National Drug Early Warning System (NDEWS) Administrative Supplement - Poison Control

家长津贴及建议补助金摘要 家长研究：通过我们的家长U01，我们的国家药物预警系统(NDEWS)协调 中心旨在为NIDA和该领域提供有关新兴市场的最及时、最重要和最有价值的信息 物质使用趋势。通过扩大数据收集范围，包括前NDEWS哨所以及 前社区流行病学工作组(CEWG)地点，并纳入新的监测方法 为了确保及早发现新的精神活性物质和已知物质的信号，我们的早期预警 网络扩展了地理表示，并提供了更完整的大小、方向和 美国所有人口普查地区的物质使用深度模式。我们使用新的监控方法来确保及早 检测指示新出现的毒品趋势的信号，并协调哨兵和 CEWG站点。我们还将对迫在眉睫的危机或 需要为受影响的社区提供功能反馈，以优化当前和未来 我们将迅速向科学界和公众传播这一成果。 拟议补充：作为一个早期预警系统，NDEWS必须走在毒品新趋势的前列 以及与药物有关的发病率和死亡率。目前或最近缺乏与毒品有关的死亡率数据。 因为死亡信息的处理滞后了几个月。然而，毒物控制数据将使我们能够 在几乎48个州检测与药物使用有关的中毒和死亡(暴露)的新趋势 实时的。我们将从与滥用、转移注意力和上瘾相关的研究中获得毒物控制数据 监测(雷达)系统，并审查与使用海洛因、芬太尼及其相关药物有关的暴露趋势 类似物、可卡因、甲基苯丙胺和各种新的精神活性物质，按月，为期12个月，至 近乎实时地提醒科学家和公众热点地区的趋势。费率将基于性别、人口普查 年龄组，影响的严重程度(即无，轻微，中度，重大，死亡)，给药途径，意图 (例如，故意滥用、自杀未遂)和联合吸毒。对于目标1，我们将获得毒物控制数据， 每月，并近乎实时地审查与毒品有关的暴露和死亡的当前趋势。对于目标2，我们 将获得最早可追溯到2015年的数据，并回顾分析趋势。对于目标3，我们将迅速 向科学界和公众传播(每月)与毒品有关的暴露统计数据 通过NDEWS列表服务和媒体推广，并通过同行审查传播追溯趋势 出版物。我们相信，这是一个快速、频繁地分析药物暴露的绝佳机会。 数据和传播研究结果。

SUMMARY OF PARENT GRANT AND PROPOSED SUPPLEMENT Parent Study: Through our parent U01, our National Drug Early Warning System (NDEWS) Coordinating Center aims to provide NIDA and the field with the most timely, salient, and valuable information on emerging substance use trends. By expanding data collection to include both former NDEWS sentinel sites as well as former Community Epidemiology Workgroup (CEWG) sites, and by incorporating novel surveillance methods to ensure early detection of signals of new psychoactive substances and known substances, our Early Warning Network extends geographic representation and provides a more complete picture of the size, direction, and depth of substance use patterns in all US Census regions. We use novel surveillance methods to ensure early detection of signals indicating emerging drug trends and harmonize surveillance data across sentinel and CEWG sites. We will also conduct on-the-ground epidemiologic investigations on topics of immediate crisis or need in order to provide functional feedback to impacted communities towards optimizing current and future response, and we will disseminate results rapidly to the scientific community and the public alike. Proposed Supplement: As an Early Warning System, NDEWS must be on the forefront of new trends in drug use, and drug-related morbidity and mortality. There is a lack of current or recent drug-related mortality data because processing of death information is lagged by months. Poison Control data, however, would allow us to detect emerging trends in both poisonings and deaths (‘exposures’) related to drug use in 48 states in almost real time. We will obtain Poison Control data from the Researched Abuse, Diversion and Addiction-Related Surveillance (RADARS) System and examine trends in exposures related to use of heroin, fentanyl and its analogs, cocaine, methamphetamine, and various new psychoactive substances, by month, for 12 months, to alert scientists and the public about trends in hotspots in near real time. Rates will be based on sex, Census age group, severity of effects (i.e., none, minor, moderate, major, death), route of drug administration, intent (e.g., intentional misuse, suicide attempt), and co-drug use. For Aim 1, we will acquire Poison Control data, monthly, and examine current trends in drug-related exposures and deaths, in near-real-time. For Aim 2, we will obtain data going as far back as 2015 and examine trends retrospectively. For Aim 3, we will rapidly disseminate statistics (monthly) on drug-related exposures to the scientific community and to the public through NDEWS listservs and media outreach and disseminate retrospective trends through peer-reviewed publications. We believe this is an extraordinary opportunity to quickly and frequently analyze drug exposure data and disseminate findings.