Facility and Building System Upgrades Support for the Mason Biomedical Research Laboratory

为梅森生物医学研究实验室提供设施和建筑系统升级支持

• 批准号: 10394528
• 负责人: Farhang Alem
• 金额: $ 333万
• 依托单位: GEORGE MASON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-23 至 2025-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10394528
• 关键词: 2019-nCoV; Animals; Bacillus anthracis; Biomedical Research; Bioterrorism; Burkholderia pseudomallei; Communities; Eastern Equine Encephalitis Virus; Emerging Communicable Diseases; Equipment; Francisella tularensis; Funding; Goals; HIV; Human T-lymphotropic virus 1; Image; Infectious Diseases Research; Infrastructure; Laboratories; Laboratory Research; National Institute of Allergy and Infectious Disease; Positron-Emission Tomography; Recommendation; Research; Research Personnel; Resources; Rodent; System; United States; Universities; Venezuelan Equine Encephalitis Virus; Water; biodefense; biological research; fighting; nonhuman primate; operation; pandemic disease; pathogen; replacement tissue; response; success

Project Summary/Abstract In 2002, the NIAID convened a Panel on Bioterrorism and its implications for Biomedical Research to determine key priorities and short- and long-term goals for biodefense research in the United States. In response to the panel’s recommendations, the NIAID provided funding for the construction of two National Biocontainment Laboratories and 12 Regional Biocontainment Laboratories (RBLs). These installations have been an important resource for the nation as facilities where cutting edge scientific research on emerging infectious diseases and biodefense pathogens can be safely carried out. The Biological Research Laboratory (BRL) at George Mason University (GMU) is one of the 12 RBLs, and went into operation in July of 2010. In the decade since it opened its doors, GMU investigators have used the BRL to study select agents, such as Francisella tularensis, Burkholderia pseudomallei, Yesrinia pestis, Bacillus anthracis, Venezuelan equine encephalitis virus, Eastern equine encephalitis virus and SARS-CoV-2, as well as other pathogens, including, HIV and HTLV-1. To continue building on the success of the BRL, we are looking to upgrade aspects of the building’s infrastructure, in addition to purchasing new caging and state-of-the-art equipment that can serve the needs of the scientific community focused on infectious disease research and fighting the next pandemic. The Specific Aims of the proposal are as follows: 1) Purchase of animal caging to expand the BRL’s ability to house various species, from rodents to non-human primates; 2) Replacement of the tissue digester; 3) Purchase of imaging equipment, including the Fuji Vevo and Mediso PET-CT; 4) Installation of an automated watering system for the animal holding rooms; 5) Replacement of hot water heaters.

项目总结/文摘