Modified Use of E-cigarettes and Marketing on YouTube

项目摘要 我于2020年6月1日获得了我的第一个R 01（父母补助金）。然而，由于大学的招聘冻结， COVID-19大流行以及我孩子的出生和产假阻碍了项目的进展。因此， 行政补助金，侧重于支持经历过危急生活的首次受赠人 活动，将用于赶上从第一年的母赠款延迟的进展。请注意 该补助金的具体目标与原补助金的目标相同。的总体目标 家长补助金是为了了解年轻人修改电子烟的方式，他们这样做的动机， 和营销来源，使用YouTube分析，调查方法和专家评估。我们将 识别电子烟的改良用途，并使用虚构的青年YouTube观众资料进行营销， 电子烟使用浏览器插件和自定义脚本网络抓取，然后机器学习， 自动对视频进行编码，以识别电子烟的修改和营销来源。参谋的 烟草监管科学、社交媒体、青少年烟草使用、 毒理学、传播和烟草营销将运用他们的知识来评估 这些确定了电子烟在吸引力、成瘾和健康影响方面的修改用途，以确定那些 遵守FDA法规和通信。接下来我们将对这些进行深入分析 使用机器学习和详细的人类编码相结合的选择行为， YouTube视频了解：1）被修改的组件（例如，电池，墨盒/豆荚，电子液体），2） 修改的动机（例如，增强用户体验，减少感知伤害），3）营销来源 (e.g.,在线商店，支持电子烟的组织），以及4）吸引力（喜欢的数量，观看次数）。我们还将使用 对青少年和年轻成人电子烟使用者（N=1000）进行在线调查，以检查电子烟的流行率，吸引力， 与这些修改的用途及其预测因素相关的动机、风险感知和营销暴露（即， 人口统计学变量，上个月电子烟使用频率，电子烟依赖，其他 烟草/药物使用、人际和个人内部风险因素）。这项研究的结果将提供 FDA有新证据1）制定法规禁止制造和销售电子烟 可以由年轻人修改的组件，2）限制年轻人在社交媒体上进行电子烟营销 媒体，如YouTube，和3）发展预防运动，教育青少年的危害修改 电子烟

PROJECT SUMMARY I was awarded my first R01 (parent grant) on June 1, 2020. However, the university-wide hiring freeze due to the COVID-19 pandemic and the birth of my child and maternity leave set back the project progress. Thus, this Administrative Supplement, which is focused on supporting first-time grantees who experienced critical life events, will be used to catch up on the delayed progress from Year 1 of the parent grant. Please note that the Specific Aims of this Supplement remain the same as those of the parent grant. The overall goal of the parent grant is to understand ways in which youth modify e-cigarettes, their motivations for doing so, and marketing sources, using YouTube analysis, survey methodology, and expert evaluation. We will identify modified uses of e-cigarettes and marketing using fictitious youth YouTube viewer profiles to search for e-cigarettes using a browser plug-in and custom scripted web-crawling and then machine learning to automatically code the videos to identify e-cigarette modifications and marketing source. Our Advisory Committee (AC) of subject matter experts in tobacco regulatory science, social media, youth tobacco use, toxicology, communications, and tobacco marketing will apply their knowledge to assess the potential impact of these identified modified uses on appeal, addiction, and health effects of e-cigarettes to identify those which are amenable to FDA regulations and communications. We will then conduct an in-depth analysis of these selected behaviors using a combination of machine learning and detailed human coding on youth-accessible YouTube videos to understand: 1) components that are modified (e.g., batteries, cartridges/pods, e-liquids), 2) motivations for modification (e.g., enhance user experience, reduce perceived harm), 3) marketing sources (e.g., online shops, pro-e-cigarette organizations), and 4) appeal (number of likes, views). We will also use an online survey with adolescent and young adult e-cigarette users (N=1000) to examine the prevalence, appeal, motivations, risk perceptions, and marketing exposure related to these modified uses and their predictors (i.e., demographic variables, past-month e-cigarette use frequency, e-cigarette dependence, other tobacco/substance use, interpersonal and intrapersonal risk factors). The results of this study will provide the FDA with novel evidence to 1) develop regulations to prohibit the manufacturing and marketing of e-cigarette components that can be modified by youth, 2) restrict youth-accessible marketing of e-cigarettes on social media such as YouTube, and 3) develop prevention campaigns to educate youth about the harms of modifying e-cigarettes.