National Drug Early Warning System (NDEWS) Administrative Supplement - Poison Control

国家毒品早期预警系统 (NDEWS) 行政补充文件 - 毒物控制

• 批准号: 10382615
• 负责人: Linda B. Cottler
• 金额: $ 10.75万
• 依托单位: UNIVERSITY OF FLORIDA
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-05-01 至 2022-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10382615
• 关键词: Administrative Supplement; American; Back; COVID-19; Censuses; Cessation of life; Chemicals; Cocaine; Collection; Communities; Data; Data Collection; Data Set; Databases; Drug Administration Routes; Drug Exposure; Drug Monitoring; Drug usage; Early Diagnosis; Electronic Health Record; Ensure; Epidemiology; Exposure to; Feedback; Fentanyl; Future; Geography; Healthcare; Hour; Individual; Information Systems; Methamphetamine; Minor; Monitor; Morbidity - disease rate; National Institute of Drug Abuse; Parents; Patients; Pattern; Peer Review; Pharmaceutical Preparations; Plants; Poison; Poison Control Centers; Prevention; Process; Public Health; Publications; Reporting; Research; Scientist; Sentinel; Severities; Signal Transduction; Site; Source; Suicide attempt; Surveillance Methods; System; Time; Time trend; addiction; age group; analog; base; bath salts; epidemiology study; exposed human population; heroin use; mortality; novel; outreach; parent grant; poison control; prospective; response; sex; social media; statistics; substance use; surveillance data; synthetic cannabinoid; trend

SUMMARY OF PARENT GRANT AND PROPOSED SUPPLEMENT Parent Study: Through our parent U01, our National Drug Early Warning System (NDEWS) Coordinating Center aims to provide NIDA and the field with the most timely, salient, and valuable information on emerging substance use trends. By expanding data collection to include both former NDEWS sentinel sites as well as former Community Epidemiology Workgroup (CEWG) sites, and by incorporating novel surveillance methods to ensure early detection of signals of new psychoactive substances and known substances, our Early Warning Network extends geographic representation and provides a more complete picture of the size, direction, and depth of substance use patterns in all US Census regions. We use novel surveillance methods to ensure early detection of signals indicating emerging drug trends and harmonize surveillance data across sentinel and CEWG sites. We will also conduct on-the-ground epidemiologic investigations on topics of immediate crisis or need in order to provide functional feedback to impacted communities towards optimizing current and future response, and we will disseminate results rapidly to the scientific community and the public alike. Proposed Supplement: As an Early Warning System, NDEWS must be on the forefront of new trends in drug use, and drug-related morbidity and mortality. There is a lack of current or recent drug-related mortality data because processing of death information is lagged by months. Poison Control data, however, would allow us to detect emerging trends in both poisonings and deaths (‘exposures’) related to drug use in 48 states in almost real time. We will obtain Poison Control data from the Researched Abuse, Diversion and Addiction-Related Surveillance (RADARS) System and examine trends in exposures related to use of heroin, fentanyl and its analogs, cocaine, methamphetamine, and various new psychoactive substances, by month, for 12 months, to alert scientists and the public about trends in hotspots in near real time. Rates will be based on sex, Census age group, severity of effects (i.e., none, minor, moderate, major, death), route of drug administration, intent (e.g., intentional misuse, suicide attempt), and co-drug use. For Aim 1, we will acquire Poison Control data, monthly, and examine current trends in drug-related exposures and deaths, in near-real-time. For Aim 2, we will obtain data going as far back as 2015 and examine trends retrospectively. For Aim 3, we will rapidly disseminate statistics (monthly) on drug-related exposures to the scientific community and to the public through NDEWS listservs and media outreach and disseminate retrospective trends through peer-reviewed publications. We believe this is an extraordinary opportunity to quickly and frequently analyze drug exposure data and disseminate findings.

家长补助金和拟议补充摘要 家长研究：通过我们的家长 U01，我们的国家药物早期预警系统 (NDEWS) 协调 中心旨在为 NIDA 和该领域提供有关新兴市场的最及时、最突出、最有价值的信息。 物质使用趋势。通过扩大数据收集范围，将前 NDEWS 哨点站点以及 前社区流行病学工作组 (CEWG) 站点，并采用新颖的监测方法 为了确保及早发现新的精神活性物质和已知物质的信号，我们的早期预警 网络扩展了地理表征并提供了关于规模、方向和区域的更完整的图景。 美国所有人口普查地区物质使用模式的深度。我们使用新颖的监测方法来确保尽早 检测表明新出现的毒品趋势的信号并协调各个哨点和区域的监测数据 CEWG 网站。我们还将针对当前危机或紧急情况进行实地流行病学调查 需要向受影响的社区提供功能反馈，以优化当前和未来 回应，我们将迅速向科学界和公众传播结果。 拟议补充：作为早期预警系统，NDEWS 必须走在药物新趋势的最前沿 使用情况以及与毒品相关的发病率和死亡率。缺乏当前或近期与药物相关的死亡率数据 因为死亡信息的处理滞后了几个月。然而，毒物控制数据将使我们能够 检测近 48 个州与吸毒相关的中毒和死亡（“暴露”）的新趋势 即时的。我们将从滥用、转移和成瘾相关研究中获取毒物控制数据 监测（雷达）系统并检查与使用海洛因、芬太尼及其相关的暴露趋势 类似物、可卡因、甲基苯丙胺和各种新型精神活性物质，按月计算，持续 12 个月， 近乎实时地向科学家和公众发出有关热点趋势的警报。价格将根据性别、人口普查而定 年龄组、影响的严重程度（即无、轻微、中度、严重、死亡）、给药途径、意图 （例如，故意滥用、自杀未遂）和同时使用药物。对于目标 1，我们将获取毒物控制数据， 每月一次，并近乎实时地检查与毒品相关的接触和死亡的当前趋势。对于目标 2，我们 将获取追溯到 2015 年的数据并回顾性研究趋势。对于目标 3，我们将迅速 向科学界和公众传播有关毒品相关接触的统计数据（每月） 通过 NDEWS 列表服务和媒体宣传，并通过同行评审传播回顾趋势 出版物。我们相信这是快速、频繁地分析药物暴露的绝佳机会 数据并传播调查结果。