Evaluation and validation of a novel instrument to assess the psychosocial and drug history backgrounds of pregnant women with or without Opioid Use Disorder

评估和验证一种新工具，用于评估患有或不患有阿片类药物使用障碍的孕妇的社会心理和药物史背景

• 批准号: 10382639
• 负责人: Heidi Preis
• 金额: $ 43.24万
• 依托单位: STATE UNIVERSITY NEW YORK STONY BROOK
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-30 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10382639
• 关键词: Affect; Allium schoenoprasum; Anxiety; Behavior; Biometry; Birth; COVID-19; COVID-19 pandemic; Clinical Psychology; Cohort Studies; Color; Common Data Element; Contracts; Data; Data Set; Discipline of obstetrics; Discrimination; Disease Outbreaks; Economics; Emergency Situation; Environmental Risk Factor; Epidemiology; Ethnic Origin; Evaluation; Event; Foundations; Funding; Future; Gender; Gender Identity; Geography; Gynecology; Health; Health Psychology; Health behavior; Healthcare; Individual; Infection; Interdisciplinary Study; Intervention; Investigation; Life; Long-Term Effects; Low Birth Weight Infant; Maternal Health; Measures; Mediating; Mental Depression; Mental Health; Morbidity - disease rate; Obsessive compulsive behavior; Outcome; Participant; Pathway interactions; Persons; Pharmaceutical Preparations; Postpartum Period; Pregnancy; Pregnant Women; Premature Birth; Prenatal care; Prevention; Psyche structure; Psychological Factors; Psychosocial Factor; Public Health; Race; Recording of previous events; Reporting; Request for Applications; Risk Factors; Role; Seeds; Social Psychology; Social Work; Social isolation; Socioeconomic Status; Stress; Structural Racism; Surveys; Symptoms; Time; Uncertainty; United States National Institutes of Health; Universities; Validation; World Health Organization; anxiety symptoms; behavioral health; child bearing; clinically significant; cohort; drug abuse in pregnancy; early experience; experience; generalized anxiety; hazard; health care availability; health care quality; health inequalities; instrument; maternal morbidity; maternal outcome; maternal risk; maternal stress; novel; opioid use disorder; pandemic disease; perceived stress; perinatal outcomes; physical conditioning; pregnant; prenatal; prospective; psychosocial; racial and ethnic; racism; recruit; sexual identity; social factors; social health determinants; socioeconomics

Abstract The COVID-19 pandemic provides an unprecedented opportunity to conduct prospective, longitudinal investigation of the effects of Social Determinants of Health (SDoH), including Structural Racism and Discrimination (SRD), and maternal stress on maternal physical and mental health morbidity. The Stony Brook COVID-19 Pregnancy Experiences (SB-COPE) Study, which forms the foundation for the proposed project, includes detailed prospective psychosocial data from over 7,400 persons who were pregnant at the beginning of the COVID-19 pandemic (n=4,400) or at the second U.S. COVID-19 surge (n=3,000), including 1,400 persons of color. The main objectives of this Urgent Competitive Revision proposal are to prospectively determine pandemic-related impacts on maternal stress, identify SDoH mechanisms associated with these impacts, and investigate the effects of stress on maternal morbidity and perinatal outcomes. The proposal seeks to extend assessment of the SB-COPE Study cohort for an additional year, and to follow participants into the first year postpartum, including, for some, into their next pregnancy. The proposed project will: Aim 1) Identify contributors to maternal stress during the pandemic. It is hypothesized that pregnant persons affected by SDoH, including SRD, will experience more stress as a result of the pandemic. SDoH to be investigated in the pandemic context include geographical disparities, race/ethnicity, relationship and economic status, and sexual and gender identity. SRD factors include prenatal gendered racism, everyday discrimination, and discrimination in healthcare. Stress factors include global perceived stress, pandemic- related stress, pregnancy-specific stress, and stressful life events. Aim 2) Identify contributors to prenatal and postpartum mental health morbidities during the pandemic. Persons with higher levels of stress are hypothesized to report greater mental health morbidities (depression, anxiety, and obsessive-compulsive symptoms) prenatally and in the postpartum period. Differential effects of stress types (e.g., pandemic-related stress, stressful life events) and interactions among stress, SDoH, and SRD (including healthcare access and quality) in predicting mental health outcomes will be examined. Aim 3) Identify pathways resulting in poorer maternal physical health and adverse perinatal outcomes during the pandemic. It is hypothesized that SDoH will predict greater likelihood of adverse perinatal outcomes (e.g., low birthweight, preterm birth; emergency delivery). This association is predicted to be mediated by prenatal maternal stress, maternal health behaviors, and healthcare access and quality. This critically timed project capitalizes on an existing, extensive baseline dataset (including NIH common data elements), large SB-COPE Study cohorts pregnant during critical pandemic periods, including a sizeable number of persons of color, and the highly relevant expertise of a multidisciplinary research team to rigorously identify SDoH, SRD, and explain their stress-related effects on pregnant persons in the context of the COVID-19 pandemic.

