Novel Janus-type Antimicrobial Dressings for the Treatment of Biofilms in Chronic Wounds

用于治疗慢性伤口生物膜的新型 Janus 型抗菌敷料

• 批准号: 10389108
• 负责人: GUANGSHUN WANG
• 金额: $ 10.23万
• 依托单位: UNIVERSITY OF NEBRASKA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-10 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10389108
• 关键词: 3-Dimensional; Aftercare; Alanine; Amputation; Anti-Bacterial Agents; Antibiotic Resistance; Antibiotic Therapy; Antibiotics; Bacteria; Biopolymers; Cells; Cellular Infiltration; Cessation of life; Communities; Custom; Databases; Debridement; Diabetic Foot Ulcer; Diabetic mouse; Diffusion; ESKAPE pathogens; Electrospinning; Engineering; Failure; Gelatin; Genes; Geometry; Health; Health Care Costs; High Pressure Liquid Chromatography; Human; Immobilization; Immune response; In Vitro; Individual; Infection; Inflammation; Legal patent; Liquid substance; Membrane; Methods; Microbial Biofilms; Molds; Molecular; Monitor; Morphology; Operative Surgical Procedures; Patients; Peptide Hydrolases; Peptides; Performance; Porosity; Process; Protocols documentation; Pseudomonas aeruginosa; Quality of life; Refractory; Resistance; Scanning Electron Microscopy; Sepsis; Spectrum Analysis; Staphylococcus aureus; Sterile coverings; Streptococcus; Structure; Surface; Testing; Tissues; Treatment outcome; Type 2 diabetic; Wound Infection; antimicrobial; antimicrobial dressing; antimicrobial peptide; base; biomaterial compatibility; chronic infection; chronic wound; cost; cytokine; density; design; diabetic wound healing; effective intervention; effective therapy; efficacy testing; immunoregulation; improved; invention; mortality; nanofiber; novel; novel therapeutics; parent grant; pathogen; pathogenic bacteria; peptide analog; prevent; screening; skin wound; standard care; ultraviolet; wound; wound care; wound healing; wound treatment