The Nurse Champion Model for Sickle Cell Disease Early Diagnosis and Care Access
镰状细胞病早期诊断和护理的护士冠军模型
基本信息
- 批准号:10383727
- 负责人:
- 金额:$ 17.66万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2021
- 资助国家:美国
- 起止时间:2021-04-15 至 2024-01-31
- 项目状态:已结题
- 来源:
- 关键词:AddressAdoptionAfrica South of the SaharaAfricanBirthBlood VesselsCaringCharacteristicsChildChild CareChild HealthChild MortalityChronic DiseaseClientClinicalClinical PathwaysCommunitiesComprehensive Health CareConsolidated Framework for Implementation ResearchCost AnalysisCounselingCountryDevelopmentDevicesDiagnosisDiagnosticDiscipline of NursingEarly DiagnosisEducationEducational StatusEffectivenessEndemic DiseasesEquipment and supply inventoriesEthnographyEvaluationEvidence based practiceFeasibility StudiesFocus GroupsFoundationsGeographic LocationsGoalsGroup InterviewsHIVHealthHealth PersonnelHealth Services AccessibilityHealth systemHemoglobinHumanHuman ResourcesInfantInterventionInterviewLaboratoriesLeadLifeLife ExpectancyMethodsModelingMorbidity - disease rateNeonatal ScreeningNewborn InfantNursesNursing ResearchOrganOutcomePatient EducationPerformancePhasePre-Post TestsPreventionPreventive carePreventive measurePrimary Health CareProcessProviderPublic HealthResearchResourcesRuralSickle Cell AnemiaSierra LeoneSiteStandardizationSurvival RateTimeTrainingTraining ProgramsUnited States National Institutes of Healthbaseburden of illnesscare coordinationcostdesigndisease diagnosisearly screeningeffectiveness implementation studyevidence basefield studyfollow-upformative assessmentimplementation barriersimplementation costimplementation facilitatorsimplementation frameworkimplementation outcomesimplementation studyimprovedinnovationinterestlaboratory experiencemortalityneonatenovelpeerperformance testspoint of care testingprimary care settingprogramsresearch studyresponsescreeningscreening programstandard of caresupport tools
项目摘要
Abstract
Sickle cell disease (SCD) is a major contributor to child morbidity and mortality. Life expectancy of babies with
SCD varies widely depending on geographic location. In the USA, universal newborn screening (NBS) facilitates
early diagnosis and prompt linkage to care with overall survival rate in SCD children greater than 94%. In Sub-
Saharan Africa (SSA) approximately 90% of the children born annually with SCD will die before their fifth birthday,
often undiagnosed. The absence of early diagnosis through laboratory-based NBS program is a major barrier to
implementation of timely preventive measures in SSA. Emergent, novel, inexpensive, point-of-care tests
(POCTs), with analytic characteristics and field-tested performance comparable to laboratory methods offer
intriguing options for early diagnosis of SCD in primary health centers (PHCs). Our study objective is to use a
type-2 hybrid implementation-effectiveness design to assess and pilot a SCD-POCT model in one urban and
one rural PHC over 6 months in Sierra Leone where our extant SCD health systems strengthening and human
capacity building research program is housed. Our rationale is that early SCD diagnosis in neonates
demonstrably decreases morbidity and mortality rates considerably in the first 5 years of life. In this feasibility
study, the research aims include developing and assisting PHCs in implementing the model; evaluating
processes/determinants of model implementation; and evaluating the model’s effectiveness, acceptability and
effects on provider and client outcomes. Using implementation science frameworks, our research team will
iteratively engage key stakeholders to inform the development of the PHC-based SCD-POCT model. The
evidence-informed nurse champion platform will frame the implementation model and will include pre/post-test
counseling, nurse administered POCT and care coordination. Nurses will complete a comprehensive provider
training program prior to implementing the model. Three specific aims undergird our study: (1) Assess barriers
and facilitators to primary health center provision of SCD-POCT with a nurse champion model; (2) Finalize an
implementation plan for the intervention using Implementation Mapping and stakeholder input; and (3) pilot the
nurse champion model in two primary health centers and evaluate determinants and implementation costs. The
process of developing and implementing the model will be described using implementation science frameworks,
ethnographic observations, qualitative interviews and implementation mapping to identify barriers/enablers.
