSU faculty in statewide projects, has a well-established research culture and an ambitious agenda for MFMU Network participation. Our relationship with Nationwide Children's Hospital in clinical care and research has never been stronger, and includes a unique symbiosis with Center for Perinatal Research. We look forward to continuing our tradition of service and innovation in the next cycle of the NICHD MFMU Network. Our goal is to continue to be leaders in protocol development, recruitment, start-up and completion, data analysis, manuscript publication in top journals and support to the Network's tasks across all research protocols and centers.
 描述(由申请人提供):本提案是俄亥俄州立大学 (OSU) 继续参与 NICHD 母胎医学单位 (MFMU) 网络的申请。当前的申请描述了我们的团队、环境和资源,以实现网络的目标。自 1992 年以来,我们新近充满活力的团队坚定致力于继续并扩大我们在网络中的高水平绩效。我们在开展临床和转化研究方面拥有丰富的经验。 Catalin Buhimschi 博士于 2013 年被招募到 OSU Wexner 医疗中心。自 2014 年起,他担任俄亥俄州立大学的候补首席研究员 (PI),担任当地领导职务,为我们的研究团队注入活力,与 Network 的出版委员会密切合作,并共同撰写了向指导委员会提交的概念演示文稿。最终的累积绩效报告将 OSU 在 HCV 招募中排名第一,在 ALPS 中排名第四,在 CMV 试验中排名第六,在整体招募中排名第三至第四。在当前的申请中,Buhimschi 博士将担任 PI,并与知名网络调查员 Mark Landon 博士作为候补 PI 合作。 OSU 网络将在 3 个医疗中心招募来自不同人群的研究参与者,每年的出生人数总计超过 15,000 人。我们拥有一大批教职员工和研究人员,能够在优秀的研究组织中招募患者,该组织拥有 MFMU 24 年的经验、NICHD 未产儿网络的参与以及北美胎儿治疗网络和俄亥俄州围产期研究网络 (OPRN) 的成员资格,这是一个拥有最先进数据收集系统的大型区域围产期研究资源库。我们受益于强大的生物信息学结构、由产科超声医师、围产期流行病学家组成的杰出团队,以及由与全国儿童医院共享的 CTSA 拨款支持的成熟研究基础设施。我们的卫星,位于代顿的迈阿密谷医院在最近的网络周期(2011-2016 年)中拥有出色的招募记录。好撒玛利亚医院是俄亥俄州最大的产科服务机构,与 OSU 教师在全州项目中密切合作,拥有完善的研究文化和 MFMU 网络参与的雄心勃勃的议程。我们与全国儿童医院在临床护理和研究方面的关系从未如此紧密,并与围产期研究中心建立了独特的共生关系。我们期待在 NICHD MFMU 网络的下一个周期中继续我们的服务和创新传统。我们的目标是继续成为协议开发、招募、启动和完成、数据分析、在顶级期刊上发表手稿以及支持所有研究协议和中心的网络任务方面的领导者。

项目成果

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专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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Maged Costantine其他文献

Maged Costantine的其他文献

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{{ truncateString('Maged Costantine', 18)}}的其他基金

Developing Extracellular Vesicle Based MPRINT Translational Resource Platform for Monitoring Therapeutics Response During Pregnancy
开发基于细胞外囊泡的 MPRINT 转化资源平台,用于监测妊娠期间的治疗反应
  • 批准号:
    10747545
  • 财政年份:
    2023
  • 资助金额:
    $ 26.62万
  • 项目类别:
1/2 A randomized controlled trial of pravastatin to prevent preeclampsia in high-risk women
1/2 普伐他汀预防高危女性先兆子痫的随机对照试验
  • 批准号:
    10705607
  • 财政年份:
    2019
  • 资助金额:
    $ 26.62万
  • 项目类别:
1/2 A randomized controlled trial of pravastatin to prevent preeclampsia in high-risk women
1/2 普伐他汀预防高危女性先兆子痫的随机对照试验
  • 批准号:
    10087196
  • 财政年份:
    2019
  • 资助金额:
    $ 26.62万
  • 项目类别:
1/2 A randomized controlled trial of pravastatin to prevent preeclampsia in high-risk women
1/2 普伐他汀预防高危女性先兆子痫的随机对照试验
  • 批准号:
    10162643
  • 财政年份:
    2019
  • 资助金额:
    $ 26.62万
  • 项目类别:
1/2 A randomized controlled trial of pravastatin to prevent preeclampsia in high-risk women
1/2 普伐他汀预防高危女性先兆子痫的随机对照试验
  • 批准号:
    10455106
  • 财政年份:
    2019
  • 资助金额:
    $ 26.62万
  • 项目类别:
NICHD maternal fetal medicine units network
NICHD母胎医学单位网
  • 批准号:
    10681772
  • 财政年份:
    1992
  • 资助金额:
    $ 26.62万
  • 项目类别:
NICHD maternal fetal medicine units network
NICHD母胎医学单位网
  • 批准号:
    10379413
  • 财政年份:
    1992
  • 资助金额:
    $ 26.62万
  • 项目类别:
NICHD maternal fetal medicine units network
NICHD母胎医学单位网
  • 批准号:
    10254471
  • 财政年份:
    1992
  • 资助金额:
    $ 26.62万
  • 项目类别:
Comprehensive evaluation of the safety and utility of pravastatin in prevention of preeclampsia in high-risk pregnant women
普伐他汀预防高危孕妇子痫前期的安全性和有效性综合评价
  • 批准号:
    9119186
  • 财政年份:
  • 资助金额:
    $ 26.62万
  • 项目类别:

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