摘要 2019冠状病毒病大流行提供了一个前所未有的机会， 调查健康的社会决定因素（SDoH）的影响，包括结构性种族主义和 歧视（SRD）和产妇压力对产妇身心健康的影响。斯托尼布鲁克 COVID-19妊娠经历研究（SB-COPE）是拟议项目的基础， 包括来自7,400多名怀孕初期的人的详细的前瞻性心理社会数据。 COVID-19大流行（n= 4，400）或美国COVID-19第二次激增（n= 3，000），包括1，400 有色人种。本紧急竞争修订提案的主要目标是前瞻性地 确定流行病对孕产妇压力的影响，确定与这些影响相关的SDoH机制， 影响，并调查压力对孕产妇发病率和围产期结果的影响。该提案 寻求将SB-COPE研究队列的评估延长一年，并跟踪参与者 直到产后第一年，包括，对一些人来说，直到下一次怀孕。拟议项目将：目标1） 查明大流行期间造成产妇压力的因素。据推测，怀孕的人 受严重卫生问题影响的社区，包括社区关系科，将因疫情而承受更大的压力。SDoH将成为 在流行病背景下调查的因素包括地理差异、种族/民族、关系和经济 地位、性和性别认同。SRD因素包括产前性别种族主义，每天 歧视和医疗歧视。压力因素包括全球感知压力、流行病- 相关的压力，怀孕特有的压力，和压力的生活事件。目标2）确定产前诊断的贡献者 和产后精神健康发病率。压力较大的人是 假设报告更大的心理健康发病率（抑郁症，焦虑症和强迫症 症状）产前和产后期间。应力类型的不同影响（例如，疫情相关 压力、压力性生活事件）以及压力、SDoH和SRD（包括医疗保健获取和 质量）在预测心理健康结果方面的作用。目标3）确定导致更差 在大流行病期间，产妇的身体健康和不利的围产期结果。它是假设 SDoH将预测不良围产期结局的可能性更大（例如，低出生体重、早产; 紧急交付）。这种关联被预测为通过产前母体压力、母体健康 行为，以及医疗服务的获取和质量。这个关键的时间项目利用现有的，广泛的 基线数据集（包括NIH常见数据元素），SB-COPE研究期间妊娠的大型队列 关键的大流行时期，包括大量有色人种，以及高度相关的专业知识 一个多学科的研究小组，严格确定SDoH，SRD，并解释他们的压力相关的影响， 在COVID-19大流行的背景下，孕妇。

项目成果

Missingness patterns in a comprehensive instrument identifying psychosocial and substance use risk in antenatal care.

• DOI: 10.1080/02646838.2021.2004302
• 发表时间: 2023-09
• 期刊: JOURNAL OF REPRODUCTIVE AND INFANT PSYCHOLOGY
• 影响因子: 2.5
• 作者: Preis, Heidi;Djuric, Petar M.;Ajirak, Marzieh;Mane, Vibha;Garry, David J.;Garretto, Diana;Herrera, Kimberly;Heiselman, Cassandra;Marci, Lobel
• 通讯作者: Marci, Lobel

Common model of stress, anxiety, and depressive symptoms in pregnant women from seven high-income Western countries at the COVID-19 pandemic onset.

• DOI: 10.1016/j.socscimed.2022.115499
• 发表时间: 2022-12
• 期刊: SOCIAL SCIENCE & MEDICINE
• 影响因子: 5.4
• 作者: Lobel, Marci;Preis, Heidi;Mahaffey, Brittain;Schaal, Nora K.;Yirmiya, Karen;Atzil, Shir;Reuveni, Inbal;Balestrieri, Matteo;Penengo, Chiara;Colli, Chiara;Garzitto, Marco;Driul, Lorenza;Ilska, Michalina;Brandt-Salmeri, Anna;Kolodziej-Zaleskaj, Anna;Caparros-Gonzalez, Rafael A.;Castro, Rita Amiel;La Marca-Ghaemmaghami, Pearl;Meyerhoff, Hannah
• 通讯作者: Meyerhoff, Hannah

Saving time, signaling trust: Using the PROMOTE self-report screening instrument to enhance prenatal care quality and therapeutic relationships.

• DOI: 10.1016/j.pecinn.2022.100030
• 发表时间: 2022-12-01
• 期刊: PEC innovation
• 作者: Preis, Heidi;Whitney, Clare;Lobel, Marci
• 通讯作者: Lobel, Marci