Nurse and client outcomes will be assessed by focus groups and in-depth interviews. Model implementation will
be assessed qualitatively and quantitatively. Acceptability, barriers, and enablers will be examined qualitatively
based on focus group and interview responses. A preliminary costing assessment will consider the nurses and
research study financial outlays. We expect our study to establish the feasibility and scalability of SCD-POCT
intervention within extant and sustainable clinical pathways in PHCs in the sub-Saharan African settings.
摘要
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Cheedy Jaja其他文献
Cheedy Jaja的其他文献
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{{ truncateString('Cheedy Jaja', 18)}}的其他基金
Integrating Nurse Champion Model for Group Reproductive Genetic Counseling forSickle Cell Hemoglobinopathies into Primary Care: A Pilot Implementation ScienceStudy
将镰状细胞血红蛋白病团体生殖遗传咨询的护士冠军模型纳入初级保健:一项试点实施科学研究
- 批准号:
10491753 - 财政年份:2022
- 资助金额:
$ 17.66万 - 项目类别:
Integrating Nurse Champion Model for Group Reproductive Genetic Counseling forSickle Cell Hemoglobinopathies into Primary Care: A Pilot Implementation ScienceStudy
将镰状细胞血红蛋白病团体生殖遗传咨询的护士冠军模型纳入初级保健:一项试点实施科学研究
- 批准号:
10666605 - 财政年份:2022
- 资助金额:
$ 17.66万 - 项目类别:
Integrating Nurse Champion Model for Group Reproductive Genetic Counseling forSickle Cell Hemoglobinopathies into Primary Care: A Pilot Implementation ScienceStudy
将镰状细胞血红蛋白病团体生殖遗传咨询的护士冠军模型纳入初级保健:一项试点实施科学研究
- 批准号:
10553408 - 财政年份:2022
- 资助金额:
$ 17.66万 - 项目类别:
The Nurse Champion Model for Sickle Cell Disease Early Diagnosis and Care Access
镰状细胞病早期诊断和护理的护士冠军模型
- 批准号:
10640838 - 财政年份:2021
- 资助金额:
$ 17.66万 - 项目类别:
Integrating Nurse Champion Model for Group Reproductive Genetic Counseling for Sickle Cell Hemoglobinopathies into Primary Care: A Pilot Implementation Science Study
将镰状细胞血红蛋白病团体生殖遗传咨询的护士冠军模型纳入初级保健:一项试点实施科学研究
- 批准号:
10292492 - 财政年份:2021
- 资助金额:
$ 17.66万 - 项目类别:
The Nurse Champion Model for Sickle Cell Disease Early Diagnosis and Care Access
镰状细胞病早期诊断和护理的护士冠军模型
- 批准号:
10218332 - 财政年份:2021
- 资助金额:
$ 17.66万 - 项目类别:
Pharmacogenetic Optimization of Analgesic Prescribing in Sickle Cell Disease
镰状细胞病镇痛处方的药物遗传学优化
- 批准号:
8534286 - 财政年份:2011
- 资助金额:
$ 17.66万 - 项目类别:
Pharmacogenetic Optimization of Analgesic Prescribing in Sickle Cell Disease
镰状细胞病镇痛处方的药物遗传学优化
- 批准号:
8321947 - 财政年份:2011
- 资助金额:
$ 17.66万 - 项目类别:
Pharmacogenetic Optimization of Analgesic Prescribing in Sickle Cell Disease
镰状细胞病镇痛处方的药物遗传学优化
- 批准号:
8190974 - 财政年份:2011
- 资助金额:
$ 17.66万 - 项目类别:
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