A Novel Human Laboratory Model for Screening Medications for Alcohol Use Disorder

用于筛选酒精使用障碍药物的新型人体实验室模型

基本信息

  • 批准号:
    10387543
  • 负责人:
  • 金额:
    $ 4.68万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2021
  • 资助国家:
    美国
  • 起止时间:
    2021-08-10 至 2022-08-31
  • 项目状态:
    已结题

项目摘要

ABSTRACT This administrative supplement application is intended to support the timely and full completion of the proposed study and to offset delays caused by the COVID-19 Pandemic. As detailed in the application, we have dealt with a host of COVID-19 related delays, while also maintaining the laboratory open and conducting ongoing recruitment to the maximum degree allowed by the UCLA COVID-19 Response and Recovery Task Force. In this administrative supplement, we carefully justify the request for additional resources to effectively complete the original project and mitigate COVID-19 delays in recruitment. Despite the challenges of the COVID-19 pandemic our team has been resilient and hard-working. We have maintained recruitment efforts to the best of our ability and completed 19 randomizations during a full year of COVID-19 disruption. Further, we have kept the protocol integrity and have conducted daily telephone and zoom-based sessions, which enable close contact between participants and study staff. This allowed us to stay consistent with regard to the proposed protocol, provide careful medication management, verify medication compliance, and obtain all necessary clinical safety labs at the beginning of study participation. This administrative supplement will provide much-needed support a high-fidelity protocol that has been kept intact and operational despite substantial challenges associated with the pandemic.
摘要

项目成果

期刊论文数量(1)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
A novel human laboratory model for screening medications for alcohol use disorder.
  • DOI:
    10.1186/s13063-020-04842-w
  • 发表时间:
    2020-11-23
  • 期刊:
  • 影响因子:
    2.5
  • 作者:
    Ho D;Towns B;Grodin EN;Ray LA
  • 通讯作者:
    Ray LA
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LARA A. RAY其他文献

LARA A. RAY的其他文献

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{{ truncateString('LARA A. RAY', 18)}}的其他基金

The effects of stress on decision-making in alcohol use disorder: A translational approach
压力对酒精使用障碍决策的影响:转化方法
  • 批准号:
    10667891
  • 财政年份:
    2023
  • 资助金额:
    $ 4.68万
  • 项目类别:
Translational underpinnings of motivation for alcohol in humans
人类饮酒动机的转化基础
  • 批准号:
    10345709
  • 财政年份:
    2023
  • 资助金额:
    $ 4.68万
  • 项目类别:
Integrating findings across stages of medication development for AUD
整合 AUD 药物开发各个阶段的发现
  • 批准号:
    10353926
  • 财政年份:
    2021
  • 资助金额:
    $ 4.68万
  • 项目类别:
A Randomized Controlled Clinical Trial of the Neuroimmune Modulator Ibudilast for the Treatment of Alcohol Use Disorder
神经免疫调节剂异丁司特治疗酒精使用障碍的随机对照临床试验
  • 批准号:
    10387454
  • 财政年份:
    2021
  • 资助金额:
    $ 4.68万
  • 项目类别:
Integrating findings across stages of medication development for AUD
整合 AUD 药物开发各个阶段的发现
  • 批准号:
    10491120
  • 财政年份:
    2021
  • 资助金额:
    $ 4.68万
  • 项目类别:
A Novel Human Laboratory Model for Screening Medications for Alcohol Use Disorder
用于筛选酒精使用障碍药物的新型人体实验室模型
  • 批准号:
    10019310
  • 财政年份:
    2019
  • 资助金额:
    $ 4.68万
  • 项目类别:
A NOVEL HUMAN LABORATORY MODEL FOR SCREENING MEDICATIONS FOR ALCOHOL USE DISORDER
用于筛选酒精使用障碍药物的新型人体实验室模型
  • 批准号:
    10095672
  • 财政年份:
    2019
  • 资助金额:
    $ 4.68万
  • 项目类别:
A randomized controlled clinical trial of the neuroimmune modulator ibudilast for the treatment of alcohol use disorder
神经免疫调节剂异丁司特治疗酒精使用障碍的随机对照临床试验
  • 批准号:
    9883692
  • 财政年份:
    2018
  • 资助金额:
    $ 4.68万
  • 项目类别:
Clinical neuroscience of alcoholism: integrating neuroscience and clinical trials
酗酒的临床神经科学:神经科学与临床试验的结合
  • 批准号:
    10242146
  • 财政年份:
    2018
  • 资助金额:
    $ 4.68万
  • 项目类别:
Clinical neuroscience of alcoholism: integrating neuroscience and clinical trials
酗酒的临床神经科学:神经科学与临床试验的结合
  • 批准号:
    10481839
  • 财政年份:
    2018
  • 资助金额:
    $ 4.68万
  • 项目类别:

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